Compile Data Set for Download or QSAR
maximum 50k data
Found 87 Enz. Inhib. hit(s) with all data for entry = 50001148
LigandPNGBDBM50013184(1H-Indole-2-carboxylic acid [5-(2-fluoro-phenyl)-1...)
Affinity DataIC50:  0.300nMAssay Description:Displacement of [3H]dihydromorphine (DHM) from rat brain Opioid receptorsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50013209(4-Chloro-N-[5-(2-fluoro-phenyl)-1-methyl-2,3-dihyd...)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of binding of [125I]-CCK-8 to Cholecystokinin type A receptor in rat pancreasMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50452659(CHEMBL304546)
Affinity DataIC50:  1.10nMAssay Description:Evaluated for its concentration required for displacement of [3H]-Naloxone from opioid receptors in rat brain tissuesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50013185(2-Benzo[b]thiophen-4-yl-N-[5-(2-fluoro-phenyl)-1-m...)
Affinity DataIC50:  3nMAssay Description:Displacement of [3H]dihydromorphine (DHM) from rat brain Opioid receptorsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50013208(CHEMBL337530 | N-[5-(2-Fluoro-phenyl)-1-methyl-2,3...)
Affinity DataIC50:  7nMAssay Description:Inhibition of binding of [125I]-CCK-8 to Cholecystokinin type B receptor in guinea pig brain tissuesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(RAT)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50005463((R)-1H-Indole-2-carboxylic acid (1-methyl-2-oxo-5-...)
Affinity DataIC50:  8nMAssay Description:Inhibition of binding of [125I]-CCK-8 to Cholecystokinin type A receptor in rat pancreasMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50013182(1H-Indole-2-carboxylic acid [5-(2-fluoro-phenyl)-2...)
Affinity DataIC50:  8.60nMAssay Description:Evaluated for its concentration required for displacement of [3H]-Naloxone from opioid receptors in rat brain tissuesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50013191(3-{[5-(2-Fluoro-phenyl)-1-methyl-2,3-dihydro-1H-be...)
Affinity DataIC50:  18nMAssay Description:Displacement of [3H]dihydromorphine (DHM) from rat brain Opioid receptorsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(RAT)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50013191(3-{[5-(2-Fluoro-phenyl)-1-methyl-2,3-dihydro-1H-be...)
Affinity DataIC50:  18nMAssay Description:Inhibition of binding of [125I]-CCK-8 to Cholecystokinin type A receptor in rat pancreasMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50013199(CHEMBL342415 | N-[5-(2-Fluoro-phenyl)-1-methyl-2,3...)
Affinity DataIC50:  22nMAssay Description:Displacement of [3H]dihydromorphine (DHM) from rat brain Opioid receptorsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(RAT)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50452659(CHEMBL304546)
Affinity DataIC50:  29nMAssay Description:Inhibition of binding of [125I]-CCK-8 to Cholecystokinin type A receptor in rat pancreasMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50013195(CHEMBL140749 | Thiophene-3-carboxylic acid [5-(2-f...)
Affinity DataIC50:  30nMAssay Description:Displacement of [3H]dihydromorphine (DHM) from rat brain Opioid receptorsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50013188(2-Amino-N-[5-(2-fluoro-phenyl)-1-methyl-2,3-dihydr...)
Affinity DataIC50:  40nMAssay Description:Displacement of [3H]dihydromorphine (DHM) from rat brain Opioid receptorsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(RAT)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50049805(CHEMBL169703 | Thiophene-3-carboxylic acid [5-(2-f...)
Affinity DataIC50:  47nMAssay Description:Inhibition of binding of [125I]-CCK-8 to Cholecystokinin type A receptor in rat pancreasMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50452658(CHEMBL68870)
Affinity DataIC50:  50nMAssay Description:Displacement of [3H]dihydromorphine (DHM) from rat brain Opioid receptorsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50013192(CHEMBL140495 | [5-(2-Fluoro-phenyl)-2,3-dihydro-1H...)
Affinity DataIC50:  91nMAssay Description:Evaluated for its concentration required for displacement of [3H]-Naloxone from opioid receptors in rat brain tissuesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50013204(CHEMBL343158 | Thiophene-3-carboxylic acid [5-(2-f...)
Affinity DataIC50:  93nMAssay Description:Evaluated for its concentration required for displacement of [3H]-Naloxone from opioid receptors in rat brain tissuesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50013205(2-(Acetylamino-methylsulfanyl)-N-[5-(2-fluoro-phen...)
Affinity DataIC50:  120nMAssay Description:Displacement of [3H]dihydromorphine (DHM) from rat brain Opioid receptorsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(RAT)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50013184(1H-Indole-2-carboxylic acid [5-(2-fluoro-phenyl)-1...)
Affinity DataIC50:  160nMAssay Description:Inhibition of binding of [125I]-CCK-8 to Cholecystokinin type A receptor in rat pancreasMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50005463((R)-1H-Indole-2-carboxylic acid (1-methyl-2-oxo-5-...)
Affinity DataIC50:  245nMAssay Description:Inhibition of binding of [125I]-CCK-8 to Cholecystokinin type B receptor in guinea pig brain tissuesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(RAT)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50452658(CHEMBL68870)
Affinity DataIC50:  260nMAssay Description:Inhibition of binding of [125I]-CCK-8 to Cholecystokinin type A receptor in rat pancreasMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(RAT)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50013185(2-Benzo[b]thiophen-4-yl-N-[5-(2-fluoro-phenyl)-1-m...)
Affinity DataIC50:  450nMAssay Description:Inhibition of binding of [125I]-CCK-8 to Cholecystokinin type A receptor in rat pancreasMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50013197(CHEMBL140620 | N-[5-(2-Fluoro-phenyl)-1-methyl-2,3...)
Affinity DataIC50:  450nMAssay Description:Displacement of [3H]dihydromorphine (DHM) from rat brain Opioid receptorsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50013203(1H-Indole-2-carboxylic acid [5-(2-fluoro-phenyl)-2...)
Affinity DataIC50:  540nMAssay Description:Evaluated for its concentration required for displacement of [3H]-Naloxone from opioid receptors in rat brain tissuesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(RAT)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50013208(CHEMBL337530 | N-[5-(2-Fluoro-phenyl)-1-methyl-2,3...)
Affinity DataIC50:  600nMAssay Description:Inhibition of binding of [125I]-CCK-8 to Cholecystokinin type A receptor in rat pancreasMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(RAT)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50013209(4-Chloro-N-[5-(2-fluoro-phenyl)-1-methyl-2,3-dihyd...)
Affinity DataIC50:  800nMAssay Description:Inhibition of binding of [125I]-CCK-8 to Cholecystokinin type A receptor in rat pancreasMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(RAT)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50013199(CHEMBL342415 | N-[5-(2-Fluoro-phenyl)-1-methyl-2,3...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of binding of [125I]-CCK-8 to Cholecystokinin type A receptor in rat pancreasMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(RAT)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50013200(CHEMBL141051 | [5-(2-Fluoro-phenyl)-1-methyl-2,3-d...)
Affinity DataIC50:  2.20E+3nMAssay Description:Inhibition of binding of [125I]-CCK-8 to Cholecystokinin type A receptor in rat pancreasMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(RAT)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50013187(2-Fluoro-N-[5-(2-fluoro-phenyl)-1-methyl-2,3-dihyd...)
Affinity DataIC50:  2.90E+3nMAssay Description:Inhibition of binding of [125I]-CCK-8 to Cholecystokinin type A receptor in rat pancreasMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(RAT)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50013182(1H-Indole-2-carboxylic acid [5-(2-fluoro-phenyl)-2...)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of binding of [125I]-CCK-8 to Cholecystokinin type A receptor in rat pancreasMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(RAT)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50013190(CHEMBL342256 | [1-{[5-(2-Fluoro-phenyl)-1-methyl-2...)
Affinity DataIC50:  4.10E+3nMAssay Description:Inhibition of binding of [125I]-CCK-8 to Cholecystokinin type A receptor in rat pancreasMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(RAT)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50013207(2-[5-(2-Fluoro-phenyl)-1-methyl-2,3-dihydro-1H-ben...)
Affinity DataIC50:  4.30E+3nMAssay Description:Inhibition of binding of [125I]-CCK-8 to Cholecystokinin type A receptor in rat pancreasMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(RAT)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50013195(CHEMBL140749 | Thiophene-3-carboxylic acid [5-(2-f...)
Affinity DataIC50:  4.80E+3nMAssay Description:Inhibition of binding of [125I]-CCK-8 to Cholecystokinin type A receptor in rat pancreasMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(RAT)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50013179(CHEMBL336690 | [5-(2-Fluoro-phenyl)-1-methyl-2,3-d...)
Affinity DataIC50:  5.80E+3nMAssay Description:Inhibition of binding of [125I]-CCK-8 to Cholecystokinin type A receptor in rat pancreasMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(RAT)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50013203(1H-Indole-2-carboxylic acid [5-(2-fluoro-phenyl)-2...)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibition of binding of [125I]-CCK-8 to Cholecystokinin type A receptor in rat pancreasMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50013183(CHEMBL140984 | Thiophene-3-carboxylic acid [5-(2-f...)
Affinity DataIC50:  7.50E+3nMAssay Description:Evaluated for its concentration required for displacement of [3H]-Naloxone from opioid receptors in rat brain tissuesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(RAT)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50013186((Diastereomer)-N-[5-(2-Fluoro-phenyl)-2,3-dihydro-...)
Affinity DataIC50:  8.00E+3nMAssay Description:Inhibition of binding of [125I]-CCK-8 to Cholecystokinin type A receptor in rat pancreasMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(RAT)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50013204(CHEMBL343158 | Thiophene-3-carboxylic acid [5-(2-f...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of binding of [125I]-CCK-8 to Cholecystokinin type A receptor in rat pancreasMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(RAT)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50013197(CHEMBL140620 | N-[5-(2-Fluoro-phenyl)-1-methyl-2,3...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of binding of [125I]-CCK-8 to Cholecystokinin type A receptor in rat pancreasMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50005463((R)-1H-Indole-2-carboxylic acid (1-methyl-2-oxo-5-...)
Affinity DataIC50:  1.00E+4nMAssay Description:Evaluated for its concentration required for displacement of [3H]-Naloxone from opioid receptors in rat brain tissuesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(RAT)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50013188(2-Amino-N-[5-(2-fluoro-phenyl)-1-methyl-2,3-dihydr...)
Affinity DataIC50:  1.16E+4nMAssay Description:Inhibition of binding of [125I]-CCK-8 to Cholecystokinin type A receptor in rat pancreasMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50013189(CHEMBL334933 | [5-(2-Fluoro-phenyl)-2-oxo-2,3-dihy...)
Affinity DataIC50:  1.20E+4nMAssay Description:Displacement of [3H]dihydromorphine (DHM) from rat brain Opioid receptorsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(RAT)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50013194(3,3,3-Trifluoro-N-[5-(2-fluoro-phenyl)-1-methyl-2,...)
Affinity DataIC50:  1.30E+4nMAssay Description:Inhibition of binding of [125I]-CCK-8 to Cholecystokinin type A receptor in rat pancreasMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(RAT)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50013196(Bis[5-(2-fluoro-phenyl)-1,3-dihydro-benzo[e][1,4]d...)
Affinity DataIC50:  1.40E+4nMAssay Description:Inhibition of binding of [125I]-CCK-8 to Cholecystokinin type A receptor in rat pancreasMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(RAT)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50013202(3-[(5-Chloro-pyrazin-2-ylamino)-methyl]-5-(2-fluor...)
Affinity DataIC50:  1.50E+4nMAssay Description:Inhibition of binding of [125I]-CCK-8 to Cholecystokinin type A receptor in rat pancreasMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50013184(1H-Indole-2-carboxylic acid [5-(2-fluoro-phenyl)-1...)
Affinity DataIC50:  1.55E+4nMAssay Description:Inhibition of binding of [125I]-CCK-8 to Cholecystokinin type B receptor in guinea pig brain tissuesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(RAT)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50013183(CHEMBL140984 | Thiophene-3-carboxylic acid [5-(2-f...)
Affinity DataIC50:  2.20E+4nMAssay Description:Inhibition of binding of [125I]-CCK-8 to Cholecystokinin type A receptor in rat pancreasMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(RAT)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50013189(CHEMBL334933 | [5-(2-Fluoro-phenyl)-2-oxo-2,3-dihy...)
Affinity DataIC50:  2.20E+4nMAssay Description:Inhibition of binding of [125I]-CCK-8 to Cholecystokinin type A receptor in rat pancreasMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50013185(2-Benzo[b]thiophen-4-yl-N-[5-(2-fluoro-phenyl)-1-m...)
Affinity DataIC50:  2.30E+4nMAssay Description:Inhibition of binding of [125I]-CCK-8 to Cholecystokinin type B receptor in guinea pig brain tissuesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(RAT)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50013181((2-(Acetylamino-methylsulfanyl)-1-{[5-(2-fluoro-ph...)
Affinity DataIC50:  2.40E+4nMAssay Description:Inhibition of binding of [125I]-CCK-8 to Cholecystokinin type A receptor in rat pancreasMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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