Compile Data Set for Download or QSAR
maximum 50k data
Found 5 Enz. Inhib. hit(s) with all data for entry = 50045926
TargetCytochrome P450 3A4(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50336575(CHEMBL1672054 | cis-(1'-Acetyl-N-{(1R)-1-[3,5-bis(...)
Affinity DataKi:  4.93E+3nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam substrate by HPLC-MS/MS methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50088501(CHEMBL3526984)
Affinity DataIC50:  5.60E+3nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using nifedipine substrate by HPLC-MS/MS methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50088501(CHEMBL3526984)
Affinity DataIC50:  8.22E+3nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam substrate by HPLC-MS/MS methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50336575(CHEMBL1672054 | cis-(1'-Acetyl-N-{(1R)-1-[3,5-bis(...)
Affinity DataIC50:  9.72E+3nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using nifedipine substrate by HPLC-MS/MS methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50336575(CHEMBL1672054 | cis-(1'-Acetyl-N-{(1R)-1-[3,5-bis(...)
Affinity DataIC50:  9.86E+3nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam substrate by HPLC-MS/MS methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed