Found 121 Enz. Inhib. hit(s) with all data for entry = 50045764 
Affinity DataIC50: 2nMAssay Description:Inhibition of human F10a using S-2765 as substrate after 45 mins by spectra max analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 2.20nMAssay Description:Inhibition of human F10a using S-2765 as substrate after 45 mins by spectra max analysisMore data for this Ligand-Target Pair
3D Structure (crystal)
Affinity DataIC50: 3.30nMAssay Description:Inhibition of human F10a using S-2765 as substrate after 45 mins by spectra max analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 6.60nMAssay Description:Inhibition of human F10a using S-2765 as substrate after 45 mins by spectra max analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 7.20nMAssay Description:Inhibition of human F10a using S-2765 as substrate after 45 mins by spectra max analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 9.5nMAssay Description:Inhibition of human F10a using S-2765 as substrate after 45 mins by spectra max analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 150nMAssay Description:Inhibition of F10a in human plasma assessed as doubling of prothombin timeMore data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:Inhibition of F10a in human plasma assessed as doubling of activated partial thromboplastin timeMore data for this Ligand-Target Pair
Affinity DataIC50: 350nMAssay Description:Inhibition of F10a in human plasma assessed as doubling of prothombin timeMore data for this Ligand-Target Pair
Affinity DataIC50: 400nMAssay Description:Inhibition of F10a in human plasma assessed as doubling of prothombin timeMore data for this Ligand-Target Pair
TargetCoagulation factor X(Oryctolagus cuniculus)
Shenyang Pharmaceutical University
Curated by ChEMBL
Shenyang Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 460nMAssay Description:Inhibition of F10a in rabbit plasma assessed as doubling of prothombin timeMore data for this Ligand-Target Pair
TargetCoagulation factor X(Oryctolagus cuniculus)
Shenyang Pharmaceutical University
Curated by ChEMBL
Shenyang Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 510nMAssay Description:Inhibition of F10a in rabbit plasma assessed as doubling of prothombin timeMore data for this Ligand-Target Pair
Affinity DataIC50: 510nMAssay Description:Inhibition of F10a in human plasma assessed as doubling of prothombin timeMore data for this Ligand-Target Pair
Affinity DataIC50: 610nMAssay Description:Inhibition of F10a in human plasma assessed as doubling of prothombin timeMore data for this Ligand-Target Pair
Affinity DataIC50: 650nMAssay Description:Inhibition of F10a in human plasma assessed as doubling of activated partial thromboplastin timeMore data for this Ligand-Target Pair
Affinity DataIC50: 650nMAssay Description:Inhibition of F10a in human plasma assessed as doubling of prothombin timeMore data for this Ligand-Target Pair
Affinity DataIC50: 650nMAssay Description:Inhibition of F10a in human plasma assessed as doubling of prothombin timeMore data for this Ligand-Target Pair
Affinity DataIC50: 700nMAssay Description:Inhibition of F10a in human plasma assessed as doubling of activated partial thromboplastin timeMore data for this Ligand-Target Pair
Affinity DataIC50: 700nMAssay Description:Inhibition of F10a in human plasma assessed as doubling of prothombin timeMore data for this Ligand-Target Pair
TargetCoagulation factor X(Oryctolagus cuniculus)
Shenyang Pharmaceutical University
Curated by ChEMBL
Shenyang Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 720nMAssay Description:Inhibition of F10a in rabbit plasma assessed as doubling of prothombin timeMore data for this Ligand-Target Pair
TargetCoagulation factor X(Oryctolagus cuniculus)
Shenyang Pharmaceutical University
Curated by ChEMBL
Shenyang Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 750nMAssay Description:Inhibition of F10a in rabbit plasma assessed as doubling of activated partial thromboplastin timeMore data for this Ligand-Target Pair
TargetCoagulation factor X(Oryctolagus cuniculus)
Shenyang Pharmaceutical University
Curated by ChEMBL
Shenyang Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 780nMAssay Description:Inhibition of F10a in rabbit plasma assessed as doubling of prothombin timeMore data for this Ligand-Target Pair
Affinity DataIC50: 790nMAssay Description:Inhibition of F10a in human plasma assessed as doubling of activated partial thromboplastin timeMore data for this Ligand-Target Pair
TargetCoagulation factor X(Oryctolagus cuniculus)
Shenyang Pharmaceutical University
Curated by ChEMBL
Shenyang Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 810nMAssay Description:Inhibition of F10a in rabbit plasma assessed as doubling of prothombin timeMore data for this Ligand-Target Pair
TargetCoagulation factor X(Oryctolagus cuniculus)
Shenyang Pharmaceutical University
Curated by ChEMBL
Shenyang Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 820nMAssay Description:Inhibition of F10a in rabbit plasma assessed as doubling of prothombin timeMore data for this Ligand-Target Pair
Affinity DataIC50: 820nMAssay Description:Inhibition of F10a in human plasma assessed as doubling of activated partial thromboplastin timeMore data for this Ligand-Target Pair
TargetCoagulation factor X(Oryctolagus cuniculus)
Shenyang Pharmaceutical University
Curated by ChEMBL
Shenyang Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 860nMAssay Description:Inhibition of F10a in rabbit plasma assessed as doubling of activated partial thromboplastin timeMore data for this Ligand-Target Pair
Affinity DataIC50: 870nMAssay Description:Inhibition of F10a in human plasma assessed as doubling of prothombin timeMore data for this Ligand-Target Pair
TargetCoagulation factor X(Oryctolagus cuniculus)
Shenyang Pharmaceutical University
Curated by ChEMBL
Shenyang Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 890nMAssay Description:Inhibition of F10a in rabbit plasma assessed as doubling of prothombin timeMore data for this Ligand-Target Pair
TargetCoagulation factor X(Oryctolagus cuniculus)
Shenyang Pharmaceutical University
Curated by ChEMBL
Shenyang Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 910nMAssay Description:Inhibition of F10a in rabbit plasma assessed as doubling of prothombin timeMore data for this Ligand-Target Pair
TargetCoagulation factor X(Oryctolagus cuniculus)
Shenyang Pharmaceutical University
Curated by ChEMBL
Shenyang Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 920nMAssay Description:Inhibition of F10a in rabbit plasma assessed as doubling of prothombin timeMore data for this Ligand-Target Pair
Affinity DataIC50: 980nMAssay Description:Inhibition of F10a in human plasma assessed as doubling of activated partial thromboplastin timeMore data for this Ligand-Target Pair
TargetCoagulation factor X(Oryctolagus cuniculus)
Shenyang Pharmaceutical University
Curated by ChEMBL
Shenyang Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 1.03E+3nMAssay Description:Inhibition of F10a in rabbit plasma assessed as doubling of activated partial thromboplastin timeMore data for this Ligand-Target Pair
TargetCoagulation factor X(Oryctolagus cuniculus)
Shenyang Pharmaceutical University
Curated by ChEMBL
Shenyang Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 1.13E+3nMAssay Description:Inhibition of F10a in rabbit plasma assessed as doubling of activated partial thromboplastin timeMore data for this Ligand-Target Pair
TargetCoagulation factor X(Oryctolagus cuniculus)
Shenyang Pharmaceutical University
Curated by ChEMBL
Shenyang Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 1.16E+3nMAssay Description:Inhibition of F10a in rabbit plasma assessed as doubling of activated partial thromboplastin timeMore data for this Ligand-Target Pair
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of F10a in human plasma assessed as doubling of activated partial thromboplastin timeMore data for this Ligand-Target Pair
TargetCoagulation factor X(Oryctolagus cuniculus)
Shenyang Pharmaceutical University
Curated by ChEMBL
Shenyang Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 1.24E+3nMAssay Description:Inhibition of F10a in rabbit plasma assessed as doubling of activated partial thromboplastin timeMore data for this Ligand-Target Pair
Affinity DataIC50: 1.31E+3nMAssay Description:Inhibition of F10a in human plasma assessed as doubling of activated partial thromboplastin timeMore data for this Ligand-Target Pair
Affinity DataIC50: 1.33E+3nMAssay Description:Inhibition of F10a in human plasma assessed as doubling of activated partial thromboplastin timeMore data for this Ligand-Target Pair
TargetCoagulation factor X(Oryctolagus cuniculus)
Shenyang Pharmaceutical University
Curated by ChEMBL
Shenyang Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 1.39E+3nMAssay Description:Inhibition of F10a in rabbit plasma assessed as doubling of activated partial thromboplastin timeMore data for this Ligand-Target Pair
Affinity DataIC50: 1.42E+3nMAssay Description:Inhibition of F10a in human plasma assessed as doubling of prothombin timeMore data for this Ligand-Target Pair
Affinity DataIC50: 1.51E+3nMAssay Description:Inhibition of F10a in human plasma assessed as doubling of prothombin timeMore data for this Ligand-Target Pair
TargetCoagulation factor X(Oryctolagus cuniculus)
Shenyang Pharmaceutical University
Curated by ChEMBL
Shenyang Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 1.52E+3nMAssay Description:Inhibition of F10a in rabbit plasma assessed as doubling of activated partial thromboplastin timeMore data for this Ligand-Target Pair
TargetCoagulation factor X(Oryctolagus cuniculus)
Shenyang Pharmaceutical University
Curated by ChEMBL
Shenyang Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 1.58E+3nMAssay Description:Inhibition of F10a in rabbit plasma assessed as doubling of activated partial thromboplastin timeMore data for this Ligand-Target Pair
TargetCoagulation factor X(Oryctolagus cuniculus)
Shenyang Pharmaceutical University
Curated by ChEMBL
Shenyang Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 1.58E+3nMAssay Description:Inhibition of F10a in rabbit plasma assessed as doubling of prothombin timeMore data for this Ligand-Target Pair
Affinity DataIC50: 1.65E+3nMAssay Description:Inhibition of F10a in human plasma assessed as doubling of prothombin timeMore data for this Ligand-Target Pair
TargetCoagulation factor X(Oryctolagus cuniculus)
Shenyang Pharmaceutical University
Curated by ChEMBL
Shenyang Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 1.66E+3nMAssay Description:Inhibition of F10a in rabbit plasma assessed as doubling of prothombin timeMore data for this Ligand-Target Pair
Affinity DataIC50: 1.71E+3nMAssay Description:Inhibition of F10a in human plasma assessed as doubling of activated partial thromboplastin timeMore data for this Ligand-Target Pair
Affinity DataIC50: 1.74E+3nMAssay Description:Inhibition of F10a in human plasma assessed as doubling of activated partial thromboplastin timeMore data for this Ligand-Target Pair
TargetCoagulation factor X(Oryctolagus cuniculus)
Shenyang Pharmaceutical University
Curated by ChEMBL
Shenyang Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 1.78E+3nMAssay Description:Inhibition of F10a in rabbit plasma assessed as doubling of prothombin timeMore data for this Ligand-Target Pair
