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Found 39 Enz. Inhib. hit(s) with all data for entry = 50046712
TargetAcetylcholinesterase(Homo sapiens (Human))
1St Affiliated Hospital Of Guangxi Medical University

Curated by ChEMBL
LigandPNGBDBM8960((+/-)-2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimet...)
Affinity DataIC50:  14nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition by Ellman's m...More data for this Ligand-Target Pair
TargetCholinesterase(Homo sapiens (Human))
1St Affiliated Hospital Of Guangxi Medical University

Curated by ChEMBL
LigandPNGBDBM50127334(CHEMBL3628065)
Affinity DataIC50:  80nMAssay Description:Inhibition of human serum BuChE using S-butyrylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition by Ellman's met...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
1St Affiliated Hospital Of Guangxi Medical University

Curated by ChEMBL
LigandPNGBDBM50127381(CHEMBL3628067)
Affinity DataIC50:  110nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition by Ellman's m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
1St Affiliated Hospital Of Guangxi Medical University

Curated by ChEMBL
LigandPNGBDBM50127382(CHEMBL3628183)
Affinity DataIC50:  210nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition by Ellman's m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
1St Affiliated Hospital Of Guangxi Medical University

Curated by ChEMBL
LigandPNGBDBM50127380(CHEMBL3628066)
Affinity DataIC50:  260nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition by Ellman's m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
1St Affiliated Hospital Of Guangxi Medical University

Curated by ChEMBL
LigandPNGBDBM50127274(CHEMBL3628053)
Affinity DataIC50:  280nMAssay Description:Inhibition of human serum BuChE using S-butyrylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition by Ellman's met...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
1St Affiliated Hospital Of Guangxi Medical University

Curated by ChEMBL
LigandPNGBDBM50127275(CHEMBL3628054)
Affinity DataIC50:  340nMAssay Description:Inhibition of human serum BuChE using S-butyrylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition by Ellman's met...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
1St Affiliated Hospital Of Guangxi Medical University

Curated by ChEMBL
LigandPNGBDBM50127393(CHEMBL3628185)
Affinity DataIC50:  440nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition by Ellman's m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
1St Affiliated Hospital Of Guangxi Medical University

Curated by ChEMBL
LigandPNGBDBM50127389(CHEMBL3628184)
Affinity DataIC50:  530nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition by Ellman's m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
1St Affiliated Hospital Of Guangxi Medical University

Curated by ChEMBL
LigandPNGBDBM50127399(CHEMBL3628186)
Affinity DataIC50:  580nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition by Ellman's m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
1St Affiliated Hospital Of Guangxi Medical University

Curated by ChEMBL
LigandPNGBDBM50127399(CHEMBL3628186)
Affinity DataIC50:  650nMAssay Description:Inhibition of human serum BuChE using S-butyrylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition by Ellman's met...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
1St Affiliated Hospital Of Guangxi Medical University

Curated by ChEMBL
LigandPNGBDBM50127382(CHEMBL3628183)
Affinity DataIC50:  710nMAssay Description:Inhibition of human serum BuChE using S-butyrylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition by Ellman's met...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
1St Affiliated Hospital Of Guangxi Medical University

Curated by ChEMBL
LigandPNGBDBM50127393(CHEMBL3628185)
Affinity DataIC50:  720nMAssay Description:Inhibition of human serum BuChE using S-butyrylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition by Ellman's met...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
1St Affiliated Hospital Of Guangxi Medical University

Curated by ChEMBL
LigandPNGBDBM50127389(CHEMBL3628184)
Affinity DataIC50:  860nMAssay Description:Inhibition of human serum BuChE using S-butyrylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition by Ellman's met...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
1St Affiliated Hospital Of Guangxi Medical University

Curated by ChEMBL
LigandPNGBDBM50127381(CHEMBL3628067)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of human serum BuChE using S-butyrylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition by Ellman's met...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
1St Affiliated Hospital Of Guangxi Medical University

Curated by ChEMBL
LigandPNGBDBM50127334(CHEMBL3628065)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition by Ellman's m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
1St Affiliated Hospital Of Guangxi Medical University

Curated by ChEMBL
LigandPNGBDBM50127380(CHEMBL3628066)
Affinity DataIC50:  2.30E+3nMAssay Description:Inhibition of human serum BuChE using S-butyrylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition by Ellman's met...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
1St Affiliated Hospital Of Guangxi Medical University

Curated by ChEMBL
LigandPNGBDBM50127290(CHEMBL3628059)
Affinity DataIC50:  2.70E+3nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition by Ellman's m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
1St Affiliated Hospital Of Guangxi Medical University

Curated by ChEMBL
LigandPNGBDBM50127276(CHEMBL3628055)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibition of human serum BuChE using S-butyrylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition by Ellman's met...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
1St Affiliated Hospital Of Guangxi Medical University

Curated by ChEMBL
LigandPNGBDBM50127277(CHEMBL3628056)
Affinity DataIC50:  3.20E+3nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition by Ellman's m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
1St Affiliated Hospital Of Guangxi Medical University

Curated by ChEMBL
LigandPNGBDBM50127293(CHEMBL3628062)
Affinity DataIC50:  3.30E+3nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition by Ellman's m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
1St Affiliated Hospital Of Guangxi Medical University

Curated by ChEMBL
LigandPNGBDBM50127289(CHEMBL3628058)
Affinity DataIC50:  3.40E+3nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition by Ellman's m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
1St Affiliated Hospital Of Guangxi Medical University

Curated by ChEMBL
LigandPNGBDBM50127294(CHEMBL3628063)
Affinity DataIC50:  3.80E+3nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition by Ellman's m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
1St Affiliated Hospital Of Guangxi Medical University

Curated by ChEMBL
LigandPNGBDBM50127288(CHEMBL3628057)
Affinity DataIC50:  3.90E+3nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition by Ellman's m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
1St Affiliated Hospital Of Guangxi Medical University

Curated by ChEMBL
LigandPNGBDBM50127277(CHEMBL3628056)
Affinity DataIC50:  4.10E+3nMAssay Description:Inhibition of human serum BuChE using S-butyrylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition by Ellman's met...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
1St Affiliated Hospital Of Guangxi Medical University

Curated by ChEMBL
LigandPNGBDBM50127276(CHEMBL3628055)
Affinity DataIC50:  4.20E+3nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition by Ellman's m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
1St Affiliated Hospital Of Guangxi Medical University

Curated by ChEMBL
LigandPNGBDBM50127289(CHEMBL3628058)
Affinity DataIC50:  4.80E+3nMAssay Description:Inhibition of human serum BuChE using S-butyrylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition by Ellman's met...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
1St Affiliated Hospital Of Guangxi Medical University

Curated by ChEMBL
LigandPNGBDBM50127295(CHEMBL3628064)
Affinity DataIC50:  5.10E+3nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition by Ellman's m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
1St Affiliated Hospital Of Guangxi Medical University

Curated by ChEMBL
LigandPNGBDBM50127288(CHEMBL3628057)
Affinity DataIC50:  5.10E+3nMAssay Description:Inhibition of human serum BuChE using S-butyrylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition by Ellman's met...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
1St Affiliated Hospital Of Guangxi Medical University

Curated by ChEMBL
LigandPNGBDBM8960((+/-)-2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimet...)
Affinity DataIC50:  5.60E+3nMAssay Description:Inhibition of human serum BuChE using S-butyrylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition by Ellman's met...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
1St Affiliated Hospital Of Guangxi Medical University

Curated by ChEMBL
LigandPNGBDBM50127291(CHEMBL3628060)
Affinity DataIC50:  5.70E+3nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition by Ellman's m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
1St Affiliated Hospital Of Guangxi Medical University

Curated by ChEMBL
LigandPNGBDBM50127290(CHEMBL3628059)
Affinity DataIC50:  5.80E+3nMAssay Description:Inhibition of human serum BuChE using S-butyrylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition by Ellman's met...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
1St Affiliated Hospital Of Guangxi Medical University

Curated by ChEMBL
LigandPNGBDBM50127293(CHEMBL3628062)
Affinity DataIC50:  6.80E+3nMAssay Description:Inhibition of human serum BuChE using S-butyrylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition by Ellman's met...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
1St Affiliated Hospital Of Guangxi Medical University

Curated by ChEMBL
LigandPNGBDBM50127295(CHEMBL3628064)
Affinity DataIC50:  7.50E+3nMAssay Description:Inhibition of human serum BuChE using S-butyrylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition by Ellman's met...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
1St Affiliated Hospital Of Guangxi Medical University

Curated by ChEMBL
LigandPNGBDBM50127294(CHEMBL3628063)
Affinity DataIC50:  7.90E+3nMAssay Description:Inhibition of human serum BuChE using S-butyrylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition by Ellman's met...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
1St Affiliated Hospital Of Guangxi Medical University

Curated by ChEMBL
LigandPNGBDBM50127291(CHEMBL3628060)
Affinity DataIC50:  8.90E+3nMAssay Description:Inhibition of human serum BuChE using S-butyrylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition by Ellman's met...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
1St Affiliated Hospital Of Guangxi Medical University

Curated by ChEMBL
LigandPNGBDBM50127292(CHEMBL3628061)
Affinity DataIC50:  2.29E+4nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition by Ellman's m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
1St Affiliated Hospital Of Guangxi Medical University

Curated by ChEMBL
LigandPNGBDBM50127275(CHEMBL3628054)
Affinity DataIC50:  2.86E+4nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition by Ellman's m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
1St Affiliated Hospital Of Guangxi Medical University

Curated by ChEMBL
LigandPNGBDBM50127274(CHEMBL3628053)
Affinity DataIC50:  3.05E+4nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition by Ellman's m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed