Compile Data Set for Download or QSAR
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Found 38 Enz. Inhib. hit(s) with all data for entry = 50032879
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50319926(2-(4-ethylpiperazin-1-yl)-N-(4-(2-morpholino-4-oxo...)
Affinity DataIC50:  5nMAssay Description:Inhibition of DNA-PKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50336025(CHEMBL1669154 | N-(2-(cyclopropylmethoxy)-4-(2-mor...)
Affinity DataIC50:  8nMAssay Description:Inhibition of DNA-PKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50336024(2-morpholino-N-(5-(2-morpholino-4-oxo-4H-chromen-8...)
Affinity DataIC50:  14nMAssay Description:Inhibition of DNA-PKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50156495(8-(dibenzo[b,d]thiophen-4-yl)-2-morpholino-4H-chro...)
Affinity DataIC50:  28nMAssay Description:Inhibition of DNA-PKMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50336025(CHEMBL1669154 | N-(2-(cyclopropylmethoxy)-4-(2-mor...)
Affinity DataIC50:  70nMAssay Description:Inhibition of PI3Kalpha after 80 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50336028(CHEMBL1669157 | N-(2-hydroxy-4-(2-morpholino-4-oxo...)
Affinity DataIC50:  80nMAssay Description:Inhibition of DNA-PKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50336038(CHEMBL1669167 | N-(2-((1-methylcyclobutyl)methoxy)...)
Affinity DataIC50:  110nMAssay Description:Inhibition of DNA-PKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50156495(8-(dibenzo[b,d]thiophen-4-yl)-2-morpholino-4H-chro...)
Affinity DataIC50:  130nMAssay Description:Inhibition of PI3Kalpha after 80 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50336031(CHEMBL1669160 | N-(2-isobutoxy-4-(2-morpholino-4-o...)
Affinity DataIC50:  150nMAssay Description:Inhibition of PI3Kalpha after 80 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50336032(CHEMBL1669161 | N-(2-(allyloxy)-4-(2-morpholino-4-...)
Affinity DataIC50:  150nMAssay Description:Inhibition of PI3Kalpha after 80 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50336036(CHEMBL1669165 | N-(2-(cyclobutylmethoxy)-4-(2-morp...)
Affinity DataIC50:  160nMAssay Description:Inhibition of DNA-PKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50336032(CHEMBL1669161 | N-(2-(allyloxy)-4-(2-morpholino-4-...)
Affinity DataIC50:  170nMAssay Description:Inhibition of DNA-PKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50336031(CHEMBL1669160 | N-(2-isobutoxy-4-(2-morpholino-4-o...)
Affinity DataIC50:  180nMAssay Description:Inhibition of DNA-PKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50336038(CHEMBL1669167 | N-(2-((1-methylcyclobutyl)methoxy)...)
Affinity DataIC50:  270nMAssay Description:Inhibition of PI3Kalpha after 80 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50336029(CHEMBL1669158 | N-(2-ethoxy-4-(2-morpholino-4-oxo-...)
Affinity DataIC50:  280nMAssay Description:Inhibition of DNA-PKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50336036(CHEMBL1669165 | N-(2-(cyclobutylmethoxy)-4-(2-morp...)
Affinity DataIC50:  290nMAssay Description:Inhibition of PI3Kalpha after 80 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50336030(CHEMBL1669159 | N-(2-isopropoxy-4-(2-morpholino-4-...)
Affinity DataIC50:  290nMAssay Description:Inhibition of PI3Kalpha after 80 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50336027(CHEMBL1669156 | N-(2-methoxy-4-(2-morpholino-4-oxo...)
Affinity DataIC50:  290nMAssay Description:Inhibition of DNA-PKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50336026(CHEMBL1669155 | N-(2-((3-methyloxetan-3-yl)methoxy...)
Affinity DataIC50:  300nMAssay Description:Inhibition of PI3Kalpha after 80 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50336030(CHEMBL1669159 | N-(2-isopropoxy-4-(2-morpholino-4-...)
Affinity DataIC50:  330nMAssay Description:Inhibition of DNA-PKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50336027(CHEMBL1669156 | N-(2-methoxy-4-(2-morpholino-4-oxo...)
Affinity DataIC50:  350nMAssay Description:Inhibition of PI3Kalpha after 80 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50336037(CHEMBL1669166 | N-(2-(2-cyclopropylethoxy)-4-(2-mo...)
Affinity DataIC50:  400nMAssay Description:Inhibition of PI3Kalpha after 80 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50336028(CHEMBL1669157 | N-(2-hydroxy-4-(2-morpholino-4-oxo...)
Affinity DataIC50:  430nMAssay Description:Inhibition of PI3Kalpha after 80 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50336029(CHEMBL1669158 | N-(2-ethoxy-4-(2-morpholino-4-oxo-...)
Affinity DataIC50:  470nMAssay Description:Inhibition of PI3Kalpha after 80 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Newcastle University

Curated by ChEMBL
LigandPNGBDBM12915(2-(4-Morpholinyl)-8-phenyl-4H-1-benzopyran-4-one |...)
Affinity DataIC50:  500nMAssay Description:Inhibition of PI3Kalpha after 80 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50336037(CHEMBL1669166 | N-(2-(2-cyclopropylethoxy)-4-(2-mo...)
Affinity DataIC50:  500nMAssay Description:Inhibition of DNA-PKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50336026(CHEMBL1669155 | N-(2-((3-methyloxetan-3-yl)methoxy...)
Affinity DataIC50:  690nMAssay Description:Inhibition of DNA-PKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50336039(CHEMBL1669168 | N-(2-(2-hydroxyethoxy)-4-(2-morpho...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of DNA-PKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50336033(CHEMBL1669162 | N-(2-(2-amino-2-oxoethoxy)-4-(2-mo...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of PI3Kalpha after 80 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
Newcastle University

Curated by ChEMBL
LigandPNGBDBM12915(2-(4-Morpholinyl)-8-phenyl-4H-1-benzopyran-4-one |...)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of DNA-PKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50336034(CHEMBL1669163 | N-(2-(2-methoxyethoxy)-4-(2-morpho...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of PI3Kalpha after 80 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50336039(CHEMBL1669168 | N-(2-(2-hydroxyethoxy)-4-(2-morpho...)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of PI3Kalpha after 80 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50336034(CHEMBL1669163 | N-(2-(2-methoxyethoxy)-4-(2-morpho...)
Affinity DataIC50:  2.60E+3nMAssay Description:Inhibition of DNA-PKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50336040(CHEMBL1669169 | N-(2-(2-aminoethoxy)-4-(2-morpholi...)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of PI3Kalpha after 80 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50336033(CHEMBL1669162 | N-(2-(2-amino-2-oxoethoxy)-4-(2-mo...)
Affinity DataIC50:  3.30E+3nMAssay Description:Inhibition of DNA-PKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50336035(2-morpholino-N-(4-(2-morpholino-4-oxo-4H-chromen-8...)
Affinity DataIC50:  4.40E+3nMAssay Description:Inhibition of PI3Kalpha after 80 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50336035(2-morpholino-N-(4-(2-morpholino-4-oxo-4H-chromen-8...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of DNA-PKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50336040(CHEMBL1669169 | N-(2-(2-aminoethoxy)-4-(2-morpholi...)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibition of DNA-PKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed