Compile Data Set for Download or QSAR
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Found 12 Enz. Inhib. hit(s) with all data for entry = 50031637
TargetDynamin-2(Homo sapiens (Human))
The University Of Newcastle

Curated by ChEMBL
LigandPNGBDBM50316543(CHEMBL1094197 | N,N'-(Propane-1,3-diyl)bis(6,7-dih...)
Affinity DataIC50:  290nMAssay Description:Inhibition of recombinant dynamin 2 expressed in Sf9 cells by malachite green GTPase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDynamin-2(Homo sapiens (Human))
The University Of Newcastle

Curated by ChEMBL
LigandPNGBDBM50316542(CHEMBL1098764 | N,N'-(Propane-1,3-diyl)bis(7,8-dih...)
Affinity DataIC50:  390nMAssay Description:Inhibition of recombinant dynamin 2 expressed in Sf9 cells by malachite green GTPase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDynamin-2(Homo sapiens (Human))
The University Of Newcastle

Curated by ChEMBL
LigandPNGBDBM50316539(CHEMBL1094850 | N,N'-(Ethane-1,2-diyl)bis(7,8-dihy...)
Affinity DataIC50:  440nMAssay Description:Inhibition of recombinant dynamin 2 expressed in Sf9 cells by malachite green GTPase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDynamin-2(Homo sapiens (Human))
The University Of Newcastle

Curated by ChEMBL
LigandPNGBDBM50316542(CHEMBL1098764 | N,N'-(Propane-1,3-diyl)bis(7,8-dih...)
Affinity DataIC50:  1.07E+4nMAssay Description:Inhibition of dynamin 2-mediated receptor-induced endocytosis in human U2OS cells assessed as uptake of Tf-TxR dye after 30 mins by automated acquisi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDynamin-2(Homo sapiens (Human))
The University Of Newcastle

Curated by ChEMBL
LigandPNGBDBM50316541(CHEMBL1096801 | N,N'-(Propane-1,3-diyl)bis(7-hydro...)
Affinity DataIC50:  1.67E+4nMAssay Description:Inhibition of recombinant dynamin 2 expressed in Sf9 cells by malachite green GTPase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDynamin-2(Homo sapiens (Human))
The University Of Newcastle

Curated by ChEMBL
LigandPNGBDBM50316540(CHEMBL1098763 | N,N'-(Propane-1,3-diyl)bis(8-hydro...)
Affinity DataIC50:  3.48E+4nMAssay Description:Inhibition of recombinant dynamin 2 expressed in Sf9 cells by malachite green GTPase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDynamin-1(Rattus norvegicus)
The University Of Newcastle

Curated by ChEMBL
LigandPNGBDBM50316543(CHEMBL1094197 | N,N'-(Propane-1,3-diyl)bis(6,7-dih...)
Affinity DataIC50:  4.04E+4nMAssay Description:Inhibition of dynamin 1-mediated synaptic vesicle endocytosis in Sprague-Dawley rat synaptosomes assessed as uptake of FM 4-64 dye after 30 mins by a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDynamin-2(Homo sapiens (Human))
The University Of Newcastle

Curated by ChEMBL
LigandPNGBDBM50316540(CHEMBL1098763 | N,N'-(Propane-1,3-diyl)bis(8-hydro...)
Affinity DataIC50:  4.82E+4nMAssay Description:Inhibition of dynamin 2-mediated receptor-induced endocytosis in human U2OS cells assessed as uptake of Tf-TxR dye after 30 mins by automated acquisi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDynamin-1(Rattus norvegicus)
The University Of Newcastle

Curated by ChEMBL
LigandPNGBDBM50316541(CHEMBL1096801 | N,N'-(Propane-1,3-diyl)bis(7-hydro...)
Affinity DataIC50:  6.61E+4nMAssay Description:Inhibition of dynamin 1-mediated synaptic vesicle endocytosis in Sprague-Dawley rat synaptosomes assessed as uptake of FM 4-64 dye after 30 mins by a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDynamin-2(Homo sapiens (Human))
The University Of Newcastle

Curated by ChEMBL
LigandPNGBDBM50316543(CHEMBL1094197 | N,N'-(Propane-1,3-diyl)bis(6,7-dih...)
Affinity DataIC50:  7.46E+4nMAssay Description:Inhibition of dynamin 2-mediated receptor-induced endocytosis in human U2OS cells assessed as uptake of Tf-TxR dye after 30 mins by automated acquisi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDynamin-1(Rattus norvegicus)
The University Of Newcastle

Curated by ChEMBL
LigandPNGBDBM50316542(CHEMBL1098764 | N,N'-(Propane-1,3-diyl)bis(7,8-dih...)
Affinity DataIC50:  9.95E+4nMAssay Description:Inhibition of dynamin 1-mediated synaptic vesicle endocytosis in Sprague-Dawley rat synaptosomes assessed as uptake of FM 4-64 dye after 30 mins by a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDynamin-2(Homo sapiens (Human))
The University Of Newcastle

Curated by ChEMBL
LigandPNGBDBM50316539(CHEMBL1094850 | N,N'-(Ethane-1,2-diyl)bis(7,8-dihy...)
Affinity DataIC50:  1.30E+6nMAssay Description:Inhibition of dynamin 2-mediated receptor-induced endocytosis in human U2OS cells assessed as uptake of Tf-TxR dye after 30 mins by automated acquisi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed