Compile Data Set for Download or QSAR
maximum 50k data
Found 21 Enz. Inhib. hit(s) with all data for entry = 50040639
TargetCalcium-dependent protein kinase 4(Plasmodium falciparum (isolate 3D7))
Montclair State University

Curated by ChEMBL
LigandPNGBDBM50383381(CHEMBL2030554 | CHEMBL2070050 | US10544104, Compou...)
Affinity DataIC50:  4nMAssay Description:Inhibition of CDPK4 in Plasmodium falciparum 3D7 microgametesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCell division related protein kinase 2(Leishmania major)
Montclair State University

Curated by ChEMBL
LigandPNGBDBM50397589(CHEMBL2171517)
Affinity DataIC50:  5nMAssay Description:Inhibition of Leishmania major CRK3 expressed in Escherichia coli BL21 (DE3) using 5FAM-GGGRSPGRRRRK-OH as substrate after 60 mins by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-dependent protein kinase(Plasmodium falciparum)
Montclair State University

Curated by ChEMBL
LigandPNGBDBM50168171(4-(2-(4-fluorophenyl)-5-(1-methylpiperidin-4-yl)-1...)
Affinity DataIC50:  8nMAssay Description:Inhibition of PKG in Plasmodium falciparum 3D7 microgametesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Montclair State University

Curated by ChEMBL
LigandPNGBDBM92862(US9284315, BEZ-235 | mTOR Inhibitor, BEZ235)
Affinity DataIC50: <10nMAssay Description:Inhibition of PI3KgammaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Montclair State University

Curated by ChEMBL
LigandPNGBDBM92862(US9284315, BEZ-235 | mTOR Inhibitor, BEZ235)
Affinity DataIC50: <10nMAssay Description:Inhibition of PI3KdeltaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Homo sapiens (Human))
Montclair State University

Curated by ChEMBL
LigandPNGBDBM92862(US9284315, BEZ-235 | mTOR Inhibitor, BEZ235)
Affinity DataIC50: <10nMAssay Description:Inhibition of PI3KbetaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Montclair State University

Curated by ChEMBL
LigandPNGBDBM92862(US9284315, BEZ-235 | mTOR Inhibitor, BEZ235)
Affinity DataIC50: <10nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Montclair State University

Curated by ChEMBL
LigandPNGBDBM92862(US9284315, BEZ-235 | mTOR Inhibitor, BEZ235)
Affinity DataIC50: <10nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCell division related protein kinase 2(Leishmania major)
Montclair State University

Curated by ChEMBL
LigandPNGBDBM50397590(CHEMBL2171516)
Affinity DataIC50:  20nMAssay Description:Inhibition of Leishmania major CRK3 expressed in Escherichia coli BL21 (DE3) using 5FAM-GGGRSPGRRRRK-OH as substrate after 60 mins by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCell division related protein kinase 2(Leishmania major)
Montclair State University

Curated by ChEMBL
LigandPNGBDBM50397588(CHEMBL2171518)
Affinity DataIC50:  60nMAssay Description:Inhibition of Leishmania major CRK3 expressed in Escherichia coli BL21 (DE3) using 5FAM-GGGRSPGRRRRK-OH as substrate after 60 mins by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcium-dependent protein kinase 4(Plasmodium falciparum (isolate 3D7))
Montclair State University

Curated by ChEMBL
LigandPNGBDBM50345704(1-(tert-butyl)-3-(naphthalen-2-yl)-1H-pyrazolo[3,4...)
Affinity DataIC50:  177nMAssay Description:Inhibition of CDPK4 in Plasmodium falciparum 3D7 microgametesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCell division related protein kinase 2(Leishmania major)
Montclair State University

Curated by ChEMBL
LigandPNGBDBM50397592(CHEMBL2171514)
Affinity DataIC50:  240nMAssay Description:Inhibition of Leishmania major CRK3 expressed in Escherichia coli BL21 (DE3) using 5FAM-GGGRSPGRRRRK-OH as substrate after 60 mins by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCell division related protein kinase 2(Leishmania major)
Montclair State University

Curated by ChEMBL
LigandPNGBDBM50397593(CHEMBL2171513)
Affinity DataIC50:  260nMAssay Description:Inhibition of Leishmania major CRK3 expressed in Escherichia coli BL21 (DE3) using 5FAM-GGGRSPGRRRRK-OH as substrate after 60 mins by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCell division related protein kinase 2(Leishmania major)
Montclair State University

Curated by ChEMBL
LigandPNGBDBM50397591(CHEMBL2171515)
Affinity DataIC50:  510nMAssay Description:Inhibition of Leishmania major CRK3 expressed in Escherichia coli BL21 (DE3) using 5FAM-GGGRSPGRRRRK-OH as substrate after 60 mins by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCell division related protein kinase 2(Leishmania major)
Montclair State University

Curated by ChEMBL
LigandPNGBDBM47658(1-(4-methylphenyl)-3-(2-pyridin-3-ylpyrimidin-4-yl...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of Leishmania major CRK3 expressed in Escherichia coli BL21 (DE3) using 5FAM-GGGRSPGRRRRK-OH as substrate after 60 mins by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCell division related protein kinase 2(Leishmania major)
Montclair State University

Curated by ChEMBL
LigandPNGBDBM50397595(CHEMBL2171512)
Affinity DataIC50:  5.30E+3nMAssay Description:Inhibition of Leishmania major CRK3 expressed in Escherichia coli BL21 (DE3) using 5FAM-GGGRSPGRRRRK-OH as substrate after 60 mins by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCell division related protein kinase 2(Leishmania major)
Montclair State University

Curated by ChEMBL
LigandPNGBDBM78336((6E)-6-[4-(3-pyridinylmethylamino)-1H-quinazolin-2...)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibition of Leishmania major CRK3 expressed in Escherichia coli BL21 (DE3) using 5FAM-GGGRSPGRRRRK-OH as substrate after 60 mins by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Montclair State University

Curated by ChEMBL
LigandPNGBDBM50321461(2-bromo-N-(2,5-dichlorothiophen-3-ylsulfonyl)-N-ph...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of human CDK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Montclair State University

Curated by ChEMBL
LigandPNGBDBM50321461(2-bromo-N-(2,5-dichlorothiophen-3-ylsulfonyl)-N-ph...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of human CDK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 6(Homo sapiens (Human))
Montclair State University

Curated by ChEMBL
LigandPNGBDBM50321461(2-bromo-N-(2,5-dichlorothiophen-3-ylsulfonyl)-N-ph...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of human CDK6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 7(Homo sapiens (Human))
Montclair State University

Curated by ChEMBL
LigandPNGBDBM50321461(2-bromo-N-(2,5-dichlorothiophen-3-ylsulfonyl)-N-ph...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of human CDK7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed