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Found 35 Enz. Inhib. hit(s) with all data for entry = 50042829
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
East China University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50431812(CHEMBL2347053)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of PDGFRbeta (unknown origin) after 10 mins by mobility shift assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosomal protein S6 kinase beta-1(Homo sapiens (Human))
East China University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50431812(CHEMBL2347053)
Affinity DataIC50:  0.75nMAssay Description:Inhibition of p70S6K (unknown origin) after 10 mins by mobility shift assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(Homo sapiens (Human))
East China University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50431812(CHEMBL2347053)
Affinity DataIC50:  0.980nMAssay Description:Inhibition of PKC alpha (unknown origin) using PIP2 as substrate after 1 hr by Kinase-Glo assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
East China University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50431812(CHEMBL2347053)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of PDGFRalpha (unknown origin) after 10 mins by mobility shift assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosomal protein S6 kinase alpha-3(Homo sapiens (Human))
East China University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50431812(CHEMBL2347053)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of RSK2 (unknown origin) using AKRRRLSSLRA as substrate after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
East China University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50431812(CHEMBL2347053)
Affinity DataIC50:  2.30nMAssay Description:Inhibition of Aurora B (unknown origin) after 10 mins by mobility shift assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
East China University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50431812(CHEMBL2347053)
Affinity DataIC50:  3.30nMAssay Description:Inhibition of LCK (unknown origin) after 10 mins by mobility shift assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lyn(Homo sapiens (Human))
East China University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50431812(CHEMBL2347053)
Affinity DataIC50:  4nMAssay Description:Inhibition of LYNA (unknown origin) after 10 mins by mobility shift assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosomal protein S6 kinase alpha-5(Homo sapiens (Human))
East China University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50431812(CHEMBL2347053)
Affinity DataIC50:  4nMAssay Description:Inhibition of MSK1 (unknown origin) after 10 mins by mobility shift assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
East China University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50431812(CHEMBL2347053)
Affinity DataIC50:  7.70nMAssay Description:Inhibition of KDR (unknown origin) after 10 mins by mobility shift assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
East China University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50431812(CHEMBL2347053)
Affinity DataIC50:  7.90nMAssay Description:Inhibition of SRC (unknown origin) after 10 mins by mobility shift assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial(Homo sapiens (Human))
East China University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50431812(CHEMBL2347053)
Affinity DataIC50:  8.30nMAssay Description:Inhibition of PDK1 (unknown origin) after 10 mins by mobility shift assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
East China University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50431812(CHEMBL2347053)
Affinity DataIC50:  10nMAssay Description:Inhibition of cKit (unknown origin) after 10 mins by mobility shift assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
East China University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50431812(CHEMBL2347053)
Affinity DataIC50:  11nMAssay Description:Inhibition of p38alpha (unknown origin) after 10 mins by mobility shift assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
East China University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50431812(CHEMBL2347053)
Affinity DataIC50:  11nMAssay Description:Inhibition of AKT1 (unknown origin) after 10 mins by mobility shift assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
East China University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50431812(CHEMBL2347053)
Affinity DataIC50:  12nMAssay Description:Inhibition of FGFR1 (unknown origin) after 10 mins by mobility shift assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
East China University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50431812(CHEMBL2347053)
Affinity DataIC50:  13nMAssay Description:Inhibition of GSK3beta (unknown origin) after 10 mins by mobility shift assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosomal protein S6 kinase alpha-3(Homo sapiens (Human))
East China University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50248765(1-(4-amino-7-(3-hydroxypropyl)-5-p-tolyl-7H-pyrrol...)
Affinity DataIC50:  15nMAssay Description:Inhibition of His6x-tagged RSK2 C-terminal domain (unknown origin) expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
East China University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50431812(CHEMBL2347053)
Affinity DataIC50:  25nMAssay Description:Inhibition of FGFR3 (unknown origin) after 10 mins by mobility shift assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
East China University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50431812(CHEMBL2347053)
Affinity DataIC50:  54nMAssay Description:Inhibition of PIM1 (unknown origin) after 10 mins by mobility shift assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosomal protein S6 kinase alpha-3(Homo sapiens (Human))
East China University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50241294(CHEMBL240954 | SL-0101 | kaempferol 3-O-(3'',4''-d...)
Affinity DataIC50:  89nMAssay Description:Inhibition of GST-fused RSK2 (unknown origin) after 10 to 45 mins by immunoblotting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
East China University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50431812(CHEMBL2347053)
Affinity DataIC50:  109nMAssay Description:Inhibition of c-MET (unknown origin) after 10 mins by mobility shift assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
East China University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50431812(CHEMBL2347053)
Affinity DataIC50:  271nMAssay Description:Inhibition of ABL (unknown origin) after 10 mins by mobility shift assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosomal protein S6 kinase alpha-3(Homo sapiens (Human))
East China University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50431812(CHEMBL2347053)
Affinity DataIC50:  500nMAssay Description:Inhibition of RSK2 (unknown origin) using AKRRRLSSLRA as substrate after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 3(Homo sapiens (Human))
East China University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50431812(CHEMBL2347053)
Affinity DataIC50:  1.15E+3nMAssay Description:Inhibition of ERK1 (unknown origin) after 10 mins by mobility shift assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosomal protein S6 kinase alpha-3(Homo sapiens (Human))
East China University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50431814(CHEMBL2347075)
Affinity DataIC50:  1.51E+3nMAssay Description:Inhibition of RSK2 (unknown origin) using AKRRRLSSLRA as substrate after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosomal protein S6 kinase alpha-3(Homo sapiens (Human))
East China University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50431810(CHEMBL2347061)
Affinity DataIC50:  1.68E+3nMAssay Description:Inhibition of RSK2 (unknown origin) using AKRRRLSSLRA as substrate after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosomal protein S6 kinase alpha-3(Homo sapiens (Human))
East China University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50431815(CHEMBL2347074)
Affinity DataIC50:  2.02E+3nMAssay Description:Inhibition of RSK2 (unknown origin) using AKRRRLSSLRA as substrate after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosomal protein S6 kinase alpha-3(Homo sapiens (Human))
East China University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50431813(CHEMBL2347085)
Affinity DataIC50:  2.49E+3nMAssay Description:Inhibition of RSK2 (unknown origin) using AKRRRLSSLRA as substrate after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosomal protein S6 kinase alpha-3(Homo sapiens (Human))
East China University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50344214(3-((3-phenyl-1H-pyrazol-4-yl)methylene)indolin-2-o...)
Affinity DataIC50:  2.72E+3nMAssay Description:Inhibition of RSK2 (unknown origin) using AKRRRLSSLRA as substrate after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosomal protein S6 kinase alpha-3(Homo sapiens (Human))
East China University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50431816(CHEMBL2347073)
Affinity DataIC50:  3.47E+3nMAssay Description:Inhibition of RSK2 (unknown origin) using AKRRRLSSLRA as substrate after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
East China University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50431812(CHEMBL2347053)
Affinity DataIC50:  5.03E+3nMAssay Description:Inhibition of JNK2 (unknown origin) after 10 mins by mobility shift assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosomal protein S6 kinase alpha-3(Homo sapiens (Human))
East China University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50431816(CHEMBL2347073)
Affinity DataIC50:  7.76E+3nMAssay Description:Inhibition of RSK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosomal protein S6 kinase alpha-3(Homo sapiens (Human))
East China University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50431811(CHEMBL2347054)
Affinity DataIC50:  8.59E+3nMAssay Description:Inhibition of RSK2 (unknown origin) using AKRRRLSSLRA as substrate after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosomal protein S6 kinase alpha-3(Homo sapiens (Human))
East China University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50431809(CHEMBL2347062)
Affinity DataIC50:  1.70E+4nMAssay Description:Inhibition of RSK2 (unknown origin) using AKRRRLSSLRA as substrate after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed