Compile Data Set for Download or QSAR
maximum 50k data
Found 16 Enz. Inhib. hit(s) with all data for entry = 6012
TargetAndrogen receptor(Homo sapiens (Human))
Georgia Institute Of Technology

LigandPNGBDBM8885((1S,2R,10R,11S,14S,15S)-14-hydroxy-2,15-dimethylte...)
Affinity DataKi:  3.20nM IC50:  4.70nMAssay Description:A series of dilutions of the compounds were prepared with 10% DMSO in HDAC assay buffer, and 5uL of the dilution was added to a 50uL reaction so that...More data for this Ligand-Target Pair
TargetAndrogen receptor(Homo sapiens (Human))
Georgia Institute Of Technology

LigandPNGBDBM104030(Aryl Nilutamide HDACi analog 14e)
Affinity DataKi:  440nM IC50:  650nMAssay Description:A series of dilutions of the compounds were prepared with 10% DMSO in HDAC assay buffer, and 5uL of the dilution was added to a 50uL reaction so that...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Georgia Institute Of Technology

LigandPNGBDBM104029(Aryl Nilutamide HDACi analog 14d)
Affinity DataKi:  460nM IC50:  690nMAssay Description:A series of dilutions of the compounds were prepared with 10% DMSO in HDAC assay buffer, and 5uL of the dilution was added to a 50uL reaction so that...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Georgia Institute Of Technology

LigandPNGBDBM104027(Aryl Nilutamide HDACi analog 14b)
Affinity DataKi:  670nM IC50:  1.00E+3nMAssay Description:A series of dilutions of the compounds were prepared with 10% DMSO in HDAC assay buffer, and 5uL of the dilution was added to a 50uL reaction so that...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Georgia Institute Of Technology

LigandPNGBDBM104026(Aryl Nilutamide HDACi analog 14a)
Affinity DataKi:  720nM IC50:  1.08E+3nMAssay Description:A series of dilutions of the compounds were prepared with 10% DMSO in HDAC assay buffer, and 5uL of the dilution was added to a 50uL reaction so that...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Georgia Institute Of Technology

LigandPNGBDBM104028(Aryl Nilutamide HDACi analog 14c)
Affinity DataKi:  800nM IC50:  1.20E+3nMAssay Description:A series of dilutions of the compounds were prepared with 10% DMSO in HDAC assay buffer, and 5uL of the dilution was added to a 50uL reaction so that...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Georgia Institute Of Technology

LigandPNGBDBM104037(Alkyl Nilutamide HDACi analog 15f)
Affinity DataKi:  960nM IC50:  1.43E+3nMAssay Description:A series of dilutions of the compounds were prepared with 10% DMSO in HDAC assay buffer, and 5uL of the dilution was added to a 50uL reaction so that...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Georgia Institute Of Technology

LigandPNGBDBM104031(Aryl Nilutamide HDACi analog 14f)
Affinity DataKi:  1.06E+3nM IC50:  1.59E+3nMAssay Description:A series of dilutions of the compounds were prepared with 10% DMSO in HDAC assay buffer, and 5uL of the dilution was added to a 50uL reaction so that...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Georgia Institute Of Technology

LigandPNGBDBM50135908(4-(4,4-Dimethyl-2,5-dioxo-imidazolidin-1-yl)-2-tri...)
Affinity DataKi:  1.28E+3nM IC50:  1.91E+3nMAssay Description:A series of dilutions of the compounds were prepared with 10% DMSO in HDAC assay buffer, and 5uL of the dilution was added to a 50uL reaction so that...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Georgia Institute Of Technology

LigandPNGBDBM50425732(ENZALUTAMIDE | US10053433, FC 4.129 | US10806720, ...)
Affinity DataKi:  1.35E+3nM IC50:  2.03E+3nMAssay Description:A series of dilutions of the compounds were prepared with 10% DMSO in HDAC assay buffer, and 5uL of the dilution was added to a 50uL reaction so that...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetAndrogen receptor(Homo sapiens (Human))
Georgia Institute Of Technology

LigandPNGBDBM104036(Alkyl Nilutamide HDACi analog 15e)
Affinity DataKi:  2.37E+3nM IC50:  3.55E+3nMAssay Description:A series of dilutions of the compounds were prepared with 10% DMSO in HDAC assay buffer, and 5uL of the dilution was added to a 50uL reaction so that...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Georgia Institute Of Technology

LigandPNGBDBM18525(Bicalutamide | CHEMBL409 | N-[4-cyano-3-(trifluoro...)
Affinity DataKi:  2.46E+3nM IC50:  3.69E+3nMAssay Description:A series of dilutions of the compounds were prepared with 10% DMSO in HDAC assay buffer, and 5uL of the dilution was added to a 50uL reaction so that...More data for this Ligand-Target Pair
TargetAndrogen receptor(Homo sapiens (Human))
Georgia Institute Of Technology

LigandPNGBDBM104035(Alkyl Nilutamide HDACi analog 15d)
Affinity DataKi:  2.60E+3nM IC50:  3.91E+3nMAssay Description:A series of dilutions of the compounds were prepared with 10% DMSO in HDAC assay buffer, and 5uL of the dilution was added to a 50uL reaction so that...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Georgia Institute Of Technology

LigandPNGBDBM104034(Alkyl Nilutamide HDACi analog 15c)
Affinity DataKi:  2.68E+3nM IC50:  4.02E+3nMAssay Description:A series of dilutions of the compounds were prepared with 10% DMSO in HDAC assay buffer, and 5uL of the dilution was added to a 50uL reaction so that...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Georgia Institute Of Technology

LigandPNGBDBM104032(Alkyl Nilutamide HDACi analog 15a)
Affinity DataKi:  3.96E+3nM IC50:  5.93E+3nMAssay Description:A series of dilutions of the compounds were prepared with 10% DMSO in HDAC assay buffer, and 5uL of the dilution was added to a 50uL reaction so that...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Georgia Institute Of Technology

LigandPNGBDBM104033(Alkyl Nilutamide HDACi analog 15b)
Affinity DataKi:  4.48E+3nM IC50:  6.73E+3nMAssay Description:A series of dilutions of the compounds were prepared with 10% DMSO in HDAC assay buffer, and 5uL of the dilution was added to a 50uL reaction so that...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed