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Found 13 Enz. Inhib. hit(s) with all data for entry = 50033173
TargetXanthine dehydrogenase/oxidase(Homo sapiens (Human))
Kaohsiung Medical University

Curated by ChEMBL
LigandPNGBDBM35440(ALLOPURINOL | MLS000069453 | SMR000059083 | cid_20...)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of xanthine oxidase activity assessed as uric acid formation pretreated for 15 mins before substrate addition measured after 5 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetXanthine dehydrogenase/oxidase(Homo sapiens (Human))
Kaohsiung Medical University

Curated by ChEMBL
LigandPNGBDBM50340832(3-[3-(Piperidin-1-yl)-propoxy]xanthone | CHEMBL176...)
Affinity DataIC50:  3.78E+4nMAssay Description:Inhibition of xanthine oxidase activity assessed as uric acid formation pretreated for 15 mins before substrate addition measured after 5 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetXanthine dehydrogenase/oxidase(Homo sapiens (Human))
Kaohsiung Medical University

Curated by ChEMBL
LigandPNGBDBM50340843(3-Hydroxy-6-[3-(methylpiperazylamino)-propoxy]xant...)
Affinity DataIC50:  4.43E+4nMAssay Description:Inhibition of xanthine oxidase activity assessed as uric acid formation pretreated for 15 mins before substrate addition measured after 5 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetXanthine dehydrogenase/oxidase(Homo sapiens (Human))
Kaohsiung Medical University

Curated by ChEMBL
LigandPNGBDBM50340834(3-[3-(4-Methylpiperazino)-propoxy]xanthone | CHEMB...)
Affinity DataIC50:  4.73E+4nMAssay Description:Inhibition of xanthine oxidase activity assessed as uric acid formation pretreated for 15 mins before substrate addition measured after 5 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetXanthine dehydrogenase/oxidase(Homo sapiens (Human))
Kaohsiung Medical University

Curated by ChEMBL
LigandPNGBDBM50340841(3-[3-(Diethylamino)-propoxy]-6-hydroxyxanthone | C...)
Affinity DataIC50:  5.35E+4nMAssay Description:Inhibition of xanthine oxidase activity assessed as uric acid formation pretreated for 15 mins before substrate addition measured after 5 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetXanthine dehydrogenase/oxidase(Homo sapiens (Human))
Kaohsiung Medical University

Curated by ChEMBL
LigandPNGBDBM50340836(3-[3-(Diethylamino)-propoxy]xanthone | CHEMBL17612...)
Affinity DataIC50:  5.65E+4nMAssay Description:Inhibition of xanthine oxidase activity assessed as uric acid formation pretreated for 15 mins before substrate addition measured after 5 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetXanthine dehydrogenase/oxidase(Homo sapiens (Human))
Kaohsiung Medical University

Curated by ChEMBL
LigandPNGBDBM50340839(3-[3-(Cyclopropylamino)-propoxy]-6-hydroxyxanthone...)
Affinity DataIC50:  6.30E+4nMAssay Description:Inhibition of xanthine oxidase activity assessed as uric acid formation pretreated for 15 mins before substrate addition measured after 5 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetXanthine dehydrogenase/oxidase(Homo sapiens (Human))
Kaohsiung Medical University

Curated by ChEMBL
LigandPNGBDBM50340833(3-[3-(Pyrrolidin-1-yl)-propoxy]xanthone | CHEMBL17...)
Affinity DataIC50:  6.55E+4nMAssay Description:Inhibition of xanthine oxidase activity assessed as uric acid formation pretreated for 15 mins before substrate addition measured after 5 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetXanthine dehydrogenase/oxidase(Homo sapiens (Human))
Kaohsiung Medical University

Curated by ChEMBL
LigandPNGBDBM50340838(3-Hydroxy-6-[3-(pyrrolidin-1-yl)-propoxy]xanthone ...)
Affinity DataIC50:  6.88E+4nMAssay Description:Inhibition of xanthine oxidase activity assessed as uric acid formation pretreated for 15 mins before substrate addition measured after 5 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetXanthine dehydrogenase/oxidase(Homo sapiens (Human))
Kaohsiung Medical University

Curated by ChEMBL
LigandPNGBDBM50340840(3-[3-(Cyclohexylamino)-propoxy]-6-hydroxyxanthone ...)
Affinity DataIC50:  7.29E+4nMAssay Description:Inhibition of xanthine oxidase activity assessed as uric acid formation pretreated for 15 mins before substrate addition measured after 5 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetXanthine dehydrogenase/oxidase(Homo sapiens (Human))
Kaohsiung Medical University

Curated by ChEMBL
LigandPNGBDBM50340837(3-Hydroxy-6-[3-(piperidin-1-yl)-propoxy]xanthone |...)
Affinity DataIC50:  8.23E+4nMAssay Description:Inhibition of xanthine oxidase activity assessed as uric acid formation pretreated for 15 mins before substrate addition measured after 5 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetXanthine dehydrogenase/oxidase(Homo sapiens (Human))
Kaohsiung Medical University

Curated by ChEMBL
LigandPNGBDBM50340842(3-Hydroxy-6-[3-(piperazino)-propoxy]xanthone | CHE...)
Affinity DataIC50:  9.19E+4nMAssay Description:Inhibition of xanthine oxidase activity assessed as uric acid formation pretreated for 15 mins before substrate addition measured after 5 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetXanthine dehydrogenase/oxidase(Homo sapiens (Human))
Kaohsiung Medical University

Curated by ChEMBL
LigandPNGBDBM50340835(3-[3-(Piperazino)-propoxy]xanthone | CHEMBL1761211)
Affinity DataIC50:  1.09E+5nMAssay Description:Inhibition of xanthine oxidase activity assessed as uric acid formation pretreated for 15 mins before substrate addition measured after 5 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed