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Found 12 Enz. Inhib. hit(s) with all data for entry = 50031550
TargetSerine/threonine-protein kinase mTOR(Rattus norvegicus)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315219(1-(4-(4,6-di(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)-...)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of rat brain mTOR assessed as p70S6K-GST protein phosphorylation after 30 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Rattus norvegicus)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315047(1-(4-(4,6-di(3-oxa-8-azabicyclo[3.2.1]octan-8-yl)-...)
Affinity DataIC50:  1nMAssay Description:Inhibition of rat brain mTOR assessed as p70S6K-GST protein phosphorylation after 30 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Rattus norvegicus)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315209(1-(4-(4,6-di(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)-...)
Affinity DataIC50:  1.70nMAssay Description:Inhibition of rat brain mTOR assessed as p70S6K-GST protein phosphorylation after 30 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Rattus norvegicus)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315212(1-(4-(4-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)-6-(3...)
Affinity DataIC50:  2nMAssay Description:Inhibition of rat brain mTOR assessed as p70S6K-GST protein phosphorylation after 30 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Rattus norvegicus)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315216(1-(4-(4,6-di(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)-...)
Affinity DataIC50:  2.5nMAssay Description:Inhibition of rat brain mTOR assessed as p70S6K-GST protein phosphorylation after 30 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Rattus norvegicus)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315218(1-cyclopropyl-3-(4-(4,6-di(8-oxa-3-azabicyclo[3.2....)
Affinity DataIC50:  2.60nMAssay Description:Inhibition of rat brain mTOR assessed as p70S6K-GST protein phosphorylation after 30 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Rattus norvegicus)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315217(1-(4-(4,6-di(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)-...)
Affinity DataIC50:  2.80nMAssay Description:Inhibition of rat brain mTOR assessed as p70S6K-GST protein phosphorylation after 30 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Rattus norvegicus)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315211(1-(4-(4,6-di((1S,4S)-2-oxa-5-azabicyclo[2.2.1]hept...)
Affinity DataIC50:  35nMAssay Description:Inhibition of rat brain mTOR assessed as p70S6K-GST protein phosphorylation after 30 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Rattus norvegicus)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315214(3,3'-(6-(2-(difluoromethyl)-1H-benzo[d]imidazol-1-...)
Affinity DataIC50:  44nMAssay Description:Inhibition of rat brain mTOR assessed as p70S6K-GST protein phosphorylation after 30 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Rattus norvegicus)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315213(2-(difluoromethyl)-1-(4,6-dimorpholin-4-yl-1,3,5-t...)
Affinity DataIC50:  45nMAssay Description:Inhibition of rat brain mTOR assessed as p70S6K-GST protein phosphorylation after 30 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Rattus norvegicus)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315215(3-(4-(2-(difluoromethyl)-1H-benzo[d]imidazol-1-yl)...)
Affinity DataIC50:  60nMAssay Description:Inhibition of rat brain mTOR assessed as p70S6K-GST protein phosphorylation after 30 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Rattus norvegicus)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315210(1-(4-(4,6-di((1R,4R)-2-oxa-5-azabicyclo[2.2.1]hept...)
Affinity DataIC50:  130nMAssay Description:Inhibition of rat brain mTOR assessed as p70S6K-GST protein phosphorylation after 30 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed