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Found 7 Enz. Inhib. hit(s) with all data for entry = 50043817
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Washington University Saint Louis

Curated by ChEMBL
LigandPNGBDBM50446668(CHEMBL3113568)
Affinity DataIC50:  6.30nMAssay Description:Inhibition of PARP-1 (unknown origin) assessed as NAD+ consumption after 20 mins by fluorometric analysis in presence of activated DNAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Washington University Saint Louis

Curated by ChEMBL
LigandPNGBDBM50446671(CHEMBL3113565)
Affinity DataIC50:  11nMAssay Description:Inhibition of PARP-1 (unknown origin) assessed as NAD+ consumption after 20 mins by fluorometric analysis in presence of activated DNAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Washington University Saint Louis

Curated by ChEMBL
LigandPNGBDBM50446667(CHEMBL3113569)
Affinity DataIC50:  19nMAssay Description:Inhibition of PARP-1 (unknown origin) assessed as NAD+ consumption after 20 mins by fluorometric analysis in presence of activated DNAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Washington University Saint Louis

Curated by ChEMBL
LigandPNGBDBM50446666(CHEMBL3113570)
Affinity DataIC50:  22nMAssay Description:Inhibition of PARP-1 (unknown origin) assessed as NAD+ consumption after 20 mins by fluorometric analysis in presence of activated DNAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Washington University Saint Louis

Curated by ChEMBL
LigandPNGBDBM50446670(CHEMBL3113566)
Affinity DataIC50:  26nMAssay Description:Inhibition of PARP-1 (unknown origin) assessed as NAD+ consumption after 20 mins by fluorometric analysis in presence of activated DNAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Washington University Saint Louis

Curated by ChEMBL
LigandPNGBDBM50446669(CHEMBL3113567)
Affinity DataIC50:  30nMAssay Description:Inhibition of PARP-1 (unknown origin) assessed as NAD+ consumption after 20 mins by fluorometric analysis in presence of activated DNAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Washington University Saint Louis

Curated by ChEMBL
LigandPNGBDBM27497(2-(dimethylamino)-N-(6-oxo-5,6-dihydrophenanthridi...)
Affinity DataIC50:  170nMAssay Description:Inhibition of PARP-1 (unknown origin) assessed as NAD+ consumption after 20 mins by fluorometric analysis in presence of activated DNAMore data for this Ligand-Target Pair