Compile Data Set for Download or QSAR
maximum 50k data
Found 27 Enz. Inhib. hit(s) with all data for entry = 50040386
TargetPresenilin-2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50393452(CHEMBL2159511)
Affinity DataIC50:  1nMAssay Description:Inhibition of PS2 gamma-secretase expressed in HEK cells harboring Awe-Lon gene assessed as reduction of amyloid beta-42 productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50393452(CHEMBL2159511)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of PS1 gamma-secretase assessed as reduction of amyloid beta-40 production by membrane based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPresenilin-2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50393453(CHEMBL2159510)
Affinity DataIC50:  2nMAssay Description:Inhibition of PS2 gamma-secretase expressed in HEK cells harboring Awe-Lon gene assessed as reduction of amyloid beta-42 productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPresenilin-2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50393454(CHEMBL2159509)
Affinity DataIC50:  3nMAssay Description:Inhibition of PS2 gamma-secretase expressed in HEK cells harboring Awe-Lon gene assessed as reduction of amyloid beta-42 productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPresenilin-2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50393454(CHEMBL2159509)
Affinity DataIC50:  3nMAssay Description:Inhibition of PS2 gamma-secretase expressed in HEK cells harboring Awe-Lon gene assessed as reduction of amyloid beta-42 productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50393453(CHEMBL2159510)
Affinity DataIC50:  3nMAssay Description:Inhibition of PS1 gamma-secretase assessed as reduction of amyloid beta-40 production by membrane based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50393452(CHEMBL2159511)
Affinity DataIC50:  4nMAssay Description:Inhibition of PS1 gamma-secretase expressed in HEK cells harboring Awe-Lon gene assessed as reduction of amyloid beta-40 productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50393453(CHEMBL2159510)
Affinity DataIC50:  5nMAssay Description:Inhibition of PS1 gamma-secretase expressed in HEK cells harboring Awe-Lon gene assessed as reduction of amyloid beta-40 productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50393454(CHEMBL2159509)
Affinity DataIC50:  6nMAssay Description:Inhibition of PS1 gamma-secretase assessed as reduction of amyloid beta-40 production by membrane based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPresenilin-2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50393457(CHEMBL2159689)
Affinity DataIC50:  6nMAssay Description:Inhibition of PS2 gamma-secretase expressed in HEK cells harboring Awe-Lon gene assessed as reduction of amyloid beta-42 productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50393454(CHEMBL2159509)
Affinity DataIC50:  6nMAssay Description:Inhibition of PS1 gamma-secretase assessed as reduction of amyloid beta-40 production by membrane based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50393457(CHEMBL2159689)
Affinity DataIC50:  8nMAssay Description:Inhibition of PS1 gamma-secretase expressed in HEK cells harboring Awe-Lon gene assessed as reduction of amyloid beta-40 productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPresenilin-2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50393451(CHEMBL2159687)
Affinity DataIC50:  8nMAssay Description:Inhibition of PS2 gamma-secretase expressed in HEK cells harboring Awe-Lon gene assessed as reduction of amyloid beta-42 productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50393454(CHEMBL2159509)
Affinity DataIC50:  8nMAssay Description:Inhibition of PS1 gamma-secretase expressed in HEK cells harboring Awe-Lon gene assessed as reduction of amyloid beta-40 productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50393457(CHEMBL2159689)
Affinity DataIC50:  8nMAssay Description:Inhibition of PS1 gamma-secretase assessed as reduction of amyloid beta-40 production by membrane based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50393454(CHEMBL2159509)
Affinity DataIC50:  8nMAssay Description:Inhibition of PS1 gamma-secretase expressed in HEK cells harboring Awe-Lon gene assessed as reduction of amyloid beta-40 productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPresenilin-2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50393455(CHEMBL2159691)
Affinity DataIC50:  16nMAssay Description:Inhibition of PS2 gamma-secretase expressed in HEK cells harboring Awe-Lon gene assessed as reduction of amyloid beta-42 productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50393451(CHEMBL2159687)
Affinity DataIC50:  18nMAssay Description:Inhibition of PS1 gamma-secretase expressed in HEK cells harboring Awe-Lon gene assessed as reduction of amyloid beta-40 productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPresenilin-2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50393456(CHEMBL2159690)
Affinity DataIC50:  20nMAssay Description:Inhibition of PS2 gamma-secretase expressed in HEK cells harboring Awe-Lon gene assessed as reduction of amyloid beta-42 productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50393451(CHEMBL2159687)
Affinity DataIC50:  20nMAssay Description:Inhibition of PS1 gamma-secretase assessed as reduction of amyloid beta-40 production by membrane based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50393455(CHEMBL2159691)
Affinity DataIC50:  22nMAssay Description:Inhibition of PS1 gamma-secretase assessed as reduction of amyloid beta-40 production by membrane based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50393456(CHEMBL2159690)
Affinity DataIC50:  24nMAssay Description:Inhibition of PS1 gamma-secretase assessed as reduction of amyloid beta-40 production by membrane based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50393455(CHEMBL2159691)
Affinity DataIC50:  37nMAssay Description:Inhibition of PS1 gamma-secretase expressed in HEK cells harboring Awe-Lon gene assessed as reduction of amyloid beta-40 productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50393452(CHEMBL2159511)
Affinity DataIC50:  46nMAssay Description:Inhibition of PS1 gamma-secretase expressed in HEK cells harboring Awe-Lon gene assessed as notch cleavageMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50393456(CHEMBL2159690)
Affinity DataIC50:  48nMAssay Description:Inhibition of PS1 gamma-secretase expressed in HEK cells harboring Awe-Lon gene assessed as reduction of amyloid beta-40 productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50393459(CHEMBL2159688)
Affinity DataIC50:  320nMAssay Description:Inhibition of PS1 gamma-secretase assessed as reduction of amyloid beta-40 production by membrane based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50393458(CHEMBL2159686)
Affinity DataIC50:  377nMAssay Description:Inhibition of PS1 gamma-secretase assessed as reduction of amyloid beta-40 production by membrane based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed