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Found 42 Enz. Inhib. hit(s) with all data for entry = 50045838
TargetActivated CDC42 kinase 1(Homo sapiens (Human))
University Of South Florida

Curated by ChEMBL
LigandPNGBDBM50421256(CHEMBL2087874)
Affinity DataKi:  0.300nMAssay Description:Inhibition of ACK1 kinase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
University Of South Florida

Curated by ChEMBL
LigandPNGBDBM50421256(CHEMBL2087874)
Affinity DataKi:  138nMAssay Description:Inhibition of human LCK using peptide poly[Glu:Tyr] (4:1) substrate by 33P Hotspot assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetActivated CDC42 kinase 1(Homo sapiens (Human))
University Of South Florida

Curated by ChEMBL
LigandPNGBDBM50246164(CHEMBL487242 | N3-(2,6-dimethylphenyl)-1-(3-methox...)
Affinity DataIC50:  2nMAssay Description:Inhibition of ACK1 kinase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetActivated CDC42 kinase 1(Homo sapiens (Human))
University Of South Florida

Curated by ChEMBL
LigandPNGBDBM4552(4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-...)
Affinity DataIC50:  2.70nMAssay Description:Inhibition of ACK1 kinase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
University Of South Florida

Curated by ChEMBL
LigandPNGBDBM50084464(CHEMBL3426891)
Affinity DataIC50:  5nMAssay Description:Inhibition of human TYK2 using KKSRGDYMTMQIG peptide substrate by 33P Hotspot assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
University Of South Florida

Curated by ChEMBL
LigandPNGBDBM50204587((S)-6-(4-(2-(dimethylamino)ethoxy)phenyl)-5-phenyl...)
Affinity DataIC50:  6nMAssay Description:Inhibition of human LCK using peptide poly[Glu:Tyr] (4:1) substrate by 33P Hotspot assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
University Of South Florida

Curated by ChEMBL
LigandPNGBDBM50084464(CHEMBL3426891)
Affinity DataIC50:  6nMAssay Description:Inhibition of human JAK2 using poly[Glu:Tyr] (4:1) peptide substrate by 33P Hotspot assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetActivated CDC42 kinase 1(Homo sapiens (Human))
University Of South Florida

Curated by ChEMBL
LigandPNGBDBM50204587((S)-6-(4-(2-(dimethylamino)ethoxy)phenyl)-5-phenyl...)
Affinity DataIC50:  11nMAssay Description:Inhibition of ACK1 kinase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetActivated CDC42 kinase 1(Homo sapiens (Human))
University Of South Florida

Curated by ChEMBL
LigandPNGBDBM50246162(CHEMBL472392 | N3-(2,6-dimethylphenyl)-1-(3-methox...)
Affinity DataIC50:  20nMAssay Description:Inhibition of ACK1 kinase (unknown origin)More data for this Ligand-Target Pair
TargetActivated CDC42 kinase 1(Homo sapiens (Human))
University Of South Florida

Curated by ChEMBL
LigandPNGBDBM50084463(CHEMBL3426880)
Affinity DataIC50:  28nMAssay Description:Inhibition of human ACK1 using EAIYAAPFAKKK peptide substrate by 33P Hotspot assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetActivated CDC42 kinase 1(Homo sapiens (Human))
University Of South Florida

Curated by ChEMBL
LigandPNGBDBM50084454(CHEMBL3426870)
Affinity DataIC50:  33nMAssay Description:Inhibition of human ACK1 using EAIYAAPFAKKK peptide substrate by 33P Hotspot assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetActivated CDC42 kinase 1(Homo sapiens (Human))
University Of South Florida

Curated by ChEMBL
LigandPNGBDBM50084462(CHEMBL3426879)
Affinity DataIC50:  34nMAssay Description:Inhibition of human ACK1 using EAIYAAPFAKKK peptide substrate by 33P Hotspot assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetActivated CDC42 kinase 1(Homo sapiens (Human))
University Of South Florida

Curated by ChEMBL
LigandPNGBDBM98282(US8481733, 94)
Affinity DataIC50:  35nMAssay Description:Inhibition of ACK1 kinase (unknown origin) by cell-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetActivated CDC42 kinase 1(Homo sapiens (Human))
University Of South Florida

Curated by ChEMBL
LigandPNGBDBM50084457(CHEMBL3426873)
Affinity DataIC50:  48nMAssay Description:Inhibition of human ACK1 using EAIYAAPFAKKK peptide substrate by 33P Hotspot assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetActivated CDC42 kinase 1(Homo sapiens (Human))
University Of South Florida

Curated by ChEMBL
LigandPNGBDBM50084456(CHEMBL3426872)
Affinity DataIC50:  48nMAssay Description:Inhibition of human ACK1 using EAIYAAPFAKKK peptide substrate by 33P Hotspot assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetActivated CDC42 kinase 1(Homo sapiens (Human))
University Of South Florida

Curated by ChEMBL
LigandPNGBDBM50084451(CHEMBL3426867)
Affinity DataIC50:  48nMAssay Description:Inhibition of human ACK1 using EAIYAAPFAKKK peptide substrate by 33P Hotspot assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetActivated CDC42 kinase 1(Homo sapiens (Human))
University Of South Florida

Curated by ChEMBL
LigandPNGBDBM50084460(CHEMBL3426876)
Affinity DataIC50:  53nMAssay Description:Inhibition of human ACK1 using EAIYAAPFAKKK peptide substrate by 33P Hotspot assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetActivated CDC42 kinase 1(Homo sapiens (Human))
University Of South Florida

Curated by ChEMBL
LigandPNGBDBM50084447(CHEMBL3426861)
Affinity DataIC50:  54nMAssay Description:Inhibition of human ACK1 using EAIYAAPFAKKK peptide substrate by 33P Hotspot assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetActivated CDC42 kinase 1(Homo sapiens (Human))
University Of South Florida

Curated by ChEMBL
LigandPNGBDBM50084455(CHEMBL3426871)
Affinity DataIC50:  54nMAssay Description:Inhibition of human ACK1 using EAIYAAPFAKKK peptide substrate by 33P Hotspot assayMore data for this Ligand-Target Pair
TargetActivated CDC42 kinase 1(Homo sapiens (Human))
University Of South Florida

Curated by ChEMBL
LigandPNGBDBM50084464(CHEMBL3426891)
Affinity DataIC50:  56nMAssay Description:Inhibition of ACK1 kinase (unknown origin)More data for this Ligand-Target Pair
TargetActivated CDC42 kinase 1(Homo sapiens (Human))
University Of South Florida

Curated by ChEMBL
LigandPNGBDBM50084449(CHEMBL3426865)
Affinity DataIC50:  68nMAssay Description:Inhibition of human ACK1 using EAIYAAPFAKKK peptide substrate by 33P Hotspot assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetActivated CDC42 kinase 1(Homo sapiens (Human))
University Of South Florida

Curated by ChEMBL
LigandPNGBDBM50084452(CHEMBL3426868)
Affinity DataIC50:  81nMAssay Description:Inhibition of human ACK1 using EAIYAAPFAKKK peptide substrate by 33P Hotspot assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetActivated CDC42 kinase 1(Homo sapiens (Human))
University Of South Florida

Curated by ChEMBL
LigandPNGBDBM50084465(CHEMBL3426892)
Affinity DataIC50:  82nMAssay Description:Inhibition of ACK1 kinase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetActivated CDC42 kinase 1(Homo sapiens (Human))
University Of South Florida

Curated by ChEMBL
LigandPNGBDBM50084461(CHEMBL3426877)
Affinity DataIC50:  85nMAssay Description:Inhibition of human ACK1 using EAIYAAPFAKKK peptide substrate by 33P Hotspot assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetActivated CDC42 kinase 1(Homo sapiens (Human))
University Of South Florida

Curated by ChEMBL
LigandPNGBDBM50084453(CHEMBL3426869)
Affinity DataIC50:  95nMAssay Description:Inhibition of human ACK1 using EAIYAAPFAKKK peptide substrate by 33P Hotspot assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetActivated CDC42 kinase 1(Homo sapiens (Human))
University Of South Florida

Curated by ChEMBL
LigandPNGBDBM50084448(CHEMBL3426862)
Affinity DataIC50:  99nMAssay Description:Inhibition of human ACK1 using EAIYAAPFAKKK peptide substrate by 33P Hotspot assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetActivated CDC42 kinase 1(Homo sapiens (Human))
University Of South Florida

Curated by ChEMBL
LigandPNGBDBM50084450(CHEMBL3426866)
Affinity DataIC50:  106nMAssay Description:Inhibition of human ACK1 using EAIYAAPFAKKK peptide substrate by 33P Hotspot assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetActivated CDC42 kinase 1(Homo sapiens (Human))
University Of South Florida

Curated by ChEMBL
LigandPNGBDBM98282(US8481733, 94)
Affinity DataIC50:  110nMAssay Description:Inhibition of ACK1 kinase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
University Of South Florida

Curated by ChEMBL
LigandPNGBDBM50204589((S)-5,6-diphenyl-N-((tetrahydrofuran-2-yl)methyl)f...)
Affinity DataIC50:  122nMAssay Description:Inhibition of human LCK using peptide poly[Glu:Tyr] (4:1) substrate by 33P Hotspot assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase ROS(Homo sapiens (Human))
University Of South Florida

Curated by ChEMBL
LigandPNGBDBM50084464(CHEMBL3426891)
Affinity DataIC50:  124nMAssay Description:Inhibition of human ROS/ROS1 using KKKSPGEYVNIEFG peptide substrate by 33P Hotspot assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
University Of South Florida

Curated by ChEMBL
LigandPNGBDBM50084464(CHEMBL3426891)
Affinity DataIC50:  136nMAssay Description:Inhibition of human LCK using peptide poly[Glu:Tyr] (4:1) substrate by 33P Hotspot assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
University Of South Florida

Curated by ChEMBL
LigandPNGBDBM50084464(CHEMBL3426891)
Affinity DataIC50:  143nMAssay Description:Inhibition of human ALK using poly[Glu:Tyr] (4:1) peptide substrate by 33P Hotspot assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
University Of South Florida

Curated by ChEMBL
LigandPNGBDBM50084464(CHEMBL3426891)
Affinity DataIC50:  154nMAssay Description:Inhibition of human CHK1 using KKKVSRSGLYRSPSMPENLNRPR peptide substrate by 33P Hotspot assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
University Of South Florida

Curated by ChEMBL
LigandPNGBDBM50084464(CHEMBL3426891)
Affinity DataIC50:  160nMAssay Description:Inhibition of human FGFR1 using KKKSPGEYVNIEFG peptide substrate by 33P Hotspot assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetActivated CDC42 kinase 1(Homo sapiens (Human))
University Of South Florida

Curated by ChEMBL
LigandPNGBDBM50084446(CHEMBL3426860)
Affinity DataIC50:  164nMAssay Description:Inhibition of human ACK1 using EAIYAAPFAKKK peptide substrate by 33P Hotspot assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetActivated CDC42 kinase 1(Homo sapiens (Human))
University Of South Florida

Curated by ChEMBL
LigandPNGBDBM50084459(CHEMBL3426875)
Affinity DataIC50:  169nMAssay Description:Inhibition of human ACK1 using EAIYAAPFAKKK peptide substrate by 33P Hotspot assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
University Of South Florida

Curated by ChEMBL
LigandPNGBDBM50084464(CHEMBL3426891)
Affinity DataIC50:  206nMAssay Description:Inhibition of human ABL1 using EAIYAAPFAKKK peptide substrate by 33P Hotspot assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetActivated CDC42 kinase 1(Homo sapiens (Human))
University Of South Florida

Curated by ChEMBL
LigandPNGBDBM50084458(CHEMBL3426874)
Affinity DataIC50:  231nMAssay Description:Inhibition of human ACK1 using EAIYAAPFAKKK peptide substrate by 33P Hotspot assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetActivated CDC42 kinase 1(Homo sapiens (Human))
University Of South Florida

Curated by ChEMBL
LigandPNGBDBM50084444(CHEMBL3426857)
Affinity DataIC50:  299nMAssay Description:Inhibition of human ACK1 using EAIYAAPFAKKK peptide substrate by 33P Hotspot assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
University Of South Florida

Curated by ChEMBL
LigandPNGBDBM50084464(CHEMBL3426891)
Affinity DataIC50:  438nMAssay Description:Inhibition of human c-Src using poly[Glu:Tyr] (4:1) peptide substrate by 33P Hotspot assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetActivated CDC42 kinase 1(Homo sapiens (Human))
University Of South Florida

Curated by ChEMBL
LigandPNGBDBM50337126(2-(2-methoxy-4-(4-methylpiperazin-1-yl)phenylamino...)
Affinity DataKd:  2nMAssay Description:Inhibition of ACK1 kinase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetActivated CDC42 kinase 1(Homo sapiens (Human))
University Of South Florida

Curated by ChEMBL
LigandPNGBDBM13216(BMS-354825 | CHEMBL1421 | DASATINIB | N-(2-Chloro-...)
Affinity DataKd:  6nMAssay Description:Inhibition of ACK1 kinase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed