Compile Data Set for Download or QSAR
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Found 9 Enz. Inhib. hit(s) with all data for entry = 50045428
TargetHypoxia-inducible factor 1-alpha(Homo sapiens (Human))
Dongguk University-Seoul

Curated by ChEMBL
LigandPNGBDBM50179011(CHEMBL380456 | Moracin P)
Affinity DataIC50:  0.650nMAssay Description:Inhibition of Staphylococcus aureus FabI-mediated trans-2-octenoyl N-acetylcysteamine (t-o-NAC thioester) substrate reduction assessed as decrease in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Dongguk University-Seoul

Curated by ChEMBL
LigandPNGBDBM50251014(CHEMBL465881 | moracin N)
Affinity DataIC50:  924nMAssay Description:Inhibition of mushroom tyrosinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Dongguk University-Seoul

Curated by ChEMBL
LigandPNGBDBM50381284(CHEMBL2018876)
Affinity DataIC50:  2.27E+3nMAssay Description:Inhibition of human aromatase in term placenta microsome assessed as radioactivityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Dongguk University-Seoul

Curated by ChEMBL
LigandPNGBDBM50179011(CHEMBL380456 | Moracin P)
Affinity DataIC50:  2.90E+3nMAssay Description:Inhibition of HIF-1alpha in human Hep3B cells assessed as decrease in VEGF level after 20 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Dongguk University-Seoul

Curated by ChEMBL
LigandPNGBDBM9460(3-(4-aminophenyl)-3-ethyl-piperidine-2,6-dione | 3...)
Affinity DataIC50:  6.40E+3nMAssay Description:Inhibition of HIF-1alpha in human Hep3B cells cotransfected with pGL3-HRE-luciferase plasmid after 24 hrs by dual-luciferase reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetHypoxia-inducible factor 1-alpha(Homo sapiens (Human))
Dongguk University-Seoul

Curated by ChEMBL
LigandPNGBDBM50179011(CHEMBL380456 | Moracin P)
Affinity DataIC50:  1.06E+4nMAssay Description:Inhibition of mushroom tyrosinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Dongguk University-Seoul

Curated by ChEMBL
LigandPNGBDBM50062362(Moracin D)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibition of human aromatase in term placenta microsome assessed as radioactivityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Dongguk University-Seoul

Curated by ChEMBL
LigandPNGBDBM50251014(CHEMBL465881 | moracin N)
Affinity DataIC50:  3.11E+4nMAssay Description:Inhibition of mushroom tyrosinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADPH] FabI [9-251](Staphylococcus aureus)
Dongguk University-Seoul

Curated by ChEMBL
LigandPNGBDBM50381284(CHEMBL2018876)
Affinity DataIC50:  8.38E+4nMAssay Description:Inhibition of mushroom tyrosinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed