Compile Data Set for Download or QSAR
maximum 50k data
Found 113 Enz. Inhib. hit(s) with all data for entry = 50034134
LigandPNGBDBM50357645(CHEMBL1738719)
Affinity DataKi:  0.600nMAssay Description:Inhibition of N-terminus polyHis-tagged human recombinant PI3Kalpha expressed in baculovirus infected insect Sf9 cells using phosphoinositol-4,5-bisp...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50357674(CHEMBL1914739)
Affinity DataKi:  0.600nMAssay Description:Inhibition of N-terminus polyHis-tagged human recombinant PI3Kalpha expressed in baculovirus infected insect Sf9 cells using phosphoinositol-4,5-bisp...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50357652(CHEMBL1914726)
Affinity DataKi:  0.700nMAssay Description:Inhibition of N-terminus polyHis-tagged human recombinant PI3Kalpha expressed in baculovirus infected insect Sf9 cells using phosphoinositol-4,5-bisp...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50357665(CHEMBL1914728)
Affinity DataKi:  0.700nMAssay Description:Inhibition of N-terminus polyHis-tagged human recombinant PI3Kalpha expressed in baculovirus infected insect Sf9 cells using phosphoinositol-4,5-bisp...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50357653(CHEMBL1914727)
Affinity DataKi:  0.800nMAssay Description:Inhibition of N-terminus polyHis-tagged human recombinant PI3Kalpha expressed in baculovirus infected insect Sf9 cells using phosphoinositol-4,5-bisp...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50357670(CHEMBL1914734)
Affinity DataKi:  0.800nMAssay Description:Inhibition of N-terminus polyHis-tagged human recombinant PI3Kalpha expressed in baculovirus infected insect Sf9 cells using phosphoinositol-4,5-bisp...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50357668(CHEMBL1914731)
Affinity DataKi:  0.800nMAssay Description:Inhibition of N-terminus polyHis-tagged human recombinant PI3Kalpha expressed in baculovirus infected insect Sf9 cells using phosphoinositol-4,5-bisp...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50357650(CHEMBL1914742)
Affinity DataKi:  0.800nMAssay Description:Inhibition of N-terminus polyHis-tagged human recombinant PI3Kalpha expressed in baculovirus infected insect Sf9 cells using phosphoinositol-4,5-bisp...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50357651(CHEMBL1914724)
Affinity DataKi:  0.900nMAssay Description:Inhibition of N-terminus polyHis-tagged human recombinant PI3Kalpha expressed in baculovirus infected insect Sf9 cells using phosphoinositol-4,5-bisp...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50357662(CHEMBL1914721)
Affinity DataKi:  0.900nMAssay Description:Inhibition of PI3Kalpha-mediated Akt phosphorylation at Ser 473 in human U87MG cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50357666(CHEMBL1914729)
Affinity DataKi:  0.900nMAssay Description:Inhibition of N-terminus polyHis-tagged human recombinant PI3Kalpha expressed in baculovirus infected insect Sf9 cells using phosphoinositol-4,5-bisp...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50357673(CHEMBL1914738)
Affinity DataKi:  0.900nMAssay Description:Inhibition of N-terminus polyHis-tagged human recombinant PI3Kalpha expressed in baculovirus infected insect Sf9 cells using phosphoinositol-4,5-bisp...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50357675(CHEMBL1914740)
Affinity DataKi:  1nMAssay Description:Inhibition of N-terminus polyHis-tagged human recombinant PI3Kalpha expressed in baculovirus infected insect Sf9 cells using phosphoinositol-4,5-bisp...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50357664(CHEMBL1914723)
Affinity DataKi:  1nMAssay Description:Inhibition of PI3Kalpha-mediated Akt phosphorylation at Ser 473 in human U87MG cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50357667(CHEMBL1914730)
Affinity DataKi:  1nMAssay Description:Inhibition of PI3Kalpha-mediated Akt phosphorylation at Ser 473 in human U87MG cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50357644(CHEMBL1914947)
Affinity DataKi:  1nMAssay Description:Inhibition of N-terminus polyHis-tagged human recombinant PI3Kalpha expressed in baculovirus infected insect Sf9 cells using phosphoinositol-4,5-bisp...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50343200(CHEMBL1615189 | N-(6-(6-Chloro-5-(4-fluorophenylsu...)
Affinity DataKi:  1.20nMAssay Description:Inhibition of PI3Kalpha-mediated Akt phosphorylation at Ser 473 in human U87MG cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50357643(CHEMBL1914725)
Affinity DataKi:  1.30nMAssay Description:Inhibition of N-terminus polyHis-tagged human recombinant PI3Kalpha expressed in baculovirus infected insect Sf9 cells using phosphoinositol-4,5-bisp...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50357669(CHEMBL1914732)
Affinity DataKi:  1.40nMAssay Description:Inhibition of N-terminus polyHis-tagged human recombinant PI3Kalpha expressed in baculovirus infected insect Sf9 cells using phosphoinositol-4,5-bisp...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50357640(CHEMBL1914741)
Affinity DataKi:  1.40nMAssay Description:Inhibition of PI3Kalpha-mediated Akt phosphorylation at Ser 473 in human U87MG cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50357647(CHEMBL1914737)
Affinity DataKi:  1.70nMAssay Description:Inhibition of N-terminus polyHis-tagged human recombinant PI3Kalpha expressed in baculovirus infected insect Sf9 cells using phosphoinositol-4,5-bisp...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50357663(CHEMBL1914722)
Affinity DataKi:  1.80nMAssay Description:Inhibition of PI3Kalpha-mediated Akt phosphorylation at Ser 473 in human U87MG cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50357661(CHEMBL1914720)
Affinity DataKi:  1.90nMAssay Description:Inhibition of N-terminus polyHis-tagged human recombinant PI3Kalpha expressed in baculovirus infected insect Sf9 cells using phosphoinositol-4,5-bisp...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50357641(CHEMBL1914710)
Affinity DataKi:  2.10nMAssay Description:Inhibition of PI3Kalpha-mediated Akt phosphorylation at Ser 473 in human U87MG cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50357648(CHEMBL1914716)
Affinity DataKi:  2.60nMAssay Description:Inhibition of PI3Kalpha-mediated Akt phosphorylation at Ser 473 in human U87MG cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50357671(CHEMBL1914735)
Affinity DataKi:  3.10nMAssay Description:Inhibition of N-terminus polyHis-tagged human recombinant PI3Kalpha expressed in baculovirus infected insect Sf9 cells using phosphoinositol-4,5-bisp...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50357659(CHEMBL1914715)
Affinity DataKi:  3.10nMAssay Description:Inhibition of PI3Kalpha-mediated Akt phosphorylation at Ser 473 in human U87MG cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50357646(CHEMBL1914733)
Affinity DataKi:  3.30nMAssay Description:Inhibition of N-terminus polyHis-tagged human recombinant PI3Kalpha expressed in baculovirus infected insect Sf9 cells using phosphoinositol-4,5-bisp...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50357642(CHEMBL1914712)
Affinity DataKi:  5.10nMAssay Description:Inhibition of PI3Kalpha-mediated Akt phosphorylation at Ser 473 in human U87MG cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50351947(CHEMBL1822052)
Affinity DataKi:  5.60nMAssay Description:Inhibition of N-terminus polyHis-tagged human recombinant PI3Kalpha expressed in baculovirus infected insect Sf9 cells using phosphoinositol-4,5-bisp...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50357649(CHEMBL1914719)
Affinity DataKi:  5.70nMAssay Description:Inhibition of N-terminus polyHis-tagged human recombinant PI3Kalpha expressed in baculovirus infected insect Sf9 cells using phosphoinositol-4,5-bisp...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50351948(CHEMBL1822053)
Affinity DataKi:  13nMAssay Description:Inhibition of N-terminus polyHis-tagged human recombinant PI3Kalpha expressed in baculovirus infected insect Sf9 cells using phosphoinositol-4,5-bisp...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50357660(CHEMBL1914717)
Affinity DataKi:  38nMAssay Description:Inhibition of PI3Kalpha-mediated Akt phosphorylation at Ser 473 in human U87MG cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50357654(CHEMBL1914718)
Affinity DataKi:  69nMAssay Description:Inhibition of PI3Kalpha-mediated Akt phosphorylation at Ser 473 in human U87MG cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50357656(CHEMBL1914713)
Affinity DataKi:  200nMAssay Description:Inhibition of PI3Kalpha-mediated Akt phosphorylation at Ser 473 in human U87MG cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50357655(CHEMBL1914711)
Affinity DataKi:  375nMAssay Description:Inhibition of PI3Kalpha-mediated Akt phosphorylation at Ser 473 in human U87MG cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50357657(CHEMBL1914714)
Affinity DataKi:  856nMAssay Description:Inhibition of PI3Kalpha-mediated Akt phosphorylation at Ser 473 in human U87MG cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50357653(CHEMBL1914727)
Affinity DataIC50:  0.410nMAssay Description:Inhibition of mTOR using GFP-tagged 4E-BP1 after 1 hr by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50357652(CHEMBL1914726)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of mTOR using GFP-tagged 4E-BP1 after 1 hr by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50357645(CHEMBL1738719)
Affinity DataIC50:  2.30nMAssay Description:Inhibition of DNA-PK using fluorescein-p53 peptide as substrate after 1 hr by TR-FRET enzyme assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50357658(CHEMBL1914743)
Affinity DataIC50:  2.40nMAssay Description:Inhibition of N-terminus polyHis-tagged human recombinant PI3Kgamma expressed in baculovirus infected insect Sf9 cells using phosphoinositol-4,5-bisp...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50357652(CHEMBL1914726)
Affinity DataIC50:  2.90nMAssay Description:Inhibition of human VPS34 assessed as ADP formation using ATP by fluorescence-based immunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50357658(CHEMBL1914743)
Affinity DataIC50:  3.10nMAssay Description:Inhibition of PI3Kalpha-mediated Akt phosphorylation at Ser 473 in human U87MG cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50357658(CHEMBL1914743)
Affinity DataIC50:  3.10nMAssay Description:Inhibition of N-terminus polyHis-tagged human recombinant PI3Kalpha expressed in baculovirus infected insect Sf9 cells using phosphoinositol-4,5-bisp...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50357658(CHEMBL1914743)
Affinity DataIC50:  3.40nMAssay Description:Inhibition of DNA-PK using fluorescein-p53 peptide as substrate after 1 hr by TR-FRET enzyme assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50357653(CHEMBL1914727)
Affinity DataIC50:  3.70nMAssay Description:Inhibition of PI3Kalpha-mediated Akt phosphorylation at Ser 473 in human U87MG cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50357645(CHEMBL1738719)
Affinity DataIC50:  3.90nMAssay Description:Inhibition of mTOR using GFP-tagged 4E-BP1 after 1 hr by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50357651(CHEMBL1914724)
Affinity DataIC50:  3.90nMAssay Description:Inhibition of mTOR using GFP-tagged 4E-BP1 after 1 hr by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50357645(CHEMBL1738719)
Affinity DataIC50:  4.30nMAssay Description:Inhibition of N-terminus polyHis-tagged human recombinant PI3Kdelta expressed in baculovirus infected insect Sf9 cells using phosphoinositol-4,5-bisp...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50357658(CHEMBL1914743)
Affinity DataIC50:  4.40nMAssay Description:Inhibition of N-terminus polyHis-tagged human recombinant PI3Kdelta expressed in baculovirus infected insect Sf9 cells using phosphoinositol-4,5-bisp...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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