Compile Data Set for Download or QSAR
maximum 50k data
Found 22 Enz. Inhib. hit(s) with all data for entry = 50032987
TargetProthrombin(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50337483(CHEMBL1682777 | N1-(5-chloro-2-(1H-tetrazol-1-yl)b...)
Affinity DataKi:  0.270nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50337479(CHEMBL1682781 | N-(5-chloro-2-(1H-tetrazol-1-yl)be...)
Affinity DataKi:  0.270nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50337485(CHEMBL1682775 | N1-(2-(aminomethyl)-5-chlorobenzyl...)
Affinity DataKi:  0.680nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50337487(CHEMBL1682773 | methyl 2-(4-chloro-2-(2-(3-(diisob...)
Affinity DataKi:  0.730nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50337478(3-(3-(5-chloro-2-(1H-tetrazol-1-yl)benzylcarbamoyl...)
Affinity DataKi:  0.770nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50337488(3-(5-chloro-2-(1H-1,2,4-triazol-1-yl)phenethoxy)-N...)
Affinity DataKi:  0.930nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50337474(CHEMBL1682786 | N-(5-chloro-2-(1H-tetrazol-1-yl)be...)
Affinity DataKi:  0.930nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50337472(CHEMBL1682788 | N-(5-chloro-2-(1H-tetrazol-1-yl)be...)
Affinity DataKi:  1.25nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50337473(3-((2-aminoethyl)(cyclohexyl)amino)-N-(5-chloro-2-...)
Affinity DataKi:  1.60nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50337486(3-(5-chloro-2-(2-oxo-2-(piperidin-3-ylamino)ethoxy...)
Affinity DataKi:  1.60nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50337489(3-(2-(1H-tetrazol-1-yl)phenethoxy)-N,N-diisobutyl-...)
Affinity DataKi:  1.70nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50337477(CHEMBL1682783 | N-(5-chloro-2-(1H-tetrazol-1-yl)be...)
Affinity DataKi:  1.80nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50337491(3-(2-(aminomethyl)phenethoxy)-N,N-diisobutyl-5-met...)
Affinity DataKi:  2.90nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50337493(CHEMBL1682767 | N,N-diisobutyl-3-methyl-5-(2-(5-me...)
Affinity DataKi:  3.5nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50337475(CHEMBL1682785 | N-(5-chloro-2-(1H-tetrazol-1-yl)be...)
Affinity DataKi:  4.10nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50337484(CHEMBL1682776 | N1-(5-chloro-2-(1H-1,2,4-triazol-1...)
Affinity DataKi:  7nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50337476(CHEMBL1682784 | N-(5-chloro-2-(1H-tetrazol-1-yl)be...)
Affinity DataKi:  9.60nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50337490(3-(5-chloro-2-methoxyphenethoxy)-N,N-diisobutyl-5-...)
Affinity DataKi:  34nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50337492(3-(2,2-difluoro-2-(4-methylpyridin-2-yl)ethoxy)-N,...)
Affinity DataKi:  37nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50337482(CHEMBL1682778 | N1-(2-(1H-tetrazol-1-yl)benzyl)-N3...)
Affinity DataKi:  50nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50337481(CHEMBL1682779 | N-(5-chloro-2-(1H-tetrazol-1-yl)be...)
Affinity DataKi:  67nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50337480(3-(4-acetylpyridin-3-yl)-N-(5-chloro-2-(1H-tetrazo...)
Affinity DataKi:  85nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed