Compile Data Set for Download or QSAR
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Found 6 Enz. Inhib. hit(s) with all data for entry = 50033737
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Rwth Aachen University

Curated by ChEMBL
LigandPNGBDBM17638(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)
Affinity DataIC50:  34nMAssay Description:Inhibition of human platelets COX1 assessed as PGE2 production using arachidonic acid as substrate preincubated for 15 mins measured after 15 mins by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Rwth Aachen University

Curated by ChEMBL
LigandPNGBDBM50350507(CHEMBL1814813)
Affinity DataIC50:  42nMAssay Description:Inhibition of human platelets COX1 assessed as PGE2 production using arachidonic acid as substrate preincubated for 15 mins measured after 15 mins by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Rwth Aachen University

Curated by ChEMBL
LigandPNGBDBM22369(4-(4-methanesulfonylphenyl)-3-phenyl-2,5-dihydrofu...)
Affinity DataIC50:  156nMAssay Description:Inhibition of human recombinant COX2 expressed in Sf21 cells assessed as PGE2 production using arachidonic acid as substrate preincubated for 15 mins...More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Rwth Aachen University

Curated by ChEMBL
LigandPNGBDBM50350507(CHEMBL1814813)
Affinity DataIC50:  156nMAssay Description:Inhibition of human recombinant COX2 expressed in Sf21 cells assessed as PGE2 production using arachidonic acid as substrate preincubated for 15 mins...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Rwth Aachen University

Curated by ChEMBL
LigandPNGBDBM50419031(CHEMBL2029168)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human ERG expressed in HEK293 cells assessed as inhibition of tail current at holding potential of -70 mV after 10 mins by whole-cell p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Rwth Aachen University

Curated by ChEMBL
LigandPNGBDBM50350507(CHEMBL1814813)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human ERG expressed in HEK293 cells assessed as inhibition of tail current at holding potential of -70 mV after 10 mins by whole-cell p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed