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Found 10 Enz. Inhib. hit(s) with all data for entry = 50044082
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
Cairo University

Curated by ChEMBL
LigandPNGBDBM11639(4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)
Affinity DataIC50:  220nMAssay Description:Inhibition of ovine COX2 using arachidonic acid as substrate assessed as conversion of PGH2 to PGF2alpha after 10 mins by EIAMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
Cairo University

Curated by ChEMBL
LigandPNGBDBM50001212(CHEMBL3236732)
Affinity DataIC50:  390nMAssay Description:Inhibition of ovine COX2 using arachidonic acid as substrate assessed as conversion of PGH2 to PGF2alpha after 10 mins by EIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
Cairo University

Curated by ChEMBL
LigandPNGBDBM50001211(CHEMBL3236731)
Affinity DataIC50:  500nMAssay Description:Inhibition of ovine COX2 using arachidonic acid as substrate assessed as conversion of PGH2 to PGF2alpha after 10 mins by EIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
Cairo University

Curated by ChEMBL
LigandPNGBDBM50001213(CHEMBL3236733)
Affinity DataIC50:  720nMAssay Description:Inhibition of ovine COX2 using arachidonic acid as substrate assessed as conversion of PGH2 to PGF2alpha after 10 mins by EIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
Cairo University

Curated by ChEMBL
LigandPNGBDBM50001222(CHEMBL3236734)
Affinity DataIC50:  840nMAssay Description:Inhibition of ovine COX2 using arachidonic acid as substrate assessed as conversion of PGH2 to PGF2alpha after 10 mins by EIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Cairo University

Curated by ChEMBL
LigandPNGBDBM50001212(CHEMBL3236732)
Affinity DataIC50:  2.86E+3nMAssay Description:Inhibition of ovine COX1 using arachidonic acid as substrate assessed as conversion of PGH2 to PGF2alpha after 10 mins by EIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Cairo University

Curated by ChEMBL
LigandPNGBDBM50001211(CHEMBL3236731)
Affinity DataIC50:  3.15E+3nMAssay Description:Inhibition of ovine COX1 using arachidonic acid as substrate assessed as conversion of PGH2 to PGF2alpha after 10 mins by EIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Cairo University

Curated by ChEMBL
LigandPNGBDBM50001213(CHEMBL3236733)
Affinity DataIC50:  4.02E+3nMAssay Description:Inhibition of ovine COX1 using arachidonic acid as substrate assessed as conversion of PGH2 to PGF2alpha after 10 mins by EIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Cairo University

Curated by ChEMBL
LigandPNGBDBM50001222(CHEMBL3236734)
Affinity DataIC50:  4.46E+3nMAssay Description:Inhibition of ovine COX1 using arachidonic acid as substrate assessed as conversion of PGH2 to PGF2alpha after 10 mins by EIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Cairo University

Curated by ChEMBL
LigandPNGBDBM11639(4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of ovine COX1 using arachidonic acid as substrate assessed as conversion of PGH2 to PGF2alpha after 10 mins by EIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed