Compile Data Set for Download or QSAR
maximum 50k data
Found 32 Enz. Inhib. hit(s) with all data for entry = 50047052
TargetBeta-secretase 1(Homo sapiens (Human))
Alma Mater Studiorum-University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50145903(CHEMBL3763728)
Affinity DataIC50:  40nMAssay Description:Inhibition of human recombinant BACE1 using M-2420 as substrate preincubated for 1 hr followed by substrate addition incubated for 15 mins by FRET as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Alma Mater Studiorum-University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50145908(CHEMBL3763318)
Affinity DataIC50:  140nMAssay Description:Inhibition of human recombinant BACE1 using M-2420 as substrate preincubated for 1 hr followed by substrate addition incubated for 15 mins by FRET as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Alma Mater Studiorum-University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50145900(CHEMBL3765050)
Affinity DataIC50:  390nMAssay Description:Inhibition of human recombinant BACE1 using M-2420 as substrate preincubated for 1 hr followed by substrate addition incubated for 15 mins by FRET as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Alma Mater Studiorum-University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50145902(CHEMBL3764532)
Affinity DataIC50:  400nMAssay Description:Inhibition of human recombinant BACE1 using M-2420 as substrate preincubated for 1 hr followed by substrate addition incubated for 15 mins by FRET as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Alma Mater Studiorum-University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50145906(CHEMBL454662)
Affinity DataIC50:  530nMAssay Description:Inhibition of human recombinant GSK3-beta using prephosphorylated polypeptide as substrate incubated for 30 mins by Glo-type luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Alma Mater Studiorum-University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50145910(CHEMBL3765711)
Affinity DataIC50:  730nMAssay Description:Inhibition of human recombinant BACE1 using M-2420 as substrate preincubated for 1 hr followed by substrate addition incubated for 15 mins by FRET as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Alma Mater Studiorum-University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50145909(CHEMBL3763944)
Affinity DataIC50:  900nMAssay Description:Inhibition of human recombinant GSK3-beta using prephosphorylated polypeptide as substrate incubated for 30 mins by Glo-type luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Alma Mater Studiorum-University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50145909(CHEMBL3763944)
Affinity DataIC50:  970nMAssay Description:Inhibition of human recombinant BACE1 using M-2420 as substrate preincubated for 1 hr followed by substrate addition incubated for 15 mins by FRET as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Alma Mater Studiorum-University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50145912(CHEMBL3765195)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of human recombinant BACE1 using M-2420 as substrate preincubated for 1 hr followed by substrate addition incubated for 15 mins by FRET as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Alma Mater Studiorum-University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50145917(CHEMBL3764465)
Affinity DataIC50:  1.04E+3nMAssay Description:Inhibition of human recombinant BACE1 using M-2420 as substrate preincubated for 1 hr followed by substrate addition incubated for 15 mins by FRET as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Alma Mater Studiorum-University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50145916(CHEMBL3763264)
Affinity DataIC50:  1.08E+3nMAssay Description:Inhibition of human recombinant BACE1 using M-2420 as substrate preincubated for 1 hr followed by substrate addition incubated for 15 mins by FRET as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Alma Mater Studiorum-University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50145906(CHEMBL454662)
Affinity DataIC50:  1.65E+3nMAssay Description:Inhibition of human recombinant BACE1 using M-2420 as substrate preincubated for 1 hr followed by substrate addition incubated for 15 mins by FRET as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Alma Mater Studiorum-University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50145904(CHEMBL3765061)
Affinity DataIC50:  2.01E+3nMAssay Description:Inhibition of human recombinant GSK3-beta using prephosphorylated polypeptide as substrate incubated for 30 mins by Glo-type luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Alma Mater Studiorum-University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50145908(CHEMBL3763318)
Affinity DataIC50:  2.09E+3nMAssay Description:Inhibition of human recombinant GSK3-beta using prephosphorylated polypeptide as substrate incubated for 30 mins by Glo-type luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Alma Mater Studiorum-University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50145905(CHEMBL3763815)
Affinity DataIC50:  2.28E+3nMAssay Description:Inhibition of human recombinant BACE1 using M-2420 as substrate preincubated for 1 hr followed by substrate addition incubated for 15 mins by FRET as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Alma Mater Studiorum-University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50145903(CHEMBL3763728)
Affinity DataIC50:  2.49E+3nMAssay Description:Inhibition of human recombinant GSK3-beta using prephosphorylated polypeptide as substrate incubated for 30 mins by Glo-type luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Alma Mater Studiorum-University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50145907(CHEMBL131770)
Affinity DataIC50:  2.54E+3nMAssay Description:Inhibition of human recombinant BACE1 using M-2420 as substrate preincubated for 1 hr followed by substrate addition incubated for 15 mins by FRET as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Alma Mater Studiorum-University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50145904(CHEMBL3765061)
Affinity DataIC50:  2.69E+3nMAssay Description:Inhibition of human recombinant BACE1 using M-2420 as substrate preincubated for 1 hr followed by substrate addition incubated for 15 mins by FRET as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Alma Mater Studiorum-University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50145905(CHEMBL3763815)
Affinity DataIC50:  2.78E+3nMAssay Description:Inhibition of human recombinant GSK3-beta using prephosphorylated polypeptide as substrate incubated for 30 mins by Glo-type luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Alma Mater Studiorum-University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50059982((1E,6E)-1,7-Bis-(4-methoxy-phenyl)-hepta-1,6-diene...)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of human recombinant BACE1 using M-2420 as substrate preincubated for 1 hr followed by substrate addition incubated for 15 mins by FRET as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Alma Mater Studiorum-University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50145913(CHEMBL3765319)
Affinity DataIC50:  5.56E+3nMAssay Description:Inhibition of human recombinant GSK3-beta using prephosphorylated polypeptide as substrate incubated for 30 mins by Glo-type luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Alma Mater Studiorum-University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50145913(CHEMBL3765319)
Affinity DataIC50:  6.04E+3nMAssay Description:Inhibition of human recombinant BACE1 using M-2420 as substrate preincubated for 1 hr followed by substrate addition incubated for 15 mins by FRET as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Alma Mater Studiorum-University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50145900(CHEMBL3765050)
Affinity DataIC50:  8.30E+3nMAssay Description:Inhibition of human recombinant GSK3-beta using prephosphorylated polypeptide as substrate incubated for 30 mins by Glo-type luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Alma Mater Studiorum-University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50145907(CHEMBL131770)
Affinity DataIC50:  8.39E+3nMAssay Description:Inhibition of human recombinant GSK3-beta using prephosphorylated polypeptide as substrate incubated for 30 mins by Glo-type luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Alma Mater Studiorum-University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50145912(CHEMBL3765195)
Affinity DataIC50:  9.06E+3nMAssay Description:Inhibition of human recombinant GSK3-beta using prephosphorylated polypeptide as substrate incubated for 30 mins by Glo-type luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Alma Mater Studiorum-University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50145902(CHEMBL3764532)
Affinity DataIC50:  9.63E+3nMAssay Description:Inhibition of human recombinant GSK3-beta using prephosphorylated polypeptide as substrate incubated for 30 mins by Glo-type luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Alma Mater Studiorum-University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50145910(CHEMBL3765711)
Affinity DataIC50:  9.66E+3nMAssay Description:Inhibition of human recombinant GSK3-beta using prephosphorylated polypeptide as substrate incubated for 30 mins by Glo-type luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Alma Mater Studiorum-University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50145917(CHEMBL3764465)
Affinity DataIC50:  1.28E+4nMAssay Description:Inhibition of human recombinant GSK3-beta using prephosphorylated polypeptide as substrate incubated for 30 mins by Glo-type luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Alma Mater Studiorum-University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50059982((1E,6E)-1,7-Bis-(4-methoxy-phenyl)-hepta-1,6-diene...)
Affinity DataIC50:  1.53E+4nMAssay Description:Inhibition of human recombinant GSK3-beta using prephosphorylated polypeptide as substrate incubated for 30 mins by Glo-type luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Alma Mater Studiorum-University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50145916(CHEMBL3763264)
Affinity DataIC50:  1.70E+4nMAssay Description:Inhibition of human recombinant GSK3-beta using prephosphorylated polypeptide as substrate incubated for 30 mins by Glo-type luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Alma Mater Studiorum-University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50140172(CHEBI:3962 | CHEMBL140 | Curcumin | US9409845, Tab...)
Affinity DataIC50:  1.80E+4nMAssay Description:Inhibition of human recombinant GSK3-beta using prephosphorylated polypeptide as substrate incubated for 30 mins by Glo-type luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Alma Mater Studiorum-University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50140172(CHEBI:3962 | CHEMBL140 | Curcumin | US9409845, Tab...)
Affinity DataIC50:  3.43E+5nMAssay Description:Inhibition of human recombinant BACE1 using M-2420 as substrate preincubated for 1 hr followed by substrate addition incubated for 15 mins by FRET as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed