Compile Data Set for Download or QSAR
maximum 50k data
Found 35 Enz. Inhib. hit(s) with all data for entry = 50047877
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50192823(CHEMBL3906074)
Affinity DataIC50:  3.10nMAssay Description:Antagonist activity at human recombinant TRPV4 expressed in CHO-K1 cells assessed as blockade of hypotonic solution-induced calcium mobilization by F...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50195055(CHEMBL3954949)
Affinity DataIC50:  6.30nMAssay Description:Antagonist activity at human recombinant TRPV4 expressed in CHO-K1 cells assessed as blockade of 1000 nM 4alphaPDD-induced calcium mobilization by FL...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50195058(CHEMBL3979286)
Affinity DataIC50:  9.5nMAssay Description:Antagonist activity at human recombinant TRPV4 expressed in CHO-K1 cells assessed as blockade of 1000 nM 4alphaPDD-induced calcium mobilization by FL...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM65888((2',4'-Dimethyl-[4,5']bithiazolyl-2-yl...)
Affinity DataIC50:  10nMAssay Description:Antagonist activity at human recombinant TRPV4 expressed in CHO-K1 cells assessed as blockade of 1000 nM 4alphaPDD-induced calcium mobilization by FL...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50195059(CHEMBL3932523)
Affinity DataIC50:  11nMAssay Description:Antagonist activity at human recombinant TRPV4 expressed in CHO-K1 cells assessed as blockade of 1000 nM 4alphaPDD-induced calcium mobilization by FL...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50192823(CHEMBL3906074)
Affinity DataIC50:  19nMAssay Description:Antagonist activity at human recombinant TRPV4 expressed in CHO-K1 cells assessed as blockade of 1000 nM 4alphaPDD-induced calcium mobilization by FL...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50195141(CHEMBL3900585)
Affinity DataIC50:  22nMAssay Description:Antagonist activity at human recombinant TRPV4 expressed in CHO-K1 cells assessed as blockade of 1000 nM 4alphaPDD-induced calcium mobilization by FL...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50195142(CHEMBL3925315)
Affinity DataIC50:  23nMAssay Description:Antagonist activity at human recombinant TRPV4 expressed in CHO-K1 cells assessed as blockade of 1000 nM 4alphaPDD-induced calcium mobilization by FL...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50192802(CHEMBL3927993)
Affinity DataIC50:  24nMAssay Description:Antagonist activity at human recombinant TRPV4 expressed in CHO-K1 cells assessed as blockade of 1000 nM 4alphaPDD-induced calcium mobilization by FL...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50195056(CHEMBL3975583)
Affinity DataIC50:  29nMAssay Description:Antagonist activity at human recombinant TRPV4 expressed in CHO-K1 cells assessed as blockade of 1000 nM 4alphaPDD-induced calcium mobilization by FL...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50195092(CHEMBL3977499)
Affinity DataIC50:  31nMAssay Description:Antagonist activity at human recombinant TRPV4 expressed in CHO-K1 cells assessed as blockade of 1000 nM 4alphaPDD-induced calcium mobilization by FL...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50195220(CHEMBL424708)
Affinity DataIC50:  34nMAssay Description:Antagonist activity at human recombinant TRPV4 expressed in CHO-K1 cells assessed as blockade of 1000 nM 4alphaPDD-induced calcium mobilization by FL...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50195061(CHEMBL3944251)
Affinity DataIC50:  35nMAssay Description:Antagonist activity at human recombinant TRPV4 expressed in CHO-K1 cells assessed as blockade of 1000 nM 4alphaPDD-induced calcium mobilization by FL...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50195139(CHEMBL3946266)
Affinity DataIC50:  37nMAssay Description:Antagonist activity at human recombinant TRPV4 expressed in CHO-K1 cells assessed as blockade of 1000 nM 4alphaPDD-induced calcium mobilization by FL...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50194946(CHEMBL3900878)
Affinity DataIC50:  46nMAssay Description:Antagonist activity at human recombinant TRPV4 expressed in CHO-K1 cells assessed as blockade of 1000 nM 4alphaPDD-induced calcium mobilization by FL...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50195137(CHEMBL3971104)
Affinity DataIC50:  50nMAssay Description:Antagonist activity at human recombinant TRPV4 expressed in CHO-K1 cells assessed as blockade of 1000 nM 4alphaPDD-induced calcium mobilization by FL...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50192821(CHEMBL2133556)
Affinity DataIC50:  57nMAssay Description:Antagonist activity at human recombinant TRPV4 expressed in CHO-K1 cells assessed as blockade of 1000 nM 4alphaPDD-induced calcium mobilization by FL...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50194948(CHEMBL3960032)
Affinity DataIC50:  100nMAssay Description:Antagonist activity at human recombinant TRPV4 expressed in CHO-K1 cells assessed as blockade of 1000 nM 4alphaPDD-induced calcium mobilization by FL...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50195057(CHEMBL3950242)
Affinity DataIC50:  200nMAssay Description:Antagonist activity at human recombinant TRPV4 expressed in CHO-K1 cells assessed as blockade of 1000 nM 4alphaPDD-induced calcium mobilization by FL...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50195221(CHEMBL3971734)
Affinity DataIC50:  240nMAssay Description:Antagonist activity at human recombinant TRPV4 expressed in CHO-K1 cells assessed as blockade of 1000 nM 4alphaPDD-induced calcium mobilization by FL...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50194949(CHEMBL3898828)
Affinity DataIC50:  240nMAssay Description:Antagonist activity at human recombinant TRPV4 expressed in CHO-K1 cells assessed as blockade of 1000 nM 4alphaPDD-induced calcium mobilization by FL...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50194947(CHEMBL3970031)
Affinity DataIC50:  290nMAssay Description:Antagonist activity at human recombinant TRPV4 expressed in CHO-K1 cells assessed as blockade of 1000 nM 4alphaPDD-induced calcium mobilization by FL...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50195062(CHEMBL3916322)
Affinity DataIC50:  410nMAssay Description:Antagonist activity at human recombinant TRPV4 expressed in CHO-K1 cells assessed as blockade of 1000 nM 4alphaPDD-induced calcium mobilization by FL...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50195054(CHEMBL1374508)
Affinity DataIC50:  490nMAssay Description:Antagonist activity at human recombinant TRPV4 expressed in CHO-K1 cells assessed as blockade of 1000 nM 4alphaPDD-induced calcium mobilization by FL...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50195053(CHEMBL3983567)
Affinity DataIC50:  620nMAssay Description:Antagonist activity at human recombinant TRPV4 expressed in CHO-K1 cells assessed as blockade of 1000 nM 4alphaPDD-induced calcium mobilization by FL...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50192823(CHEMBL3906074)
Affinity DataIC50:  800nMAssay Description:Antagonist activity at rat recombinant TRPV4 expressed in CHO-K1 cells assessed as blockade of 300 nM 4alphaPDD-induced calcium mobilization by FLIPR...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50195063(CHEMBL3948261)
Affinity DataIC50:  3.30E+3nMAssay Description:Antagonist activity at human recombinant TRPV4 expressed in CHO-K1 cells assessed as blockade of 1000 nM 4alphaPDD-induced calcium mobilization by FL...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50195060(CHEMBL3953003)
Affinity DataIC50:  4.30E+3nMAssay Description:Antagonist activity at human recombinant TRPV4 expressed in CHO-K1 cells assessed as blockade of 1000 nM 4alphaPDD-induced calcium mobilization by FL...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50192823(CHEMBL3906074)
Affinity DataIC50: >1.00E+4nMAssay Description:Antagonist activity at human TRPV1 expressed in CHO cells assessed as blockade of 100 nM capsaicin-induced calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50195140(CHEMBL3923579)
Affinity DataIC50: >1.00E+4nMAssay Description:Antagonist activity at human recombinant TRPV4 expressed in CHO-K1 cells assessed as blockade of 1000 nM 4alphaPDD-induced calcium mobilization by FL...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50195051(CHEMBL3941505)
Affinity DataIC50: >1.00E+4nMAssay Description:Antagonist activity at human recombinant TRPV4 expressed in CHO-K1 cells assessed as blockade of 1000 nM 4alphaPDD-induced calcium mobilization by FL...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50195136(CHEMBL3972736)
Affinity DataIC50: >1.00E+4nMAssay Description:Antagonist activity at human recombinant TRPV4 expressed in CHO-K1 cells assessed as blockade of 1000 nM 4alphaPDD-induced calcium mobilization by FL...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50195064(CHEMBL3951293)
Affinity DataIC50: >1.00E+4nMAssay Description:Antagonist activity at human recombinant TRPV4 expressed in CHO-K1 cells assessed as blockade of 1000 nM 4alphaPDD-induced calcium mobilization by FL...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50195052(CHEMBL3919377)
Affinity DataIC50:  1.00E+4nMAssay Description:Antagonist activity at human recombinant TRPV4 expressed in CHO-K1 cells assessed as blockade of 1000 nM 4alphaPDD-induced calcium mobilization by FL...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50192823(CHEMBL3906074)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed