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Found 62 Enz. Inhib. hit(s) with all data for entry = 50045533
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50066870(CHEMBL3401672)
Affinity DataIC50:  0.900nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells using NADPH assessed as conversion of cortisone to cortisol by cell-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50066894(CHEMBL3401683)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells using NADPH assessed as conversion of cortisone to cortisol by cell-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50066871(CHEMBL3401671)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells using NADPH assessed as conversion of cortisone to cortisol by cell-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50066892(CHEMBL3401681)
Affinity DataIC50:  1.80nMAssay Description:Inhibition of human 11beta-HSD1 using microsomal fraction and NADPH assessed as conversion of cortisone to cortisol by biochemical enzyme assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50066887(CHEMBL3401676)
Affinity DataIC50:  1.80nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells using NADPH assessed as conversion of cortisone to cortisol by cell-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50066874(CHEMBL3401668)
Affinity DataIC50:  2nMAssay Description:Inhibition of human 11beta-HSD2 using microsomal fraction and NADPH assessed as conversion of cortisone to cortisol by biochemical enzyme assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50066873(CHEMBL3401669)
Affinity DataIC50:  2.10nMAssay Description:Inhibition of human 11beta-HSD2 using microsomal fraction and NADPH assessed as conversion of cortisone to cortisol by biochemical enzyme assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50066880(CHEMBL3401662)
Affinity DataIC50:  2.20nMAssay Description:Inhibition of human 11beta-HSD1 using microsomal fraction and NADPH assessed as conversion of cortisone to cortisol by biochemical enzyme assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50066892(CHEMBL3401681)
Affinity DataIC50:  2.20nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells using NADPH assessed as conversion of cortisone to cortisol by cell-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50066885(CHEMBL3401674)
Affinity DataIC50:  2.30nMAssay Description:Inhibition of mouse 11beta-HSD1 using microsomal fraction and NADPH assessed as conversion of cortisone to cortisol by biochemical enzyme assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50066883(CHEMBL3401659)
Affinity DataIC50:  2.40nMAssay Description:Inhibition of human 11beta-HSD1 using microsomal fraction and NADPH assessed as conversion of cortisone to cortisol by biochemical enzyme assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50066871(CHEMBL3401671)
Affinity DataIC50:  2.5nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells using NADPH assessed as conversion of cortisone to cortisol by cell-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50066890(CHEMBL3401679)
Affinity DataIC50:  2.70nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells using NADPH assessed as conversion of cortisone to cortisol by cell-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50060409(CHEMBL3394415)
Affinity DataIC50:  2.80nMAssay Description:Inhibition of human 11beta-HSD1 using microsomal fraction and NADPH assessed as conversion of cortisone to cortisol by biochemical enzyme assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50066877(CHEMBL3401665)
Affinity DataIC50:  3.10nMAssay Description:Inhibition of human 11beta-HSD1 using microsomal fraction and NADPH assessed as conversion of cortisone to cortisol by biochemical enzyme assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50066892(CHEMBL3401681)
Affinity DataIC50:  3.10nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells using NADPH assessed as conversion of cortisone to cortisol by cell-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50066876(CHEMBL3401666)
Affinity DataIC50:  3.40nMAssay Description:Inhibition of human 11beta-HSD1 using microsomal fraction and NADPH assessed as conversion of cortisone to cortisol by biochemical enzyme assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50066888(CHEMBL3401677)
Affinity DataIC50:  3.5nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells using NADPH assessed as conversion of cortisone to cortisol by cell-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50066881(CHEMBL3401661)
Affinity DataIC50:  3.5nMAssay Description:Inhibition of human 11beta-HSD1 using microsomal fraction and NADPH assessed as conversion of cortisone to cortisol by biochemical enzyme assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50066875(CHEMBL3401667)
Affinity DataIC50:  3.60nMAssay Description:Inhibition of mouse 11beta-HSD1 using microsomal fraction and NADPH assessed as conversion of cortisone to cortisol by biochemical enzyme assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50066879(CHEMBL3401663)
Affinity DataIC50:  3.80nMAssay Description:Inhibition of human 11beta-HSD1 using microsomal fraction and NADPH assessed as conversion of cortisone to cortisol by biochemical enzyme assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50066895(CHEMBL3401684)
Affinity DataIC50:  3.80nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells using NADPH assessed as conversion of cortisone to cortisol by cell-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50066871(CHEMBL3401671)
Affinity DataIC50:  3.90nMAssay Description:Inhibition of human 11beta-HSD1 using microsomal fraction and NADPH assessed as conversion of cortisone to cortisol by biochemical enzyme assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50066896(CHEMBL3401685)
Affinity DataIC50:  4.10nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells using NADPH assessed as conversion of cortisone to cortisol by cell-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50066893(CHEMBL3401682)
Affinity DataIC50:  4.20nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells using NADPH assessed as conversion of cortisone to cortisol by cell-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50066878(CHEMBL3401664)
Affinity DataIC50:  4.20nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells using NADPH assessed as conversion of cortisone to cortisol by cell-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50066886(CHEMBL3401675)
Affinity DataIC50:  4.30nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells using NADPH assessed as conversion of cortisone to cortisol by cell-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50066896(CHEMBL3401685)
Affinity DataIC50:  4.90nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells using NADPH assessed as conversion of cortisone to cortisol by cell-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50066891(CHEMBL3401680)
Affinity DataIC50:  5.30nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells using NADPH assessed as conversion of cortisone to cortisol by cell-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50066888(CHEMBL3401677)
Affinity DataIC50:  5.40nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells using NADPH assessed as conversion of cortisone to cortisol by cell-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50066884(CHEMBL3401673)
Affinity DataIC50:  5.5nMAssay Description:Inhibition of mouse 11beta-HSD1 using microsomal fraction and NADPH assessed as conversion of cortisone to cortisol by biochemical enzyme assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50066890(CHEMBL3401679)
Affinity DataIC50:  6nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells using NADPH assessed as conversion of cortisone to cortisol by cell-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50066889(CHEMBL3401678)
Affinity DataIC50:  6.60nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells using NADPH assessed as conversion of cortisone to cortisol by cell-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50066896(CHEMBL3401685)
Affinity DataIC50:  6.60nMAssay Description:Inhibition of human 11beta-HSD1 using microsomal fraction and NADPH assessed as conversion of cortisone to cortisol by biochemical enzyme assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50060409(CHEMBL3394415)
Affinity DataIC50:  6.70nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells using NADPH assessed as conversion of cortisone to cortisol by cell-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50066882(CHEMBL3401660)
Affinity DataIC50:  6.80nMAssay Description:Inhibition of human 11beta-HSD1 using microsomal fraction and NADPH assessed as conversion of cortisone to cortisol by biochemical enzyme assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50066893(CHEMBL3401682)
Affinity DataIC50:  6.80nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells using NADPH assessed as conversion of cortisone to cortisol by cell-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50066887(CHEMBL3401676)
Affinity DataIC50:  7.80nMAssay Description:Inhibition of human 11beta-HSD1 using microsomal fraction and NADPH assessed as conversion of cortisone to cortisol by biochemical enzyme assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50066894(CHEMBL3401683)
Affinity DataIC50:  8.20nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells using NADPH assessed as conversion of cortisone to cortisol by cell-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50066872(CHEMBL3401670)
Affinity DataIC50:  8.70nMAssay Description:Inhibition of human 11beta-HSD2 using microsomal fraction and NADPH assessed as conversion of cortisone to cortisol by biochemical enzyme assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50066895(CHEMBL3401684)
Affinity DataIC50:  9.20nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells using NADPH assessed as conversion of cortisone to cortisol by cell-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50066877(CHEMBL3401665)
Affinity DataIC50:  9.5nMAssay Description:Inhibition of human 11beta-HSD1 using microsomal fraction and NADPH assessed as conversion of cortisone to cortisol by biochemical enzyme assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50066889(CHEMBL3401678)
Affinity DataIC50:  9.80nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells using NADPH assessed as conversion of cortisone to cortisol by cell-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50066873(CHEMBL3401669)
Affinity DataIC50:  11nMAssay Description:Inhibition of human 11beta-HSD1 using microsomal fraction and NADPH assessed as conversion of cortisone to cortisol by biochemical enzyme assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50066880(CHEMBL3401662)
Affinity DataIC50:  11nMAssay Description:Inhibition of human 11beta-HSD1 using microsomal fraction and NADPH assessed as conversion of cortisone to cortisol by biochemical enzyme assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50066885(CHEMBL3401674)
Affinity DataIC50:  12nMAssay Description:Inhibition of human 11beta-HSD1 using microsomal fraction and NADPH assessed as conversion of cortisone to cortisol by biochemical enzyme assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50066883(CHEMBL3401659)
Affinity DataIC50:  12nMAssay Description:Inhibition of human 11beta-HSD1 using microsomal fraction and NADPH assessed as conversion of cortisone to cortisol by biochemical enzyme assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50066886(CHEMBL3401675)
Affinity DataIC50:  13nMAssay Description:Inhibition of human 11beta-HSD1 using microsomal fraction and NADPH assessed as conversion of cortisone to cortisol by biochemical enzyme assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50066891(CHEMBL3401680)
Affinity DataIC50:  14nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells using NADPH assessed as conversion of cortisone to cortisol by cell-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50066874(CHEMBL3401668)
Affinity DataIC50:  15nMAssay Description:Inhibition of human 11beta-HSD1 using microsomal fraction and NADPH assessed as conversion of cortisone to cortisol by biochemical enzyme assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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