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Found 20 Enz. Inhib. hit(s) with all data for entry = 50045046
TargetEukaryotic translation initiation factor 2-alpha kinase 3(Homo sapiens (Human))
Dart Neuroscience

Curated by ChEMBL
LigandPNGBDBM50043288(CHEMBL3355039)
Affinity DataIC50:  0.398nMAssay Description:Inhibition of recombinant GST-tagged PERK (unknown origin) by LanthaScreen assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEukaryotic translation initiation factor 2-alpha kinase 3(Homo sapiens (Human))
Dart Neuroscience

Curated by ChEMBL
LigandPNGBDBM50043290(CHEMBL3355038)
Affinity DataIC50:  0.631nMAssay Description:Inhibition of recombinant GST-tagged PERK (unknown origin) by LanthaScreen assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEukaryotic translation initiation factor 2-alpha kinase 3(Homo sapiens (Human))
Dart Neuroscience

Curated by ChEMBL
LigandPNGBDBM50043027(CHEMBL3355037)
Affinity DataIC50:  0.794nMAssay Description:Inhibition of recombinant GST-tagged PERK (unknown origin) by LanthaScreen assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEukaryotic translation initiation factor 2-alpha kinase 3(Homo sapiens (Human))
Dart Neuroscience

Curated by ChEMBL
LigandPNGBDBM50043157(CHEMBL3355046)
Affinity DataIC50:  1nMAssay Description:Inhibition of recombinant GST-tagged PERK (unknown origin) by LanthaScreen assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEukaryotic translation initiation factor 2-alpha kinase 3(Homo sapiens (Human))
Dart Neuroscience

Curated by ChEMBL
LigandPNGBDBM50043286(CHEMBL3355040)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of recombinant GST-tagged PERK (unknown origin) by LanthaScreen assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEukaryotic translation initiation factor 2-alpha kinase 3(Homo sapiens (Human))
Dart Neuroscience

Curated by ChEMBL
LigandPNGBDBM50043285(CHEMBL3355041)
Affinity DataIC50:  3.20nMAssay Description:Inhibition of recombinant GST-tagged PERK (unknown origin) by LanthaScreen assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEukaryotic translation initiation factor 2-alpha kinase 3(Homo sapiens (Human))
Dart Neuroscience

Curated by ChEMBL
LigandPNGBDBM50043219(CHEMBL3355043)
Affinity DataIC50:  5nMAssay Description:Inhibition of recombinant GST-tagged PERK (unknown origin) by LanthaScreen assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEukaryotic translation initiation factor 2-alpha kinase 3(Homo sapiens (Human))
Dart Neuroscience

Curated by ChEMBL
LigandPNGBDBM50043284(CHEMBL3355042)
Affinity DataIC50:  6.30nMAssay Description:Inhibition of recombinant GST-tagged PERK (unknown origin) by LanthaScreen assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEukaryotic translation initiation factor 2-alpha kinase 3(Homo sapiens (Human))
Dart Neuroscience

Curated by ChEMBL
LigandPNGBDBM50043166(CHEMBL3355045)
Affinity DataIC50:  10nMAssay Description:Inhibition of recombinant GST-tagged PERK (unknown origin) by LanthaScreen assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEukaryotic translation initiation factor 2-alpha kinase 3(Homo sapiens (Human))
Dart Neuroscience

Curated by ChEMBL
LigandPNGBDBM50043157(CHEMBL3355046)
Affinity DataIC50:  13nMAssay Description:Inhibition of PERK (unknown origin) expressed in HEK293 cells assessed as inhibition of phosphorylation of GFP-eIF2 alpha by cell-based TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEukaryotic translation initiation factor 2-alpha kinase 3(Homo sapiens (Human))
Dart Neuroscience

Curated by ChEMBL
LigandPNGBDBM50043027(CHEMBL3355037)
Affinity DataIC50:  20nMAssay Description:Inhibition of PERK (unknown origin) expressed in HEK293 cells assessed as inhibition of phosphorylation of GFP-eIF2 alpha by cell-based TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEukaryotic translation initiation factor 2-alpha kinase 3(Homo sapiens (Human))
Dart Neuroscience

Curated by ChEMBL
LigandPNGBDBM50043290(CHEMBL3355038)
Affinity DataIC50:  25nMAssay Description:Inhibition of PERK (unknown origin) expressed in HEK293 cells assessed as inhibition of phosphorylation of GFP-eIF2 alpha by cell-based TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEukaryotic translation initiation factor 2-alpha kinase 3(Homo sapiens (Human))
Dart Neuroscience

Curated by ChEMBL
LigandPNGBDBM50043286(CHEMBL3355040)
Affinity DataIC50:  40nMAssay Description:Inhibition of PERK (unknown origin) expressed in HEK293 cells assessed as inhibition of phosphorylation of GFP-eIF2 alpha by cell-based TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEukaryotic translation initiation factor 2-alpha kinase 3(Homo sapiens (Human))
Dart Neuroscience

Curated by ChEMBL
LigandPNGBDBM50043288(CHEMBL3355039)
Affinity DataIC50:  50nMAssay Description:Inhibition of PERK (unknown origin) expressed in HEK293 cells assessed as inhibition of phosphorylation of GFP-eIF2 alpha by cell-based TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEukaryotic translation initiation factor 2-alpha kinase 3(Homo sapiens (Human))
Dart Neuroscience

Curated by ChEMBL
LigandPNGBDBM50043285(CHEMBL3355041)
Affinity DataIC50:  79nMAssay Description:Inhibition of PERK (unknown origin) expressed in HEK293 cells assessed as inhibition of phosphorylation of GFP-eIF2 alpha by cell-based TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEukaryotic translation initiation factor 2-alpha kinase 3(Homo sapiens (Human))
Dart Neuroscience

Curated by ChEMBL
LigandPNGBDBM50043218(CHEMBL3355044)
Affinity DataIC50:  251nMAssay Description:Inhibition of recombinant GST-tagged PERK (unknown origin) by LanthaScreen assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEukaryotic translation initiation factor 2-alpha kinase 3(Homo sapiens (Human))
Dart Neuroscience

Curated by ChEMBL
LigandPNGBDBM50043284(CHEMBL3355042)
Affinity DataIC50:  316nMAssay Description:Inhibition of PERK (unknown origin) expressed in HEK293 cells assessed as inhibition of phosphorylation of GFP-eIF2 alpha by cell-based TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEukaryotic translation initiation factor 2-alpha kinase 3(Homo sapiens (Human))
Dart Neuroscience

Curated by ChEMBL
LigandPNGBDBM50043219(CHEMBL3355043)
Affinity DataIC50:  501nMAssay Description:Inhibition of PERK (unknown origin) expressed in HEK293 cells assessed as inhibition of phosphorylation of GFP-eIF2 alpha by cell-based TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEukaryotic translation initiation factor 2-alpha kinase 3(Homo sapiens (Human))
Dart Neuroscience

Curated by ChEMBL
LigandPNGBDBM50043218(CHEMBL3355044)
Affinity DataIC50:  7.94E+3nMAssay Description:Inhibition of PERK (unknown origin) expressed in HEK293 cells assessed as inhibition of phosphorylation of GFP-eIF2 alpha by cell-based TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEukaryotic translation initiation factor 2-alpha kinase 3(Homo sapiens (Human))
Dart Neuroscience

Curated by ChEMBL
LigandPNGBDBM50043166(CHEMBL3355045)
Affinity DataIC50: <3.16E+4nMAssay Description:Inhibition of PERK (unknown origin) expressed in HEK293 cells assessed as inhibition of phosphorylation of GFP-eIF2 alpha by cell-based TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed