Affinity DataKi: 0.0450nMAssay Description:Antagonist activity at human bradykinin B1 receptor expressed in human HEK293 cells assessed as calcium flux by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.300nMAssay Description:Displacement of radioligand from human adrenergic beta2 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 9nMAssay Description:Displacement of radioligand from human adrenergic beta2 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 18nMAssay Description:Displacement of radioligand from human adenosine A2A receptorMore data for this Ligand-Target Pair
Affinity DataKi: 32nMAssay Description:Displacement of radioligand from human adenosine A2A receptorMore data for this Ligand-Target Pair
Affinity DataKi: 200nMAssay Description:Displacement of radioligand from human adenosine A2A receptorMore data for this Ligand-Target Pair
Affinity DataKi: 470nMAssay Description:Displacement of radioligand from human adrenergic beta2 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 815nMAssay Description:Antagonist activity at human bradykinin B1 receptor expressed in human HEK293 cells assessed as calcium flux by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.160nMAssay Description:Agonist activity at human adrenergic beta3 receptor by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataEC50: 380nMAssay Description:Agonist activity at GPR109aMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Heptares Therapeutics
Curated by ChEMBL
Heptares Therapeutics
Curated by ChEMBL
Affinity DataEC50: 400nMAssay Description:Agonist activity at human M1 muscarinic receptor expressed in CHO cells assessed as inhibition of carbachol-stimulated phosphatidyl-inositol hydrolys...More data for this Ligand-Target Pair
Affinity DataKd: 100nMAssay Description:Binding affinity to human adrenergic beta2 receptor by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataEC50: 1.25E+4nMAssay Description:Agonist activity at GPR109aMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Heptares Therapeutics
Curated by ChEMBL
Heptares Therapeutics
Curated by ChEMBL
Affinity DataEC50: 8nMAssay Description:Agonist activity at human M1 muscarinic receptor expressed in CHO cells assessed as inhibition of carbachol-stimulated phosphatidyl-inositol hydrolys...More data for this Ligand-Target Pair