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Found 78 Enz. Inhib. hit(s) with all data for entry = 50032553
TargetSodium channel protein type 10 subunit alpha(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50330935(CHEMBL1277958 | N-(m-Tolyl)-6-(4-ethoxyphenyl)-pyr...)
Affinity DataIC50:  1nMAssay Description:Inhibition of human recombinant NaV1.8 expressed in HEK293 cells by conventional voltageclamp electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 10 subunit alpha(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50330948(CHEMBL1277959 | N-(2-Methylbenzyl)-6-(4-ethoxyphen...)
Affinity DataIC50:  2nMAssay Description:Inhibition of human recombinant NaV1.8 expressed in HEK293 cells by conventional voltageclamp electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 10 subunit alpha(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50330949(CHEMBL1277877 | N-(3,5-Dimethylphenyl)-6-(4-ethoxy...)
Affinity DataIC50:  2nMAssay Description:Inhibition of human recombinant NaV1.8 expressed in HEK293 cells by conventional voltageclamp electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 10 subunit alpha(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50330933(CHEMBL1277514 | N-(3,5-Dimethylphenyl)-6-(4-chloro...)
Affinity DataIC50:  3nMAssay Description:Inhibition of human recombinant NaV1.8 expressed in HEK293 cells by conventional voltageclamp electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 10 subunit alpha(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50330945(CHEMBL1278223 | N-(m-Tolyl)-6-(4-trifluoromethoxyp...)
Affinity DataIC50:  5nMAssay Description:Inhibition of human recombinant NaV1.8 expressed in HEK293 cells by conventional voltageclamp electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 10 subunit alpha(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50330941(CHEMBL1277512 | N-(3,5-Dimethoxyphenyl)-6-(4-chlor...)
Affinity DataIC50:  6nMAssay Description:Inhibition of human recombinant NaV1.8 expressed in HEK293 cells by conventional voltageclamp electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 10 subunit alpha(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50330937(CHEMBL1277513 | N-(m-Tolyl)-6-(4-chlorophenyl)-pyr...)
Affinity DataIC50:  6nMAssay Description:Inhibition of human recombinant NaV1.8 expressed in HEK293 cells by conventional voltageclamp electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 10 subunit alpha(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50212239(5-(4-chlorophenyl)-N-(3,5-dimethoxyphenyl)furan-2-...)
Affinity DataIC50:  8nMAssay Description:Inhibition of human recombinant NaV1.8 expressed in HEK293 cells by conventional voltageclamp electrophysiology assayMore data for this Ligand-Target Pair
TargetSodium channel protein type 10 subunit alpha(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50330944(CHEMBL1278044 | N-(3,5-Dimethylphenyl)-6-(4-cyanop...)
Affinity DataIC50:  8nMAssay Description:Inhibition of human recombinant NaV1.8 expressed in HEK293 cells by conventional voltageclamp electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 10 subunit alpha(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50330949(CHEMBL1277877 | N-(3,5-Dimethylphenyl)-6-(4-ethoxy...)
Affinity DataIC50:  12nMAssay Description:Inhibition of tetrodotoxin-resistant NaV1.8 in rat dorsal root ganglion neurons at holding potential -100 mV by whole-cell patch clamp electrophysiol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 10 subunit alpha(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50330945(CHEMBL1278223 | N-(m-Tolyl)-6-(4-trifluoromethoxyp...)
Affinity DataIC50:  16nMAssay Description:Inhibition of tetrodotoxin-resistant NaV1.8 in rat dorsal root ganglion neurons at holding potential -100 mV by whole-cell patch clamp electrophysiol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 10 subunit alpha(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50330942(CHEMBL1278224 | N-(2-methylbenzyl)-6-(4-(trifluoro...)
Affinity DataIC50:  18nMAssay Description:Inhibition of human recombinant NaV1.8 expressed in HEK293 cells by conventional voltageclamp electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 10 subunit alpha(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50330932(CHEMBL1276882 | N-((2-Morpholin-4-yl-pyridin-3-yl)...)
Affinity DataIC50:  19nMAssay Description:Inhibition of human recombinant NaV1.8 expressed in HEK293 cells by conventional voltageclamp electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 10 subunit alpha(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50330948(CHEMBL1277959 | N-(2-Methylbenzyl)-6-(4-ethoxyphen...)
Affinity DataIC50:  19nMAssay Description:Inhibition of tetrodotoxin-resistant NaV1.8 in rat dorsal root ganglion neurons at holding potential -100 mV by whole-cell patch clamp electrophysiol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 10 subunit alpha(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50330938(CHEMBL1277607 | N-(4-Chlorophenethyl)-6-(4-chlorop...)
Affinity DataIC50:  19nMAssay Description:Inhibition of human recombinant NaV1.8 expressed in HEK293 cells by conventional voltageclamp electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 10 subunit alpha(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50329217(CHEMBL1271106 | N-(2-Methylbenzyl)-6-(4-trifluorom...)
Affinity DataIC50:  21nMAssay Description:Inhibition of human recombinant NaV1.8 expressed in HEK293 cells by conventional voltageclamp electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 10 subunit alpha(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50330943(CHEMBL1277606 | N-(2-Methylbenzyl)-6-(4-chlorophen...)
Affinity DataIC50:  27nMAssay Description:Inhibition of human recombinant NaV1.8 expressed in HEK293 cells by conventional voltageclamp electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 10 subunit alpha(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50330934(CHEMBL1277876 | N-((2-Pyrrolidin-1-yl-pyridin-3-yl...)
Affinity DataIC50:  30nMAssay Description:Inhibition of human recombinant NaV1.8 expressed in HEK293 cells by conventional voltageclamp electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 10 subunit alpha(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50329217(CHEMBL1271106 | N-(2-Methylbenzyl)-6-(4-trifluorom...)
Affinity DataIC50:  34nMAssay Description:Inhibition of tetrodotoxin-resistant NaV1.8 in rat dorsal root ganglion neurons at holding potential -100 mV by whole-cell patch clamp electrophysiol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 10 subunit alpha(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50330946(CHEMBL1277700 | N-((2-Morpholin-4-yl-pyridin-3-yl)...)
Affinity DataIC50:  37nMAssay Description:Inhibition of human recombinant NaV1.8 expressed in HEK293 cells by conventional voltageclamp electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 10 subunit alpha(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50330936(6-(4-cyanophenyl)-N-(3-isopropoxyphenyl)pyrazine-2...)
Affinity DataIC50:  49nMAssay Description:Inhibition of human recombinant NaV1.8 expressed in HEK293 cells by conventional voltageclamp electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 10 subunit alpha(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50330933(CHEMBL1277514 | N-(3,5-Dimethylphenyl)-6-(4-chloro...)
Affinity DataIC50:  52nMAssay Description:Inhibition of tetrodotoxin-resistant NaV1.8 in rat dorsal root ganglion neurons at holding potential -100 mV by whole-cell patch clamp electrophysiol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 10 subunit alpha(Mus musculus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50330949(CHEMBL1277877 | N-(3,5-Dimethylphenyl)-6-(4-ethoxy...)
Affinity DataIC50:  56nMAssay Description:Inhibition of mouse NaV1.8 expressed in HEK293 cells by isotopic efflux assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 10 subunit alpha(Mus musculus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50329217(CHEMBL1271106 | N-(2-Methylbenzyl)-6-(4-trifluorom...)
Affinity DataIC50:  58nMAssay Description:Inhibition of mouse NaV1.8 expressed in HEK293 cells by isotopic efflux assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 10 subunit alpha(Mus musculus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50330945(CHEMBL1278223 | N-(m-Tolyl)-6-(4-trifluoromethoxyp...)
Affinity DataIC50:  66nMAssay Description:Inhibition of mouse NaV1.8 expressed in HEK293 cells by isotopic efflux assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 10 subunit alpha(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50330935(CHEMBL1277958 | N-(m-Tolyl)-6-(4-ethoxyphenyl)-pyr...)
Affinity DataIC50:  68nMAssay Description:Inhibition of tetrodotoxin-resistant NaV1.8 in rat dorsal root ganglion neurons at holding potential -100 mV by whole-cell patch clamp electrophysiol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 10 subunit alpha(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50330944(CHEMBL1278044 | N-(3,5-Dimethylphenyl)-6-(4-cyanop...)
Affinity DataIC50:  84nMAssay Description:Inhibition of tetrodotoxin-resistant NaV1.8 in rat dorsal root ganglion neurons at holding potential -100 mV by whole-cell patch clamp electrophysiol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 10 subunit alpha(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50330932(CHEMBL1276882 | N-((2-Morpholin-4-yl-pyridin-3-yl)...)
Affinity DataIC50:  85nMAssay Description:Inhibition of tetrodotoxin-resistant NaV1.8 in rat dorsal root ganglion neurons at holding potential -100 mV by whole-cell patch clamp electrophysiol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 10 subunit alpha(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50330940(CHEMBL1276881 | N-((2-Chloropyridin-3-yl)methyl)-6...)
Affinity DataIC50:  90nMAssay Description:Inhibition of tetrodotoxin-resistant NaV1.8 in rat dorsal root ganglion neurons at holding potential -100 mV by whole-cell patch clamp electrophysiol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 10 subunit alpha(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50330940(CHEMBL1276881 | N-((2-Chloropyridin-3-yl)methyl)-6...)
Affinity DataIC50:  99nMAssay Description:Inhibition of human recombinant NaV1.8 expressed in HEK293 cells by conventional voltageclamp electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 10 subunit alpha(Mus musculus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50330948(CHEMBL1277959 | N-(2-Methylbenzyl)-6-(4-ethoxyphen...)
Affinity DataIC50:  110nMAssay Description:Inhibition of mouse NaV1.8 expressed in HEK293 cells by isotopic efflux assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 10 subunit alpha(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50330943(CHEMBL1277606 | N-(2-Methylbenzyl)-6-(4-chlorophen...)
Affinity DataIC50:  110nMAssay Description:Inhibition of tetrodotoxin-resistant NaV1.8 in rat dorsal root ganglion neurons at holding potential -100 mV by whole-cell patch clamp electrophysiol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 10 subunit alpha(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50330936(6-(4-cyanophenyl)-N-(3-isopropoxyphenyl)pyrazine-2...)
Affinity DataIC50:  130nMAssay Description:Inhibition of tetrodotoxin-resistant NaV1.8 in rat dorsal root ganglion neurons at holding potential -100 mV by whole-cell patch clamp electrophysiol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 10 subunit alpha(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50212239(5-(4-chlorophenyl)-N-(3,5-dimethoxyphenyl)furan-2-...)
Affinity DataIC50:  140nMAssay Description:Inhibition of tetrodotoxin-resistant NaV1.8 in rat dorsal root ganglion neurons at holding potential -100 mV by whole-cell patch clamp electrophysiol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 10 subunit alpha(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50330939(CHEMBL1278138 | N-(2-Methylbenzyl)-6-(4-cyanopheny...)
Affinity DataIC50:  150nMAssay Description:Inhibition of human recombinant NaV1.8 expressed in HEK293 cells by conventional voltageclamp electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 10 subunit alpha(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50330942(CHEMBL1278224 | N-(2-methylbenzyl)-6-(4-(trifluoro...)
Affinity DataIC50:  170nMAssay Description:Inhibition of tetrodotoxin-resistant NaV1.8 in rat dorsal root ganglion neurons at holding potential -100 mV by whole-cell patch clamp electrophysiol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 10 subunit alpha(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50330941(CHEMBL1277512 | N-(3,5-Dimethoxyphenyl)-6-(4-chlor...)
Affinity DataIC50:  190nMAssay Description:Inhibition of tetrodotoxin-resistant NaV1.8 in rat dorsal root ganglion neurons at holding potential -100 mV by whole-cell patch clamp electrophysiol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 10 subunit alpha(Mus musculus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50330934(CHEMBL1277876 | N-((2-Pyrrolidin-1-yl-pyridin-3-yl...)
Affinity DataIC50:  210nMAssay Description:Inhibition of mouse NaV1.8 expressed in HEK293 cells by isotopic efflux assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 10 subunit alpha(Mus musculus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50330942(CHEMBL1278224 | N-(2-methylbenzyl)-6-(4-(trifluoro...)
Affinity DataIC50:  240nMAssay Description:Inhibition of mouse NaV1.8 expressed in HEK293 cells by isotopic efflux assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 10 subunit alpha(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50330937(CHEMBL1277513 | N-(m-Tolyl)-6-(4-chlorophenyl)-pyr...)
Affinity DataIC50:  280nMAssay Description:Inhibition of tetrodotoxin-resistant NaV1.8 in rat dorsal root ganglion neurons at holding potential -100 mV by whole-cell patch clamp electrophysiol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 10 subunit alpha(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50330946(CHEMBL1277700 | N-((2-Morpholin-4-yl-pyridin-3-yl)...)
Affinity DataIC50:  280nMAssay Description:Inhibition of tetrodotoxin-resistant NaV1.8 in rat dorsal root ganglion neurons at holding potential -100 mV by whole-cell patch clamp electrophysiol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 10 subunit alpha(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50330947(CHEMBL1277792 | N-((3-Morpholinopyridin-4-yl)methy...)
Affinity DataIC50:  320nMAssay Description:Inhibition of human recombinant NaV1.8 expressed in HEK293 cells by conventional voltageclamp electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 2 subunit alpha(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50330949(CHEMBL1277877 | N-(3,5-Dimethylphenyl)-6-(4-ethoxy...)
Affinity DataIC50:  360nMAssay Description:Inhibition of human recombinant NaV1.2 by electrophysiologyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 10 subunit alpha(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50330938(CHEMBL1277607 | N-(4-Chlorophenethyl)-6-(4-chlorop...)
Affinity DataIC50:  360nMAssay Description:Inhibition of tetrodotoxin-resistant NaV1.8 in rat dorsal root ganglion neurons at holding potential -100 mV by whole-cell patch clamp electrophysiol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 10 subunit alpha(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50330939(CHEMBL1278138 | N-(2-Methylbenzyl)-6-(4-cyanopheny...)
Affinity DataIC50:  450nMAssay Description:Inhibition of tetrodotoxin-resistant NaV1.8 in rat dorsal root ganglion neurons at holding potential -100 mV by whole-cell patch clamp electrophysiol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 10 subunit alpha(Mus musculus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50330944(CHEMBL1278044 | N-(3,5-Dimethylphenyl)-6-(4-cyanop...)
Affinity DataIC50:  470nMAssay Description:Inhibition of mouse NaV1.8 expressed in HEK293 cells by isotopic efflux assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 2 subunit alpha(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50330948(CHEMBL1277959 | N-(2-Methylbenzyl)-6-(4-ethoxyphen...)
Affinity DataIC50:  470nMAssay Description:Inhibition of human recombinant NaV1.2 by electrophysiologyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 10 subunit alpha(Mus musculus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50330932(CHEMBL1276882 | N-((2-Morpholin-4-yl-pyridin-3-yl)...)
Affinity DataIC50:  480nMAssay Description:Inhibition of mouse NaV1.8 expressed in HEK293 cells by isotopic efflux assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 10 subunit alpha(Mus musculus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50330933(CHEMBL1277514 | N-(3,5-Dimethylphenyl)-6-(4-chloro...)
Affinity DataIC50:  490nMAssay Description:Inhibition of mouse NaV1.8 expressed in HEK293 cells by isotopic efflux assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 10 subunit alpha(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50330934(CHEMBL1277876 | N-((2-Pyrrolidin-1-yl-pyridin-3-yl...)
Affinity DataIC50:  550nMAssay Description:Inhibition of tetrodotoxin-resistant NaV1.8 in rat dorsal root ganglion neurons at holding potential -100 mV by whole-cell patch clamp electrophysiol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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