Compile Data Set for Download or QSAR
maximum 50k data
Found 4 Enz. Inhib. hit(s) with all data for entry = 50044498
TargetTryptophan 5-hydroxylase 1(Rattus norvegicus)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50019143(CHEMBL511275 | US10683309, Example LP533401)
Affinity DataIC50:  400nMAssay Description:Inhibition of TPH-1-mediated serotonin biosynthesis in rat RBL2H3 cells after 48 hrs by RP-HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptophan 5-hydroxylase 1(Rattus norvegicus)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50019142(CHEMBL3288777)
Affinity DataIC50:  6.22E+3nMAssay Description:Inhibition of TPH-1-mediated serotonin biosynthesis in rat RBL2H3 cells after 48 hrs by RP-HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptophan 5-hydroxylase 2(Rattus norvegicus)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50019142(CHEMBL3288777)
Affinity DataIC50:  4.55E+4nMAssay Description:Inhibition of TPH-2-mediated serotonin biosynthesis in rat PC12 cells after 48 hrs by RP-HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptophan 5-hydroxylase 1(Homo sapiens (Human))
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50019142(CHEMBL3288777)
Affinity DataKd:  6.82E+3nMAssay Description:Binding affinity to TPH-1 (unknown origin) by SPR analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed