Compile Data Set for Download or QSAR
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Found 23 Enz. Inhib. hit(s) with all data for entry = 50043250
TargetKallikrein-5 [D153N](Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM32709((5-amino-3-pyridin-3-yl-1,2,4-triazol-1-yl)-(4-met...)
Affinity DataKi:  4.40E+3nMAssay Description:Inhibition of human kallikrein 5 measured after 15 mins at pH 8 by double-reciprocal plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKallikrein-7(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM32709((5-amino-3-pyridin-3-yl-1,2,4-triazol-1-yl)-(4-met...)
Affinity DataIC50:  40nMAssay Description:Inhibition of human kallikrein 7 measured after 15 mins at pH 8 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKallikrein-5 [D153N](Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM51911((4-isopropoxybenzyl)-[3-(2-methoxyphenyl)-3-(4-met...)
Affinity DataIC50:  140nMAssay Description:Inhibition of human kallikrein 5 measured after 15 mins at pH 8 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKallikrein-7(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM33882((5-amino-3-pyridin-3-yl-1,2,4-triazol-1-yl)-(4-chl...)
Affinity DataIC50:  220nMAssay Description:Inhibition of human kallikrein 7 measured after 15 mins at pH 8 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKallikrein-7(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM33437((5-amino-3-phenyl-1,2,4-triazol-1-yl)-(3,4-dimetho...)
Affinity DataIC50:  230nMAssay Description:Inhibition of human kallikrein 7 measured after 15 mins at pH 8 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKallikrein-5 [D153N](Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM32709((5-amino-3-pyridin-3-yl-1,2,4-triazol-1-yl)-(4-met...)
Affinity DataIC50:  270nMAssay Description:Inhibition of human kallikrein 5 measured after 15 mins at pH 8 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSuppressor of tumorigenicity 14 protein(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM51911((4-isopropoxybenzyl)-[3-(2-methoxyphenyl)-3-(4-met...)
Affinity DataIC50:  420nMAssay Description:Inhibition of human matriptase measured after 15 mins at pH 8 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSuppressor of tumorigenicity 14 protein(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM32709((5-amino-3-pyridin-3-yl-1,2,4-triazol-1-yl)-(4-met...)
Affinity DataIC50:  570nMAssay Description:Inhibition of human matriptase measured after 15 mins at pH 8 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKallikrein-7(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM33453((3-Amino-[1,2,4]triazol-4-yl)-(4-methoxy-phenyl)-m...)
Affinity DataIC50:  610nMAssay Description:Inhibition of human kallikrein 7 measured after 15 mins at pH 8 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKallikrein-7(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM51911((4-isopropoxybenzyl)-[3-(2-methoxyphenyl)-3-(4-met...)
Affinity DataIC50:  660nMAssay Description:Inhibition of human kallikrein 7 measured after 15 mins at pH 8 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKallikrein-14(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM51911((4-isopropoxybenzyl)-[3-(2-methoxyphenyl)-3-(4-met...)
Affinity DataIC50:  970nMAssay Description:Inhibition of human kallikrein 14 measured after 15 mins at pH 8 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKallikrein-5 [D153N](Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM33453((3-Amino-[1,2,4]triazol-4-yl)-(4-methoxy-phenyl)-m...)
Affinity DataIC50:  990nMAssay Description:Inhibition of human kallikrein 5 measured after 15 mins at pH 8 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKallikrein-5 [D153N](Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM33882((5-amino-3-pyridin-3-yl-1,2,4-triazol-1-yl)-(4-chl...)
Affinity DataIC50:  1.14E+3nMAssay Description:Inhibition of human kallikrein 5 measured after 15 mins at pH 8 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKallikrein-14(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM32709((5-amino-3-pyridin-3-yl-1,2,4-triazol-1-yl)-(4-met...)
Affinity DataIC50:  1.29E+3nMAssay Description:Inhibition of human kallikrein 14 measured after 15 mins at pH 8 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKallikrein-5 [D153N](Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM33437((5-amino-3-phenyl-1,2,4-triazol-1-yl)-(3,4-dimetho...)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of human kallikrein 5 measured after 15 mins at pH 8 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKallikrein-14(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM33453((3-Amino-[1,2,4]triazol-4-yl)-(4-methoxy-phenyl)-m...)
Affinity DataIC50:  3.43E+3nMAssay Description:Inhibition of human kallikrein 14 measured after 15 mins at pH 8 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKallikrein-7(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50438170(CHEMBL2407437)
Affinity DataIC50:  3.50E+3nMAssay Description:Inhibition of human kallikrein 7 measured after 15 mins at pH 8 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSuppressor of tumorigenicity 14 protein(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM33453((3-Amino-[1,2,4]triazol-4-yl)-(4-methoxy-phenyl)-m...)
Affinity DataIC50: >3.00E+4nMpH: 8.0Assay Description:Inhibition of human matriptase measured after 15 mins at pH 8 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSuppressor of tumorigenicity 14 protein(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM33437((5-amino-3-phenyl-1,2,4-triazol-1-yl)-(3,4-dimetho...)
Affinity DataIC50: >3.00E+4nMpH: 8.0Assay Description:Inhibition of human matriptase measured after 15 mins at pH 8 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSuppressor of tumorigenicity 14 protein(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM33882((5-amino-3-pyridin-3-yl-1,2,4-triazol-1-yl)-(4-chl...)
Affinity DataIC50: >3.00E+4nMpH: 8.0Assay Description:Inhibition of human matriptase measured after 15 mins at pH 8 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKallikrein-14(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM33437((5-amino-3-phenyl-1,2,4-triazol-1-yl)-(3,4-dimetho...)
Affinity DataIC50: >3.00E+4nMpH: 8.0Assay Description:Inhibition of human kallikrein 14 measured after 15 mins at pH 8 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKallikrein-5 [D153N](Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50438170(CHEMBL2407437)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human kallikrein 5 measured after 15 mins at pH 8 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKallikrein-14(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM33882((5-amino-3-pyridin-3-yl-1,2,4-triazol-1-yl)-(4-chl...)
Affinity DataIC50: >3.00E+4nMpH: 8.0Assay Description:Inhibition of human kallikrein 14 measured after 15 mins at pH 8 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed