Compile Data Set for Download or QSAR
maximum 50k data
Found 39 Enz. Inhib. hit(s) with all data for entry = 1151
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Hoechst-Roussel Pharmaceuticals

LigandPNGBDBM9349((2Z)-but-2-enedioic acid; 9-amino-6-chloro-1,2,3,4...)
Affinity DataIC50:  11.7nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Hoechst-Roussel Pharmaceuticals

LigandPNGBDBM9352(9-Amino-1 ,2,3,4-tetrahydroacridin-1-ol deriv. 1f ...)
Affinity DataIC50:  292nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Hoechst-Roussel Pharmaceuticals

LigandPNGBDBM8961(1,2,3,4-tetrahydro-9-acridinamine | 1,2,3,4-tetrah...)
Affinity DataIC50:  319nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Hoechst-Roussel Pharmaceuticals

LigandPNGBDBM9381(6-chloro-9-{[(4-fluorophenyl)methyl]amino}-1,2,3,4...)
Affinity DataIC50:  823nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Hoechst-Roussel Pharmaceuticals

LigandPNGBDBM9380(9-(benzylamino)-6-chloro-1,2,3,4-tetrahydroacridin...)
Affinity DataIC50:  1.30E+3nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Hoechst-Roussel Pharmaceuticals

LigandPNGBDBM9354(9-(methylamino)-1,2,3,4-tetrahydroacridin-1-ol | 9...)
Affinity DataIC50:  1.76E+3nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Hoechst-Roussel Pharmaceuticals

LigandPNGBDBM9351(9-Amino-1 ,2,3,4-tetrahydroacridin-1-ol deriv. 1e ...)
Affinity DataIC50:  1.77E+3nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Hoechst-Roussel Pharmaceuticals

LigandPNGBDBM9350((2Z)-but-2-enedioic acid; 9-amino-6-methoxy-1,2,3,...)
Affinity DataIC50:  2.00E+3nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Hoechst-Roussel Pharmaceuticals

LigandPNGBDBM9357((2Z)-but-2-enedioic acid; 9-[(2-phenylethyl)amino]...)
Affinity DataIC50:  3.39E+3nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Hoechst-Roussel Pharmaceuticals

LigandPNGBDBM9358(9-Amino-1 ,2,3,4-tetrahydroacridin-1-ol deriv. 1l ...)
Affinity DataIC50:  3.98E+3nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Hoechst-Roussel Pharmaceuticals

LigandPNGBDBM9347((2Z)-but-2-enedioic acid; 9-amino-1,2,3,4-tetrahyd...)
Affinity DataIC50:  4.00E+3nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Hoechst-Roussel Pharmaceuticals

LigandPNGBDBM9372(9-Amino-1 ,2,3,4-tetrahydroacridin-1-ol deriv. 1z ...)
Affinity DataIC50:  5.89E+3nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Hoechst-Roussel Pharmaceuticals

LigandPNGBDBM9353((2Z)-but-2-enedioic acid; 9-amino-1H,2H,3H-cyclope...)
Affinity DataIC50:  5.97E+3nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Hoechst-Roussel Pharmaceuticals

LigandPNGBDBM9356(9-Amino-1 ,2,3,4-tetrahydroacridin-1-ol deriv. 1j ...)
Affinity DataIC50:  7.68E+3nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Hoechst-Roussel Pharmaceuticals

LigandPNGBDBM9382(9-(benzylamino)-6-fluoro-1,2,3,4-tetrahydroacridin...)
Affinity DataIC50:  8.63E+3nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Hoechst-Roussel Pharmaceuticals

LigandPNGBDBM9363(9-Amino-1 ,2,3,4-tetrahydroacridin-1-ol deriv. 1q ...)
Affinity DataIC50:  1.03E+4nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Hoechst-Roussel Pharmaceuticals

LigandPNGBDBM9371(9-Amino-1 ,2,3,4-tetrahydroacridin-1-ol deriv. 1y ...)
Affinity DataIC50:  1.09E+4nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Hoechst-Roussel Pharmaceuticals

LigandPNGBDBM9378((2E)-but-2-enedioic acid; 9-{[(2,3,4,5,6-pentafluo...)
Affinity DataIC50:  1.26E+4nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Hoechst-Roussel Pharmaceuticals

LigandPNGBDBM9367(9-Amino-1 ,2,3,4-tetrahydroacridin-1-ol deriv. 1u ...)
Affinity DataIC50:  1.31E+4nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Hoechst-Roussel Pharmaceuticals

LigandPNGBDBM9364(9-Amino-1 ,2,3,4-tetrahydroacridin-1-ol deriv. 1r ...)
Affinity DataIC50:  1.33E+4nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Hoechst-Roussel Pharmaceuticals

LigandPNGBDBM9375(9-({[2-(trifluoromethyl)phenyl]methyl}amino)-1,2,3...)
Affinity DataIC50:  1.33E+4nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Hoechst-Roussel Pharmaceuticals

LigandPNGBDBM9355(9-(propylamino)-1,2,3,4-tetrahydroacridin-1-ol | 9...)
Affinity DataIC50:  1.33E+4nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Hoechst-Roussel Pharmaceuticals

LigandPNGBDBM9376(9-({[3-(trifluoromethyl)phenyl]methyl}amino)-1,2,3...)
Affinity DataIC50:  1.42E+4nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Hoechst-Roussel Pharmaceuticals

LigandPNGBDBM9379((2E)-but-2-enedioic acid; 9-[(thiophen-2-ylmethyl)...)
Affinity DataIC50:  1.53E+4nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Hoechst-Roussel Pharmaceuticals

LigandPNGBDBM9368(9-Amino-1 ,2,3,4-tetrahydroacridin-1-ol deriv. 1v ...)
Affinity DataIC50:  1.67E+4nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Hoechst-Roussel Pharmaceuticals

LigandPNGBDBM9377(9-({[4-(trifluoromethyl)phenyl]methyl}amino)-1,2,3...)
Affinity DataIC50:  1.81E+4nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Hoechst-Roussel Pharmaceuticals

LigandPNGBDBM9383(6-fluoro-9-({[2-(trifluoromethyl)phenyl]methyl}ami...)
Affinity DataIC50:  2.01E+4nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Hoechst-Roussel Pharmaceuticals

LigandPNGBDBM9374(9-Amino-1 ,2,3,4-tetrahydroacridin-1-ol deriv. 1bb...)
Affinity DataIC50:  2.10E+4nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Hoechst-Roussel Pharmaceuticals

LigandPNGBDBM9370(9-Amino-1 ,2,3,4-tetrahydroacridin-1-ol deriv. 1x ...)
Affinity DataIC50:  2.11E+4nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Hoechst-Roussel Pharmaceuticals

LigandPNGBDBM9373(9-Amino-1 ,2,3,4-tetrahydroacridin-1-ol deriv. 1aa...)
Affinity DataIC50:  2.45E+4nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Hoechst-Roussel Pharmaceuticals

LigandPNGBDBM9348((2Z)-but-2-enedioic acid; 9-amino-7-chloro-1,2,3,4...)
Affinity DataIC50:  2.47E+4nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Hoechst-Roussel Pharmaceuticals

LigandPNGBDBM9365(9-Amino-1 ,2,3,4-tetrahydroacridin-1-ol deriv. 1s ...)
Affinity DataIC50:  2.72E+4nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Hoechst-Roussel Pharmaceuticals

LigandPNGBDBM9362((2Z)-but-2-enedioic acid; 9-(benzylamino)-1,2,3,4-...)
Affinity DataIC50:  3.22E+4nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Hoechst-Roussel Pharmaceuticals

LigandPNGBDBM9369(9-Amino-1 ,2,3,4-tetrahydroacridin-1-ol deriv. 1w ...)
Affinity DataIC50:  3.60E+4nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Hoechst-Roussel Pharmaceuticals

LigandPNGBDBM9366((2Z)-but-2-enedioic acid; 9-{[(2-fluorophenyl)meth...)
Affinity DataIC50:  4.13E+4nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Hoechst-Roussel Pharmaceuticals

LigandPNGBDBM9359(9-Amino-1 ,2,3,4-tetrahydroacridin-1-ol deriv. 1m ...)
Affinity DataIC50:  4.93E+4nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Hoechst-Roussel Pharmaceuticals

LigandPNGBDBM9361((2E)-but-2-enedioic acid; 9-{[4,4-bis(3-fluorophen...)
Affinity DataIC50:  6.30E+4nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Hoechst-Roussel Pharmaceuticals

LigandPNGBDBM9384(9-(benzylamino)-6-(trifluoromethyl)-1,2,3,4-tetrah...)
Affinity DataIC50:  6.82E+4nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Hoechst-Roussel Pharmaceuticals

LigandPNGBDBM9360(9-Amino-1 ,2,3,4-tetrahydroacridin-1-ol deriv. 1n ...)
Affinity DataIC50:  8.78E+4nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed