Compile Data Set for Download or QSAR
maximum 50k data
Found 4 Enz. Inhib. hit(s) with all data for entry = 50046920
TargetDihydrofolate reductase(Homo sapiens (Human))
Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM18050(2-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)a...)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of human DHFR using 45 uM DHF as substrate by spectrophotometryMore data for this Ligand-Target Pair
TargetDihydrofolate reductase(Mycobacterium tuberculosis)
Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM18050(2-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)a...)
Affinity DataIC50:  8.30nMAssay Description:Inhibition of recombinant Mycobacterium tuberculosis DHFR using 45 uM DHF as substrate by spectrophotometryMore data for this Ligand-Target Pair
TargetDihydrofolate reductase(Mycobacterium tuberculosis)
Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50138163(CHEMBL3752202)
Affinity DataIC50:  2.59E+4nMAssay Description:Inhibition of recombinant Mycobacterium tuberculosis DHFR using 45 uM DHF as substrate by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50138163(CHEMBL3752202)
Affinity DataIC50:  4.20E+4nMAssay Description:Inhibition of human DHFR using 45 uM DHF as substrate by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed