Compile Data Set for Download or QSAR
maximum 50k data
Found 15 Enz. Inhib. hit(s) with all data for entry = 50032245
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Homo sapiens (Human))
University Of Jordan

Curated by ChEMBL
LigandPNGBDBM5655(2-(2-chlorophenyl)-5,7-dihydroxy-8-[(3S,4R)-3-hydr...)
Affinity DataIC50:  30nMAssay Description:Inhibition of human GST-CDK1/cyclin B1 expressed in baculovirus using [gamma-33P]ATP after 45 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Homo sapiens (Human))
University Of Jordan

Curated by ChEMBL
LigandPNGBDBM7266(14-bromo-8,18-diazatetracyclo[9.7.0.0^{2,7}.0^{12,...)
Affinity DataIC50:  400nMAssay Description:Inhibition of human GST-CDK1/cyclin B1 expressed in baculovirus using [gamma-33P]ATP after 45 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
University Of Jordan

Curated by ChEMBL
LigandPNGBDBM7460(2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-4H-chrome...)
Affinity DataIC50:  450nMAssay Description:Inhibition of CDK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Homo sapiens (Human))
University Of Jordan

Curated by ChEMBL
LigandPNGBDBM50326169((S)-methyl 4-hydroxy-2-(4-hydroxy-3-(3-methylbut-2...)
Affinity DataIC50:  600nMAssay Description:Inhibition of human GST-CDK1/cyclin B1 expressed in baculovirus using [gamma-33P]ATP after 45 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
University Of Jordan

Curated by ChEMBL
LigandPNGBDBM50326170(2-((3-(7-chloroquinolin-4-ylamino)propyl)(ethyl)am...)
Affinity DataIC50:  830nMAssay Description:Inhibition of CDK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
University Of Jordan

Curated by ChEMBL
LigandPNGBDBM50326171(CHEMBL1243004 | dimethyl 6,6'-sulfonylbis(3-acetam...)
Affinity DataIC50:  910nMAssay Description:Inhibition of CDK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
University Of Jordan

Curated by ChEMBL
LigandPNGBDBM50326172(1-(2-hydroxyethyl)-3-(4-(trifluoromethyl)phenyl)th...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of CDK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
University Of Jordan

Curated by ChEMBL
LigandPNGBDBM50326173(1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)te...)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of CDK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
University Of Jordan

Curated by ChEMBL
LigandPNGBDBM50326174(2-hydroxyethyl 3,4-dichlorophenylcarbamodithioate ...)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of CDK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
University Of Jordan

Curated by ChEMBL
LigandPNGBDBM50326175(5-chloro-2-hydroxy-N-(3-hydroxypropyl)benzamide | ...)
Affinity DataIC50:  2.53E+3nMAssay Description:Inhibition of CDK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
University Of Jordan

Curated by ChEMBL
LigandPNGBDBM50326178(4-((1S,2S)-1-hydroxy-2-((S)-1-phenoxypropan-2-ylam...)
Affinity DataIC50:  2.90E+3nMAssay Description:Inhibition of CDK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
University Of Jordan

Curated by ChEMBL
LigandPNGBDBM50326176(2,2'-((5-chloro-8-hydroxyquinolin-7-yl)methylazane...)
Affinity DataIC50:  3.23E+3nMAssay Description:Inhibition of CDK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
University Of Jordan

Curated by ChEMBL
LigandPNGBDBM50326179(2-(N-(4,6-dimethoxypyrimidin-2-ylcarbamoyl)sulfamo...)
Affinity DataIC50:  3.60E+3nMAssay Description:Inhibition of CDK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
University Of Jordan

Curated by ChEMBL
LigandPNGBDBM50326177(5,5'-(hexane-1,6-diyl)bis(2-hydroxybenzaldehyde) |...)
Affinity DataIC50:  4.90E+3nMAssay Description:Inhibition of CDK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Homo sapiens (Human))
University Of Jordan

Curated by ChEMBL
LigandPNGBDBM5718(2,6,9-Trisubstituted purine deriv. 26 | 2-{[6-(ben...)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibition of human GST-CDK1/cyclin B1 expressed in baculovirus using [gamma-33P]ATP after 45 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank