Compile Data Set for Download or QSAR
maximum 50k data
Found 38 Enz. Inhib. hit(s) with all data for entry = 50044759
TargetInterstitial collagenase(Homo sapiens (Human))
Universidad Ceu San Pablo

Curated by ChEMBL
LigandPNGBDBM50028942(CHEMBL1235735)
Affinity DataKi:  23nMAssay Description:Inhibition of MMP1 (unknown origin)More data for this Ligand-Target Pair
TargetMatrilysin(Homo sapiens (Human))
Universidad Ceu San Pablo

Curated by ChEMBL
LigandPNGBDBM50028945(CHEMBL1738911)
Affinity DataKi:  79nMAssay Description:Inhibition of MMP7 (unknown origin)More data for this Ligand-Target Pair
TargetMatrilysin(Homo sapiens (Human))
Universidad Ceu San Pablo

Curated by ChEMBL
LigandPNGBDBM50028944(CHEMBL1738910)
Affinity DataKi:  1.00E+4nMAssay Description:Inhibition of MMP7 (unknown origin)More data for this Ligand-Target Pair
TargetCollagenase 3(Homo sapiens (Human))
Universidad Ceu San Pablo

Curated by ChEMBL
LigandPNGBDBM50265079((4-[1-methyl-2,4-dioxo-6-(3-phenyl-prop-1-ynyl)-1,...)
Affinity DataIC50:  0.670nMAssay Description:Inhibition of MMP13 (unknown origin)More data for this Ligand-Target Pair
Target72 kDa type IV collagenase(Homo sapiens (Human))
Universidad Ceu San Pablo

Curated by ChEMBL
LigandPNGBDBM50028940(CHEMBL3359657)
Affinity DataIC50:  1.70nMAssay Description:Inhibition of MMP2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Universidad Ceu San Pablo

Curated by ChEMBL
LigandPNGBDBM50028941(CHEMBL3359658)
Affinity DataIC50:  3nMAssay Description:Inhibition of MMP2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Universidad Ceu San Pablo

Curated by ChEMBL
LigandPNGBDBM16596(4-N,6-N-bis[(4-fluoro-3-methylphenyl)methyl]pyrimi...)
Affinity DataIC50:  8nMAssay Description:Inhibition of MMP13 (unknown origin)More data for this Ligand-Target Pair
TargetCollagenase 3(Homo sapiens (Human))
Universidad Ceu San Pablo

Curated by ChEMBL
LigandPNGBDBM50234334(BENZYL 6-BENZYL-5,7-DIOXO-6,7-DIHYDRO-5H-[1,3]THIA...)
Affinity DataIC50:  30nMAssay Description:Inhibition of MMP13 (unknown origin)More data for this Ligand-Target Pair
TargetInterstitial collagenase(Homo sapiens (Human))
Universidad Ceu San Pablo

Curated by ChEMBL
LigandPNGBDBM50028943(CHEMBL3359656)
Affinity DataIC50:  40nMAssay Description:Inhibition of MMP1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Universidad Ceu San Pablo

Curated by ChEMBL
LigandPNGBDBM50028940(CHEMBL3359657)
Affinity DataIC50:  44nMAssay Description:Inhibition of MMP9 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Universidad Ceu San Pablo

Curated by ChEMBL
LigandPNGBDBM50028941(CHEMBL3359658)
Affinity DataIC50:  346nMAssay Description:Inhibition of MMP9 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Universidad Ceu San Pablo

Curated by ChEMBL
LigandPNGBDBM50028939(CHEMBL1231240)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of MMP8 (unknown origin)More data for this Ligand-Target Pair
Target72 kDa type IV collagenase(Homo sapiens (Human))
Universidad Ceu San Pablo

Curated by ChEMBL
LigandPNGBDBM27878(13-(carbamoylmethyl)-3-oxo-N-[(3-oxo-3,4-dihydro-2...)
Affinity DataIC50: >2.50E+3nMAssay Description:Inhibition of MMP2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Universidad Ceu San Pablo

Curated by ChEMBL
LigandPNGBDBM27878(13-(carbamoylmethyl)-3-oxo-N-[(3-oxo-3,4-dihydro-2...)
Affinity DataIC50: >2.50E+3nMAssay Description:Inhibition of MMP3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrilysin(Homo sapiens (Human))
Universidad Ceu San Pablo

Curated by ChEMBL
LigandPNGBDBM27878(13-(carbamoylmethyl)-3-oxo-N-[(3-oxo-3,4-dihydro-2...)
Affinity DataIC50: >2.50E+3nMAssay Description:Inhibition of MMP7 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Universidad Ceu San Pablo

Curated by ChEMBL
LigandPNGBDBM27878(13-(carbamoylmethyl)-3-oxo-N-[(3-oxo-3,4-dihydro-2...)
Affinity DataIC50: >2.50E+3nMAssay Description:Inhibition of MMP1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Universidad Ceu San Pablo

Curated by ChEMBL
LigandPNGBDBM27878(13-(carbamoylmethyl)-3-oxo-N-[(3-oxo-3,4-dihydro-2...)
Affinity DataIC50: >2.50E+3nMAssay Description:Inhibition of MMP14 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
Universidad Ceu San Pablo

Curated by ChEMBL
LigandPNGBDBM27878(13-(carbamoylmethyl)-3-oxo-N-[(3-oxo-3,4-dihydro-2...)
Affinity DataIC50: >2.50E+3nMAssay Description:Inhibition of MMP12 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Universidad Ceu San Pablo

Curated by ChEMBL
LigandPNGBDBM27878(13-(carbamoylmethyl)-3-oxo-N-[(3-oxo-3,4-dihydro-2...)
Affinity DataIC50: >2.50E+3nMAssay Description:Inhibition of MMP9 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
Universidad Ceu San Pablo

Curated by ChEMBL
LigandPNGBDBM50234334(BENZYL 6-BENZYL-5,7-DIOXO-6,7-DIHYDRO-5H-[1,3]THIA...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of MMP12 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Universidad Ceu San Pablo

Curated by ChEMBL
LigandPNGBDBM50265079((4-[1-methyl-2,4-dioxo-6-(3-phenyl-prop-1-ynyl)-1,...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of MMP9 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrilysin(Homo sapiens (Human))
Universidad Ceu San Pablo

Curated by ChEMBL
LigandPNGBDBM50234334(BENZYL 6-BENZYL-5,7-DIOXO-6,7-DIHYDRO-5H-[1,3]THIA...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of MMP7 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Universidad Ceu San Pablo

Curated by ChEMBL
LigandPNGBDBM50234334(BENZYL 6-BENZYL-5,7-DIOXO-6,7-DIHYDRO-5H-[1,3]THIA...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of MMP14 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Universidad Ceu San Pablo

Curated by ChEMBL
LigandPNGBDBM50265079((4-[1-methyl-2,4-dioxo-6-(3-phenyl-prop-1-ynyl)-1,...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of MMP14 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrilysin(Homo sapiens (Human))
Universidad Ceu San Pablo

Curated by ChEMBL
LigandPNGBDBM50265079((4-[1-methyl-2,4-dioxo-6-(3-phenyl-prop-1-ynyl)-1,...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of MMP7 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-17(Homo sapiens (Human))
Universidad Ceu San Pablo

Curated by ChEMBL
LigandPNGBDBM50234334(BENZYL 6-BENZYL-5,7-DIOXO-6,7-DIHYDRO-5H-[1,3]THIA...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of MMP17 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-17(Homo sapiens (Human))
Universidad Ceu San Pablo

Curated by ChEMBL
LigandPNGBDBM50265079((4-[1-methyl-2,4-dioxo-6-(3-phenyl-prop-1-ynyl)-1,...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of MMP17 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Universidad Ceu San Pablo

Curated by ChEMBL
LigandPNGBDBM50265079((4-[1-methyl-2,4-dioxo-6-(3-phenyl-prop-1-ynyl)-1,...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of MMP3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Universidad Ceu San Pablo

Curated by ChEMBL
LigandPNGBDBM50234334(BENZYL 6-BENZYL-5,7-DIOXO-6,7-DIHYDRO-5H-[1,3]THIA...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of MMP3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Universidad Ceu San Pablo

Curated by ChEMBL
LigandPNGBDBM50234334(BENZYL 6-BENZYL-5,7-DIOXO-6,7-DIHYDRO-5H-[1,3]THIA...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of MMP1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Universidad Ceu San Pablo

Curated by ChEMBL
LigandPNGBDBM50265079((4-[1-methyl-2,4-dioxo-6-(3-phenyl-prop-1-ynyl)-1,...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of MMP1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Universidad Ceu San Pablo

Curated by ChEMBL
LigandPNGBDBM50234334(BENZYL 6-BENZYL-5,7-DIOXO-6,7-DIHYDRO-5H-[1,3]THIA...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of MMP8 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Universidad Ceu San Pablo

Curated by ChEMBL
LigandPNGBDBM50028939(CHEMBL1231240)
Affinity DataIC50:  3.00E+4nMAssay Description:Inhibition of MMP3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Universidad Ceu San Pablo

Curated by ChEMBL
LigandPNGBDBM50234334(BENZYL 6-BENZYL-5,7-DIOXO-6,7-DIHYDRO-5H-[1,3]THIA...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of MMP2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Universidad Ceu San Pablo

Curated by ChEMBL
LigandPNGBDBM50265079((4-[1-methyl-2,4-dioxo-6-(3-phenyl-prop-1-ynyl)-1,...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of MMP2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Universidad Ceu San Pablo

Curated by ChEMBL
LigandPNGBDBM50234334(BENZYL 6-BENZYL-5,7-DIOXO-6,7-DIHYDRO-5H-[1,3]THIA...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of MMP9 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Universidad Ceu San Pablo

Curated by ChEMBL
LigandPNGBDBM50265079((4-[1-methyl-2,4-dioxo-6-(3-phenyl-prop-1-ynyl)-1,...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of MMP8 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
Universidad Ceu San Pablo

Curated by ChEMBL
LigandPNGBDBM50265079((4-[1-methyl-2,4-dioxo-6-(3-phenyl-prop-1-ynyl)-1,...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of MMP12 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed