Compile Data Set for Download or QSAR
maximum 50k data
Found 136 Enz. Inhib. hit(s) with all data for entry = 50046050
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50092618(CHEMBL3586362)
Affinity DataIC50:  2nMAssay Description:Displacement of [3H]-PGE2 from human EP2 receptor overexpressed in human ECV304 cell membranes by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Mus musculus (Mouse))
Amgen

Curated by ChEMBL
LigandPNGBDBM50092616(CHEMBL3586360)
Affinity DataIC50:  4nMAssay Description:Antagonist activity at mouse EP2 receptor overexpressed in human ECV304 cells assessed as inhibition of prostaglandin E2-induced cAMP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50092616(CHEMBL3586360)
Affinity DataIC50:  8nMAssay Description:Displacement of [3H]-PGE2 from human EP2 receptor overexpressed in human ECV304 cell membranes by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50092615(CHEMBL3586361)
Affinity DataIC50:  8nMAssay Description:Displacement of [3H]-PGE2 from human EP2 receptor overexpressed in human ECV304 cell membranes by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Mus musculus (Mouse))
Amgen

Curated by ChEMBL
LigandPNGBDBM50092616(CHEMBL3586360)
Affinity DataIC50:  10nMAssay Description:Displacement of [3H]-PGE2 from mouse EP2 receptor overexpressed in human ECV304 cell membranes by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50092618(CHEMBL3586362)
Affinity DataIC50:  10nMAssay Description:Antagonist activity at human EP2 receptor overexpressed in human ECV304 cells assessed as inhibition of prostaglandin E2-induced cAMP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Rattus norvegicus)
Amgen

Curated by ChEMBL
LigandPNGBDBM50092616(CHEMBL3586360)
Affinity DataIC50:  10nMAssay Description:Displacement of [3H]-PGE2 from rat EP2 receptor overexpressed in human ECV304 cell membranes by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50092760(CHEMBL3586312)
Affinity DataIC50:  20nMAssay Description:Displacement of [3H]-PGE2 from human EP2 receptor overexpressed in human ECV304 cell membranes by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50092619(CHEMBL3586359)
Affinity DataIC50:  20nMAssay Description:Displacement of [3H]-PGE2 from human EP2 receptor overexpressed in human ECV304 cell membranes by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50092653(CHEMBL3586347)
Affinity DataIC50:  30nMAssay Description:Displacement of [3H]-PGE2 from human EP2 receptor overexpressed in human ECV304 cell membranes by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Rattus norvegicus)
Amgen

Curated by ChEMBL
LigandPNGBDBM50092616(CHEMBL3586360)
Affinity DataIC50:  30nMAssay Description:Antagonist activity at rat EP2 receptor overexpressed in human ECV304 cells assessed as inhibition of prostaglandin E2-induced cAMP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50092654(CHEMBL3586346)
Affinity DataIC50:  40nMAssay Description:Antagonist activity at human EP2 receptor overexpressed in human ECV304 cells assessed as inhibition of prostaglandin E2-induced cAMP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50092616(CHEMBL3586360)
Affinity DataIC50:  50nMAssay Description:Antagonist activity at human EP2 receptor overexpressed in human ECV304 cells assessed as inhibition of prostaglandin E2-induced cAMP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50092653(CHEMBL3586347)
Affinity DataIC50:  60nMAssay Description:Antagonist activity at human EP2 receptor overexpressed in human ECV304 cells assessed as inhibition of prostaglandin E2-induced cAMP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Mus musculus (Mouse))
Amgen

Curated by ChEMBL
LigandPNGBDBM50092617(CHEMBL3586309)
Affinity DataIC50:  60nMAssay Description:Antagonist activity at mouse EP2 receptor overexpressed in human ECV304 cells assessed as inhibition of prostaglandin E2-induced cAMP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50092725(CHEMBL3586340)
Affinity DataIC50:  60nMAssay Description:Displacement of [3H]-PGE2 from human EP2 receptor overexpressed in human ECV304 cell membranes by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50092617(CHEMBL3586309)
Affinity DataIC50:  70nMAssay Description:Displacement of [3H]-PGE2 from human EP2 receptor overexpressed in human ECV304 cell membranes by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50092760(CHEMBL3586312)
Affinity DataIC50:  80nMAssay Description:Antagonist activity at human EP2 receptor overexpressed in human ECV304 cells assessed as inhibition of prostaglandin E2-induced cAMP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50092723(CHEMBL3586342)
Affinity DataIC50:  80nMAssay Description:Displacement of [3H]-PGE2 from human EP2 receptor overexpressed in human ECV304 cell membranes by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50092638(CHEMBL3586353)
Affinity DataIC50:  80nMAssay Description:Displacement of [3H]-PGE2 from human EP2 receptor overexpressed in human ECV304 cell membranes by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50092654(CHEMBL3586346)
Affinity DataIC50:  90nMAssay Description:Displacement of [3H]-PGE2 from human EP2 receptor overexpressed in human ECV304 cell membranes by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50092763(CHEMBL3586322)
Affinity DataIC50:  100nMAssay Description:Displacement of [3H]-PGE2 from human EP2 receptor overexpressed in human ECV304 cell membranes by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50092749(CHEMBL3586324)
Affinity DataIC50:  100nMAssay Description:Displacement of [3H]-PGE2 from human EP2 receptor overexpressed in human ECV304 cell membranes by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Mus musculus (Mouse))
Amgen

Curated by ChEMBL
LigandPNGBDBM50092617(CHEMBL3586309)
Affinity DataIC50:  100nMAssay Description:Displacement of [3H]-PGE2 from mouse EP2 receptor overexpressed in human ECV304 cell membranes by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50092655(CHEMBL3586345)
Affinity DataIC50:  100nMAssay Description:Displacement of [3H]-PGE2 from human EP2 receptor overexpressed in human ECV304 cell membranes by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Rattus norvegicus)
Amgen

Curated by ChEMBL
LigandPNGBDBM50092617(CHEMBL3586309)
Affinity DataIC50:  100nMAssay Description:Displacement of [3H]-PGE2 from rat EP2 receptor overexpressed in human ECV304 cell membranes by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50092758(CHEMBL3586314)
Affinity DataIC50:  100nMAssay Description:Displacement of [3H]-PGE2 from human EP2 receptor overexpressed in human ECV304 cell membranes by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50092619(CHEMBL3586359)
Affinity DataIC50:  200nMAssay Description:Antagonist activity at human EP2 receptor overexpressed in human ECV304 cells assessed as inhibition of prostaglandin E2-induced cAMP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50092655(CHEMBL3586345)
Affinity DataIC50:  200nMAssay Description:Antagonist activity at human EP2 receptor overexpressed in human ECV304 cells assessed as inhibition of prostaglandin E2-induced cAMP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50092757(CHEMBL3586315)
Affinity DataIC50:  200nMAssay Description:Displacement of [3H]-PGE2 from human EP2 receptor overexpressed in human ECV304 cell membranes by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50092759(CHEMBL3586313)
Affinity DataIC50:  200nMAssay Description:Displacement of [3H]-PGE2 from human EP2 receptor overexpressed in human ECV304 cell membranes by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50092761(CHEMBL3586311)
Affinity DataIC50:  200nMAssay Description:Displacement of [3H]-PGE2 from human EP2 receptor overexpressed in human ECV304 cell membranes by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50092639(CHEMBL3586352)
Affinity DataIC50:  200nMAssay Description:Displacement of [3H]-PGE2 from human EP2 receptor overexpressed in human ECV304 cell membranes by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50092615(CHEMBL3586361)
Affinity DataIC50:  200nMAssay Description:Antagonist activity at human EP2 receptor overexpressed in human ECV304 cells assessed as inhibition of prostaglandin E2-induced cAMP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Rattus norvegicus)
Amgen

Curated by ChEMBL
LigandPNGBDBM50092617(CHEMBL3586309)
Affinity DataIC50:  300nMAssay Description:Antagonist activity at rat EP2 receptor overexpressed in human ECV304 cells assessed as inhibition of prostaglandin E2-induced cAMP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50092745(CHEMBL3586328)
Affinity DataIC50:  300nMAssay Description:Displacement of [3H]-PGE2 from human EP2 receptor overexpressed in human ECV304 cell membranes by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50092728(CHEMBL3586337)
Affinity DataIC50:  300nMAssay Description:Displacement of [3H]-PGE2 from human EP2 receptor overexpressed in human ECV304 cell membranes by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50092724(CHEMBL3586341)
Affinity DataIC50:  400nMAssay Description:Displacement of [3H]-PGE2 from human EP2 receptor overexpressed in human ECV304 cell membranes by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50092730(CHEMBL3586335)
Affinity DataIC50:  400nMAssay Description:Displacement of [3H]-PGE2 from human EP2 receptor overexpressed in human ECV304 cell membranes by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50092757(CHEMBL3586315)
Affinity DataIC50:  500nMAssay Description:Antagonist activity at human EP2 receptor overexpressed in human ECV304 cells assessed as inhibition of prostaglandin E2-induced cAMP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50092750(CHEMBL3586321)
Affinity DataIC50:  600nMAssay Description:Displacement of [3H]-PGE2 from human EP2 receptor overexpressed in human ECV304 cell membranes by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50092751(CHEMBL3586320)
Affinity DataIC50:  600nMAssay Description:Displacement of [3H]-PGE2 from human EP2 receptor overexpressed in human ECV304 cell membranes by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50092617(CHEMBL3586309)
Affinity DataIC50:  600nMAssay Description:Antagonist activity at human EP2 receptor overexpressed in human ECV304 cells assessed as inhibition of prostaglandin E2-induced cAMP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50092730(CHEMBL3586335)
Affinity DataIC50:  600nMAssay Description:Antagonist activity at human EP2 receptor overexpressed in human ECV304 cells assessed as inhibition of prostaglandin E2-induced cAMP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50092732(CHEMBL3586333)
Affinity DataIC50:  700nMAssay Description:Displacement of [3H]-PGE2 from human EP2 receptor overexpressed in human ECV304 cell membranes by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50092762(CHEMBL3586310)
Affinity DataIC50:  700nMAssay Description:Displacement of [3H]-PGE2 from human EP2 receptor overexpressed in human ECV304 cell membranes by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50092723(CHEMBL3586342)
Affinity DataIC50:  700nMAssay Description:Antagonist activity at human EP2 receptor overexpressed in human ECV304 cells assessed as inhibition of prostaglandin E2-induced cAMP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50092722(CHEMBL3586343)
Affinity DataIC50:  800nMAssay Description:Displacement of [3H]-PGE2 from human EP2 receptor overexpressed in human ECV304 cell membranes by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50092761(CHEMBL3586311)
Affinity DataIC50:  900nMAssay Description:Antagonist activity at human EP2 receptor overexpressed in human ECV304 cells assessed as inhibition of prostaglandin E2-induced cAMP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50092725(CHEMBL3586340)
Affinity DataIC50:  900nMAssay Description:Antagonist activity at human EP2 receptor overexpressed in human ECV304 cells assessed as inhibition of prostaglandin E2-induced cAMP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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