Compile Data Set for Download or QSAR
maximum 50k data
Found 70 Enz. Inhib. hit(s) with all data for entry = 50032672
LigandPNGBDBM50333027(3-(Pyridin-4-ylethynyl)-1H-indazole | CHEMBL163189...)
Affinity DataIC50:  360nMAssay Description:Inhibition of PI3Kalpha by LanthaScreen Eu kinase binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50333031(4-((1H-Indazol-3-yl)ethynyl)aniline | CHEMBL163188...)
Affinity DataIC50:  1.05E+3nMAssay Description:Inhibition of PI3Kalpha by LanthaScreen Eu kinase binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50333028(3-(Pyridin-3-ylethynyl)-1H-indazole | CHEMBL163189...)
Affinity DataIC50:  1.85E+3nMAssay Description:Inhibition of PI3Kalpha by LanthaScreen Eu kinase binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50333017(3-(Pyridin-4-ylethynyl)-1H-pyrazolo[3,4-b]pyridine...)
Affinity DataIC50:  3.05E+3nMAssay Description:Inhibition of PI3Kalpha by LanthaScreen Eu kinase binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50333027(3-(Pyridin-4-ylethynyl)-1H-indazole | CHEMBL163189...)
Affinity DataIC50:  3.87E+3nMAssay Description:Inhibition of PDK1 by Z'-LYTE kinase activity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50333031(4-((1H-Indazol-3-yl)ethynyl)aniline | CHEMBL163188...)
Affinity DataIC50:  4.97E+3nMAssay Description:Inhibition of mTOR by LanthaScreen Eu kinase binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50333016(3-(Pyridin-2-ylethynyl)-1H-pyrazolo[3,4-b]pyridine...)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of mTOR by LanthaScreen Eu kinase binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50333024(3-((1H-Indazol-3-yl)ethynyl)aniline | CHEMBL163189...)
Affinity DataIC50:  5.10E+3nMAssay Description:Inhibition of mTORC1 expressed in HEK293 cells assessed as PRAS40 Ser183 phosphorylation level by LanthaScreen cellular assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50333024(3-((1H-Indazol-3-yl)ethynyl)aniline | CHEMBL163189...)
Affinity DataIC50:  5.12E+3nMAssay Description:Inhibition of PI3Kalpha by LanthaScreen Eu kinase binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50333016(3-(Pyridin-2-ylethynyl)-1H-pyrazolo[3,4-b]pyridine...)
Affinity DataIC50:  9.00E+3nMAssay Description:Inhibition of PI3Kalpha by LanthaScreen Eu kinase binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50333016(3-(Pyridin-2-ylethynyl)-1H-pyrazolo[3,4-b]pyridine...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of mTORC1 expressed in HEK293 cells assessed as PRAS40 Ser183 phosphorylation level by LanthaScreen cellular assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50333017(3-(Pyridin-4-ylethynyl)-1H-pyrazolo[3,4-b]pyridine...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of mTOR by LanthaScreen Eu kinase binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50333027(3-(Pyridin-4-ylethynyl)-1H-indazole | CHEMBL163189...)
Affinity DataIC50:  1.07E+4nMAssay Description:Inhibition of mTOR by LanthaScreen Eu kinase binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50333031(4-((1H-Indazol-3-yl)ethynyl)aniline | CHEMBL163188...)
Affinity DataIC50:  1.08E+4nMAssay Description:Inhibition of mTORC1 expressed in HEK293 cells assessed as PRAS40 Ser183 phosphorylation level by LanthaScreen cellular assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50333024(3-((1H-Indazol-3-yl)ethynyl)aniline | CHEMBL163189...)
Affinity DataIC50:  1.26E+4nMAssay Description:Inhibition of PDK1 by Z'-LYTE kinase activity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50333027(3-(Pyridin-4-ylethynyl)-1H-indazole | CHEMBL163189...)
Affinity DataIC50:  1.36E+4nMAssay Description:Inhibition of mTORC1 expressed in HEK293 cells assessed as PRAS40 Ser183 phosphorylation level by LanthaScreen cellular assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50333017(3-(Pyridin-4-ylethynyl)-1H-pyrazolo[3,4-b]pyridine...)
Affinity DataIC50:  1.91E+4nMAssay Description:Inhibition of mTORC1 expressed in HEK293 cells assessed as PRAS40 Ser183 phosphorylation level by LanthaScreen cellular assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50333028(3-(Pyridin-3-ylethynyl)-1H-indazole | CHEMBL163189...)
Affinity DataIC50:  2.08E+4nMAssay Description:Inhibition of PDK1 by Z'-LYTE kinase activity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50333025(3-(Pyridin-2-ylethynyl)-1H-indazole | CHEMBL163189...)
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of PDK1 by Z'-LYTE kinase activity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50333027(3-(Pyridin-4-ylethynyl)-1H-indazole | CHEMBL163189...)
Affinity DataIC50:  3.90E+4nMAssay Description:Inhibition of PI3KdeltaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50333031(4-((1H-Indazol-3-yl)ethynyl)aniline | CHEMBL163188...)
Affinity DataIC50:  3.92E+4nMAssay Description:Inhibition of PDK1 by Z'-LYTE kinase activity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50333027(3-(Pyridin-4-ylethynyl)-1H-indazole | CHEMBL163189...)
Affinity DataIC50:  4.00E+4nMAssay Description:Inhibition of PI3KgammaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50333016(3-(Pyridin-2-ylethynyl)-1H-pyrazolo[3,4-b]pyridine...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of PDK1 by Z'-LYTE kinase activity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50333030(3-(Phenylethynyl)-1H-indazole | CHEMBL1631889)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of mTORC1 expressed in HEK293 cells assessed as PRAS40 Ser183 phosphorylation level by LanthaScreen cellular assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50333028(3-(Pyridin-3-ylethynyl)-1H-indazole | CHEMBL163189...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of mTORC1 expressed in HEK293 cells assessed as PRAS40 Ser183 phosphorylation level by LanthaScreen cellular assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50333026(3-(1H-Indazol-3-yl)-N,N-dimethylprop-2-yn-1-amine ...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of mTORC1 expressed in HEK293 cells assessed as PRAS40 Ser183 phosphorylation level by LanthaScreen cellular assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50333025(3-(Pyridin-2-ylethynyl)-1H-indazole | CHEMBL163189...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of mTORC1 expressed in HEK293 cells assessed as PRAS40 Ser183 phosphorylation level by LanthaScreen cellular assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50333026(3-(1H-Indazol-3-yl)-N,N-dimethylprop-2-yn-1-amine ...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of PI3Kalpha by LanthaScreen Eu kinase binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50333022(3-(Cyclopropylethynyl)-1H-indazole | CHEMBL1631897)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of mTORC1 expressed in HEK293 cells assessed as PRAS40 Ser183 phosphorylation level by LanthaScreen cellular assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50333021(2-((1H-Indazol-3-yl)ethynyl)aniline | CHEMBL163189...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of mTORC1 expressed in HEK293 cells assessed as PRAS40 Ser183 phosphorylation level by LanthaScreen cellular assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50333018(4-((1H-Indazol-3-yl)ethynyl)benzonitrile | CHEMBL1...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of mTORC1 expressed in HEK293 cells assessed as PRAS40 Ser183 phosphorylation level by LanthaScreen cellular assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50333030(3-(Phenylethynyl)-1H-indazole | CHEMBL1631889)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of PDK1 by Z'-LYTE kinase activity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50333017(3-(Pyridin-4-ylethynyl)-1H-pyrazolo[3,4-b]pyridine...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of PDK1 by Z'-LYTE kinase activity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50333023(3-(Cyclopentylethynyl)-1H-indazole | CHEMBL1631896)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of mTORC1 expressed in HEK293 cells assessed as PRAS40 Ser183 phosphorylation level by LanthaScreen cellular assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50333019(3-(Thiophen-3-ylethynyl)-1H-indazole | CHEMBL16319...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of mTORC1 expressed in HEK293 cells assessed as PRAS40 Ser183 phosphorylation level by LanthaScreen cellular assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50333020(3-((3,5-Bis(trifluoromethyl)phenyl)ethynyl)-1Hinda...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of mTORC1 expressed in HEK293 cells assessed as PRAS40 Ser183 phosphorylation level by LanthaScreen cellular assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50333018(4-((1H-Indazol-3-yl)ethynyl)benzonitrile | CHEMBL1...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of PDK1 by Z'-LYTE kinase activity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50333019(3-(Thiophen-3-ylethynyl)-1H-indazole | CHEMBL16319...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of PDK1 by Z'-LYTE kinase activity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50333020(3-((3,5-Bis(trifluoromethyl)phenyl)ethynyl)-1Hinda...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of PDK1 by Z'-LYTE kinase activity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50333021(2-((1H-Indazol-3-yl)ethynyl)aniline | CHEMBL163189...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of PDK1 by Z'-LYTE kinase activity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50333022(3-(Cyclopropylethynyl)-1H-indazole | CHEMBL1631897)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of PDK1 by Z'-LYTE kinase activity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50333023(3-(Cyclopentylethynyl)-1H-indazole | CHEMBL1631896)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of PDK1 by Z'-LYTE kinase activity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50333026(3-(1H-Indazol-3-yl)-N,N-dimethylprop-2-yn-1-amine ...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of PDK1 by Z'-LYTE kinase activity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50333029(3-((3,5-Difluorophenyl)ethynyl)-1H-indazole | CHEM...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of PDK1 by Z'-LYTE kinase activity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50333018(4-((1H-Indazol-3-yl)ethynyl)benzonitrile | CHEMBL1...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of mTOR by LanthaScreen Eu kinase binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50333019(3-(Thiophen-3-ylethynyl)-1H-indazole | CHEMBL16319...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of mTOR by LanthaScreen Eu kinase binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50333020(3-((3,5-Bis(trifluoromethyl)phenyl)ethynyl)-1Hinda...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of mTOR by LanthaScreen Eu kinase binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50333021(2-((1H-Indazol-3-yl)ethynyl)aniline | CHEMBL163189...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of mTOR by LanthaScreen Eu kinase binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50333022(3-(Cyclopropylethynyl)-1H-indazole | CHEMBL1631897)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of mTOR by LanthaScreen Eu kinase binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50333023(3-(Cyclopentylethynyl)-1H-indazole | CHEMBL1631896)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of mTOR by LanthaScreen Eu kinase binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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