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Found 35 Enz. Inhib. hit(s) with all data for entry = 50046867
TargetSolute carrier family 22 member 12(Homo sapiens (Human))
Shanghai Hengrui Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50134635(CHEMBL3746329 | US9637484, 3)
Affinity DataIC50:  34nMAssay Description:Inhibition of human URAT1 expressed in HEK293 cells assessed as [14C]uric acid uptake after 12 mins by scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSolute carrier family 22 member 12(Homo sapiens (Human))
Shanghai Hengrui Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50134637(CHEMBL3746480 | US9637484, 2)
Affinity DataIC50:  61nMAssay Description:Inhibition of human URAT1 expressed in HEK293 cells assessed as [14C]uric acid uptake after 12 mins by scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSolute carrier family 22 member 12(Homo sapiens (Human))
Shanghai Hengrui Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50134675(CHEMBL3747573 | US9637484, 22)
Affinity DataIC50:  115nMAssay Description:Inhibition of human URAT1 expressed in HEK293 cells assessed as [14C]uric acid uptake after 12 mins by scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSolute carrier family 22 member 12(Homo sapiens (Human))
Shanghai Hengrui Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50134634(CHEMBL3745847 | US9637484, 31)
Affinity DataIC50:  130nMAssay Description:Inhibition of human URAT1 expressed in HEK293 cells assessed as [14C]uric acid uptake after 12 mins by scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSolute carrier family 22 member 12(Homo sapiens (Human))
Shanghai Hengrui Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50134670(CHEMBL3745776 | US9637484, 7)
Affinity DataIC50:  159nMAssay Description:Inhibition of human URAT1 expressed in HEK293 cells assessed as [14C]uric acid uptake after 12 mins by scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSolute carrier family 22 member 12(Homo sapiens (Human))
Shanghai Hengrui Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50134644(CHEMBL3746658 | US9637484, 9)
Affinity DataIC50:  198nMAssay Description:Inhibition of human URAT1 expressed in HEK293 cells assessed as [14C]uric acid uptake after 12 mins by scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSolute carrier family 22 member 12(Homo sapiens (Human))
Shanghai Hengrui Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50134645(CHEMBL3746426 | US9637484, 5)
Affinity DataIC50:  207nMAssay Description:Inhibition of human URAT1 expressed in HEK293 cells assessed as [14C]uric acid uptake after 12 mins by scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSolute carrier family 22 member 12(Homo sapiens (Human))
Shanghai Hengrui Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50134677(CHEMBL3747526 | US9637484, 32)
Affinity DataIC50:  324nMAssay Description:Inhibition of human URAT1 expressed in HEK293 cells assessed as [14C]uric acid uptake after 12 mins by scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSolute carrier family 22 member 12(Homo sapiens (Human))
Shanghai Hengrui Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50134672(CHEMBL3747053)
Affinity DataIC50:  333nMAssay Description:Inhibition of human URAT1 expressed in HEK293 cells assessed as [14C]uric acid uptake after 12 mins by scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSolute carrier family 22 member 12(Homo sapiens (Human))
Shanghai Hengrui Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50134638(CHEMBL3746315 | US9637484, 30)
Affinity DataIC50:  343nMAssay Description:Inhibition of human URAT1 expressed in HEK293 cells assessed as [14C]uric acid uptake after 12 mins by scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSolute carrier family 22 member 12(Homo sapiens (Human))
Shanghai Hengrui Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50134659(CHEMBL3746049 | US9637484, 4)
Affinity DataIC50:  343nMAssay Description:Inhibition of human URAT1 expressed in HEK293 cells assessed as [14C]uric acid uptake after 12 mins by scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSolute carrier family 22 member 12(Homo sapiens (Human))
Shanghai Hengrui Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50134633(CHEMBL3747024 | US9637484, 33)
Affinity DataIC50:  352nMAssay Description:Inhibition of human URAT1 expressed in HEK293 cells assessed as [14C]uric acid uptake after 12 mins by scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSolute carrier family 22 member 12(Homo sapiens (Human))
Shanghai Hengrui Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50134674(CHEMBL3747747 | US9637484, 8)
Affinity DataIC50:  359nMAssay Description:Inhibition of human URAT1 expressed in HEK293 cells assessed as [14C]uric acid uptake after 12 mins by scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSolute carrier family 22 member 12(Homo sapiens (Human))
Shanghai Hengrui Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50134662(CHEMBL3747493 | US9637484, 17)
Affinity DataIC50:  399nMAssay Description:Inhibition of human URAT1 expressed in HEK293 cells assessed as [14C]uric acid uptake after 12 mins by scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSolute carrier family 22 member 12(Homo sapiens (Human))
Shanghai Hengrui Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50134665(CHEMBL3747343 | US9637484, 1)
Affinity DataIC50:  448nMAssay Description:Inhibition of human URAT1 expressed in HEK293 cells assessed as [14C]uric acid uptake after 12 mins by scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSolute carrier family 22 member 12(Homo sapiens (Human))
Shanghai Hengrui Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50134639(CHEMBL3746433 | US9637484, 12)
Affinity DataIC50:  558nMAssay Description:Inhibition of human URAT1 expressed in HEK293 cells assessed as [14C]uric acid uptake after 12 mins by scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSolute carrier family 22 member 12(Homo sapiens (Human))
Shanghai Hengrui Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50134636(CHEMBL3747353 | US9637484, 23)
Affinity DataIC50:  659nMAssay Description:Inhibition of human URAT1 expressed in HEK293 cells assessed as [14C]uric acid uptake after 12 mins by scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSolute carrier family 22 member 12(Homo sapiens (Human))
Shanghai Hengrui Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50134646(CHEMBL3746317 | US9637484, 24)
Affinity DataIC50:  680nMAssay Description:Inhibition of human URAT1 expressed in HEK293 cells assessed as [14C]uric acid uptake after 12 mins by scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSolute carrier family 22 member 12(Homo sapiens (Human))
Shanghai Hengrui Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50134676(CHEMBL3747094 | US9637484, 10)
Affinity DataIC50:  926nMAssay Description:Inhibition of human URAT1 expressed in HEK293 cells assessed as [14C]uric acid uptake after 12 mins by scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSolute carrier family 22 member 12(Homo sapiens (Human))
Shanghai Hengrui Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50134671(CHEMBL3745813 | US9637484, 6)
Affinity DataIC50:  1.19E+3nMAssay Description:Inhibition of human URAT1 expressed in HEK293 cells assessed as [14C]uric acid uptake after 12 mins by scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSolute carrier family 22 member 12(Homo sapiens (Human))
Shanghai Hengrui Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50134647(CHEMBL3747215)
Affinity DataIC50:  1.26E+3nMAssay Description:Inhibition of human URAT1 expressed in HEK293 cells assessed as [14C]uric acid uptake after 12 mins by scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSolute carrier family 22 member 12(Homo sapiens (Human))
Shanghai Hengrui Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50134673(CHEMBL3747110)
Affinity DataIC50:  1.75E+3nMAssay Description:Inhibition of human URAT1 expressed in HEK293 cells assessed as [14C]uric acid uptake after 12 mins by scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSolute carrier family 22 member 12(Homo sapiens (Human))
Shanghai Hengrui Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50134661(CHEMBL3746048)
Affinity DataIC50:  1.79E+3nMAssay Description:Inhibition of human URAT1 expressed in HEK293 cells assessed as [14C]uric acid uptake after 12 mins by scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSolute carrier family 22 member 12(Homo sapiens (Human))
Shanghai Hengrui Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50134643(CHEMBL3747172)
Affinity DataIC50:  1.89E+3nMAssay Description:Inhibition of human URAT1 expressed in HEK293 cells assessed as [14C]uric acid uptake after 12 mins by scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSolute carrier family 22 member 12(Homo sapiens (Human))
Shanghai Hengrui Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50134666(CHEMBL3747643)
Affinity DataIC50:  1.93E+3nMAssay Description:Inhibition of human URAT1 expressed in HEK293 cells assessed as [14C]uric acid uptake after 12 mins by scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSolute carrier family 22 member 12(Homo sapiens (Human))
Shanghai Hengrui Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50134658(CHEMBL3746798)
Affinity DataIC50:  2.76E+3nMAssay Description:Inhibition of human URAT1 expressed in HEK293 cells assessed as [14C]uric acid uptake after 12 mins by scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSolute carrier family 22 member 12(Homo sapiens (Human))
Shanghai Hengrui Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50134640(CHEMBL3746178)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human URAT1 expressed in HEK293 cells assessed as [14C]uric acid uptake after 12 mins by scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSolute carrier family 22 member 12(Homo sapiens (Human))
Shanghai Hengrui Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50134641(CHEMBL3746472)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human URAT1 expressed in HEK293 cells assessed as [14C]uric acid uptake after 12 mins by scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSolute carrier family 22 member 12(Homo sapiens (Human))
Shanghai Hengrui Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50134642(CHEMBL3747474)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human URAT1 expressed in HEK293 cells assessed as [14C]uric acid uptake after 12 mins by scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSolute carrier family 22 member 12(Homo sapiens (Human))
Shanghai Hengrui Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50134669(CHEMBL3746459)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human URAT1 expressed in HEK293 cells assessed as [14C]uric acid uptake after 12 mins by scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSolute carrier family 22 member 12(Homo sapiens (Human))
Shanghai Hengrui Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50134668(CHEMBL3745763)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human URAT1 expressed in HEK293 cells assessed as [14C]uric acid uptake after 12 mins by scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSolute carrier family 22 member 12(Homo sapiens (Human))
Shanghai Hengrui Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50134667(CHEMBL3747377)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human URAT1 expressed in HEK293 cells assessed as [14C]uric acid uptake after 12 mins by scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSolute carrier family 22 member 12(Homo sapiens (Human))
Shanghai Hengrui Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50134664(CHEMBL3747689)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human URAT1 expressed in HEK293 cells assessed as [14C]uric acid uptake after 12 mins by scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSolute carrier family 22 member 12(Homo sapiens (Human))
Shanghai Hengrui Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50134660(CHEMBL3746336)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human URAT1 expressed in HEK293 cells assessed as [14C]uric acid uptake after 12 mins by scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSolute carrier family 22 member 12(Homo sapiens (Human))
Shanghai Hengrui Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50134663(CHEMBL3746789)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human URAT1 expressed in HEK293 cells assessed as [14C]uric acid uptake after 12 mins by scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed