Found 32 Enz. Inhib. hit(s) with all data for entry = 50039728 
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of human CYP2C19More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human CYP2D6More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human CYP3A4More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human CYP1A2More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human CYP2C9More data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Ambit Biosciences
Curated by ChEMBL
Ambit Biosciences
Curated by ChEMBL
Affinity DataKd: 9nMAssay Description:Inhibition of CSF1R in human HEK293 cells after 1 hr by competition binding assayMore data for this Ligand-Target Pair
Affinity DataKd: >1.00E+4nMAssay Description:Inhibition of Aurora A in human HEK293 cells after 1 hr by competition binding assayMore data for this Ligand-Target Pair
Affinity DataKd: >1.00E+4nMAssay Description:Inhibition of ALK in human HEK293 cells after 1 hr by competition binding assayMore data for this Ligand-Target Pair
Affinity DataKd: 3nMAssay Description:Inhibition of Abl1 in human HEK293 cells after 1 hr by competition binding assayMore data for this Ligand-Target Pair
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Ambit Biosciences
Curated by ChEMBL
Ambit Biosciences
Curated by ChEMBL
Affinity DataKd: 39nMAssay Description:Inhibition of CRAF in human HEK293 cells after 1 hr by competition binding assayMore data for this Ligand-Target Pair
Affinity DataKd: 36nMAssay Description:Inhibition of wild type BRAF in human HEK293 cells after 1 hr by competition binding assayMore data for this Ligand-Target Pair
Affinity DataKd: >1.00E+4nMAssay Description:Inhibition of INSR in human HEK293 cells after 1 hr by competition binding assayMore data for this Ligand-Target Pair
Affinity DataKd: >1.00E+4nMAssay Description:Inhibition of JAK1 in human HEK293 cells after 1 hr by competition binding assayMore data for this Ligand-Target Pair
Affinity DataKd: 4.70E+3nMAssay Description:Inhibition of JAK2 in human HEK293 cells after 1 hr by competition binding assayMore data for this Ligand-Target Pair
Affinity DataKd: >1.00E+4nMAssay Description:Inhibition of JAK3 in human HEK293 cells after 1 hr by competition binding assayMore data for this Ligand-Target Pair
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Ambit Biosciences
Curated by ChEMBL
Ambit Biosciences
Curated by ChEMBL
Affinity DataKd: 2nMAssay Description:Inhibition of cKit in human HEK293 cells after 1 hr by competition binding assayMore data for this Ligand-Target Pair
Affinity DataKd: 2nMAssay Description:Inhibition of LCK in human HEK293 cells after 1 hr by competition binding assayMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Ambit Biosciences
Curated by ChEMBL
Ambit Biosciences
Curated by ChEMBL
Affinity DataKd: 7.10E+3nMAssay Description:Inhibition of MEK1 in human HEK293 cells after 1 hr by competition binding assayMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 2(Homo sapiens (Human))
Ambit Biosciences
Curated by ChEMBL
Ambit Biosciences
Curated by ChEMBL
Affinity DataKd: 8.30E+3nMAssay Description:Inhibition of MEK2 in human HEK293 cells after 1 hr by competition binding assayMore data for this Ligand-Target Pair
Affinity DataKd: 513nMAssay Description:Inhibition of cMET in human HEK293 cells after 1 hr by competition binding assayMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Ambit Biosciences
Curated by ChEMBL
Ambit Biosciences
Curated by ChEMBL
Affinity DataKd: 2nMAssay Description:Inhibition of PDGFRbeta in human HEK293 cells after 1 hr by competition binding assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Ambit Biosciences
Curated by ChEMBL
Ambit Biosciences
Curated by ChEMBL
Affinity DataKd: >1.00E+4nMAssay Description:Inhibition of PIK3-CA in human HEK293 cells after 1 hr by competition binding assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Homo sapiens (Human))
Ambit Biosciences
Curated by ChEMBL
Ambit Biosciences
Curated by ChEMBL
Affinity DataKd: >1.00E+4nMAssay Description:Inhibition of PIK3-CB in human HEK293 cells after 1 hr by competition binding assayMore data for this Ligand-Target Pair
Affinity DataKd: >1.00E+4nMAssay Description:Inhibition of PLK1 in human HEK293 cells after 1 hr by competition binding assayMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Ambit Biosciences
Curated by ChEMBL
Ambit Biosciences
Curated by ChEMBL
Affinity DataKd: 2nMAssay Description:Inhibition of Ret in human HEK293 cells after 1 hr by competition binding assayMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Ambit Biosciences
Curated by ChEMBL
Ambit Biosciences
Curated by ChEMBL
Affinity DataKd: 8nMAssay Description:Inhibition of VEGFR2 in human HEK293 cells after 1 hr by competition binding assayMore data for this Ligand-Target Pair
Affinity DataKd: 22nMAssay Description:Inhibition of EGFR in human HEK293 cells after 1 hr by competition binding assayMore data for this Ligand-Target Pair
Affinity DataKd: 14nMAssay Description:Inhibition of EPHA2 in human HEK293 cells after 1 hr by competition binding assayMore data for this Ligand-Target Pair
Affinity DataKd: >1.00E+4nMAssay Description:Inhibition of ERK1 in human HEK293 cells after 1 hr by competition binding assayMore data for this Ligand-Target Pair
Affinity DataKd: >1.00E+4nMAssay Description:Inhibition of ERK2 in human HEK293 cells after 1 hr by competition binding assayMore data for this Ligand-Target Pair
Affinity DataKd: >1.00E+4nMAssay Description:Inhibition of Aurora B in human HEK293 cells after 1 hr by competition binding assayMore data for this Ligand-Target Pair
Affinity DataKd: >1.00E+4nMAssay Description:Inhibition of IGFR1 in human HEK293 cells after 1 hr by competition binding assayMore data for this Ligand-Target Pair
