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Found 29 Enz. Inhib. hit(s) with all data for entry = 50047378
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
Shandong University

Curated by ChEMBL
LigandPNGBDBM8125((3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl N-[(2S...)
Affinity DataKi:  0.00800nMAssay Description:Binding affinity to wild type HIV1 proteaseMore data for this Ligand-Target Pair
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50163737(CHEMBL3799941)
Affinity DataKi:  1.70nMAssay Description:Inhibition of HIV1 protease using Pr SF-2-WTQ7K-Pr as substrate after 24 hrs by LC/MS-MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50163737(CHEMBL3799941)
Affinity DataKi:  1.70nMAssay Description:Inhibition of HIV1 protease after 48 hrs by micro-titer plate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50163750(CHEMBL3797292)
Affinity DataKi:  4nMAssay Description:Inhibition of HIV1 protease after 48 hrs by micro-titer plate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50200943(CHEMBL269769 | cyclopentyl (2S,3S)-3-[4-([4-(5-chl...)
Affinity DataKi:  8nMAssay Description:Inhibition of HIV1 protease after 48 hrs by micro-titer plate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50163752(CHEMBL3799500)
Affinity DataKi:  16nMAssay Description:Binding affinity to wild type HIV1 proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50163737(CHEMBL3799941)
Affinity DataIC50:  6nMAssay Description:Inhibition of HIV1 protease after 48 hrs by micro-titer plate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50163737(CHEMBL3799941)
Affinity DataIC50:  6nMAssay Description:Inhibition of HIV1 protease using Pr SF-2-WTQ7K-Pr as substrate after 24 hrs by LC/MS-MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50163750(CHEMBL3797292)
Affinity DataIC50:  13nMAssay Description:Inhibition of HIV1 protease after 48 hrs by micro-titer plate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50163751(CHEMBL3799799)
Affinity DataIC50:  40nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50155311(CHEMBL3781301)
Affinity DataIC50:  92nMAssay Description:Antagonist activity against CXCR4 in in human MOLT4 cells assessed as inhibition of SDF1alpha -induced Ca2+ mobilization after 30 mins by FACS analys...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50163751(CHEMBL3799799)
Affinity DataIC50:  650nMAssay Description:Inhibition of human recombinant CCR5 encoding an HIV-1-longterminal-repeat-regulated beta-galactosidase reporter gene expressed in human HeLaP4 cells...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50163738(CHEMBL3799917)
Affinity DataIC50:  4.20E+3nMAssay Description:Inhibition of HIV1 protease using Pr SF-2-WTQ7K-Pr as substrate after 24 hrs by LC/MS-MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50163736(CHEMBL3799805)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of HIV1 integrase using DIG/biotin-tagged annealed U5 LTR sequence oligonucleotides as substrate after 2 hrs by 3-processing strand transf...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50163734(CHEMBL3780574)
Affinity DataIC50:  1.40E+4nMAssay Description:Inhibition of HIV1 subtype B proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50163733(CHEMBL3800610)
Affinity DataIC50:  2.70E+4nMAssay Description:Inhibition of HIV1 subtype B proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50163732(CHEMBL3797729)
Affinity DataIC50:  3.90E+4nMAssay Description:Inhibition of HIV1 subtype B proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50163730(CHEMBL3797258)
Affinity DataIC50:  4.00E+4nMAssay Description:Inhibition of HIV1 subtype B proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50163729(CHEMBL3800626)
Affinity DataIC50:  4.80E+4nMAssay Description:Inhibition of HIV1 subtype B proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50163749(CHEMBL3799880)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of HIV1 protease using Pr SF-2-WTQ7K-Pr as substrate after 24 hrs by LC/MS-MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50163741(CHEMBL3799995)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of HIV1 protease using Pr SF-2-WTQ7K-Pr as substrate after 24 hrs by LC/MS-MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50163740(CHEMBL3800582)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of HIV1 protease using Pr SF-2-WTQ7K-Pr as substrate after 24 hrs by LC/MS-MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50163739(CHEMBL3798397)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of HIV1 protease using Pr SF-2-WTQ7K-Pr as substrate after 24 hrs by LC/MS-MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50163742(CHEMBL3797222)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of HIV1 protease using Pr SF-2-WTQ7K-Pr as substrate after 24 hrs by LC/MS-MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50163725(CHEMBL3800276)
Affinity DataIC50:  1.06E+5nMAssay Description:Inhibition of HIV1 subtype B proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50163735(CHEMBL1738817)
Affinity DataIC50:  2.95E+5nMAssay Description:Inhibition of HIV1 integrase using DIG/biotin-tagged annealed U5 LTR sequence oligonucleotides as substrate after 2 hrs by 3-processing strand transf...More data for this Ligand-Target Pair
TargetIntegrase(Human immunodeficiency virus 1)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50163753(CHEMBL1615094)
Affinity DataKd:  2.80E+6nMAssay Description:Binding affinity to HIV integraseMore data for this Ligand-Target Pair
TargetIntegrase(Human immunodeficiency virus 1)
Shandong University

Curated by ChEMBL
LigandPNGBDBM36291(sesamol)
Affinity DataKd:  5.50E+6nMAssay Description:Binding affinity to HIV integraseMore data for this Ligand-Target Pair
TargetIntegrase(Human immunodeficiency virus 1)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50163754(CHEMBL1614842)
Affinity DataKd:  1.70E+5nMAssay Description:Binding affinity to HIV integraseMore data for this Ligand-Target Pair