Compile Data Set for Download or QSAR
maximum 50k data
Found 30 Enz. Inhib. hit(s) with all data for entry = 50000555
LigandPNGBDBM50253249(CHEMBL4093351)
Affinity DataIC50:  5nMAssay Description:Inhibition of PI3Kalpha (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50253251(CHEMBL4072637)
Affinity DataIC50:  6nMAssay Description:Inhibition of PI3Kalpha (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50253250(CHEMBL4064039)
Affinity DataIC50:  8nMAssay Description:Inhibition of PI3Kalpha (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50253243(CHEMBL4078681)
Affinity DataIC50: <10nMAssay Description:Inhibition of PI3Kalpha (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50094473(CHEMBL3590219)
Affinity DataIC50:  16nMAssay Description:Inhibition of PI3Kalpha (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50253251(CHEMBL4072637)
Affinity DataIC50:  16nMAssay Description:Inhibition of PI3Kdelta (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50094473(CHEMBL3590219)
Affinity DataIC50:  20nMAssay Description:Inhibition of PI3Kdelta (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50253248(CHEMBL4102957)
Affinity DataIC50:  20nMAssay Description:Inhibition of PI3Kalpha (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50253243(CHEMBL4078681)
Affinity DataIC50:  24nMAssay Description:Inhibition of PI3Kbeta (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50253249(CHEMBL4093351)
Affinity DataIC50:  32nMAssay Description:Inhibition of PI3Kbeta (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50253251(CHEMBL4072637)
Affinity DataIC50:  43nMAssay Description:Inhibition of PI3Kgamma (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50253250(CHEMBL4064039)
Affinity DataIC50:  76nMAssay Description:Agonist activity at human delta opioid receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation after 30 mins by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50253251(CHEMBL4072637)
Affinity DataIC50:  87nMAssay Description:Inhibition of PI3Kbeta (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50253249(CHEMBL4093351)
Affinity DataIC50:  200nMAssay Description:Inhibition of PI3Kbeta in PTEN-deficient human MDA-MB-468 cells assessed as reduction in AKT phosphorylation at Ser473More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50094473(CHEMBL3590219)
Affinity DataIC50:  280nMAssay Description:Inhibition of PI3Kgamma (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50253250(CHEMBL4064039)
Affinity DataIC50:  550nMAssay Description:Inhibition of PI3Kbeta in PTEN-deficient human MDA-MB-468 cells assessed as reduction in AKT phosphorylation at Ser473More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50094473(CHEMBL3590219)
Affinity DataIC50:  900nMAssay Description:Inhibition of PI3Kbeta (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50253248(CHEMBL4102957)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of human PIP5K2alpha (1 to 406 residues) by ADP Glo HTS assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50253243(CHEMBL4078681)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of PI3Kbeta in PTEN-deficient human MDA-MB-468 cells assessed as reduction in AKT phosphorylation at Ser473More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50253253(CHEMBL4065083)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of PI3Kbeta in PTEN-deficient human MDA-MB-468 cells assessed as reduction in AKT phosphorylation at Ser473More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 5-phosphate 4-kinase type-2 alpha(Homo sapiens)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50253251(CHEMBL4072637)
Affinity DataIC50:  2.60E+3nMAssay Description:Inhibition of human PI4K2alpha (1 to 479 residues) by ADP Glo HTS assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4-kinase beta(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50253251(CHEMBL4072637)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibition of human PI4KB (1 to 801 residues) by ADP Glo HTS assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50253251(CHEMBL4072637)
Affinity DataIC50:  8.40E+3nMAssay Description:Inhibition of PI3Kbeta in PTEN-deficient human MDA-MB-468 cells assessed as reduction in AKT phosphorylation at Ser473More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50094473(CHEMBL3590219)
Affinity DataIC50:  1.30E+4nMAssay Description:Inhibition of PI3Kbeta (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50253252(CHEMBL4086526)
Affinity DataIC50:  1.60E+4nMAssay Description:Inhibition of PI3Kbeta in PTEN-deficient human MDA-MB-468 cells assessed as reduction in AKT phosphorylation at Ser473More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVacuolar protein sorting-associated protein 35(Homo sapiens)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50253251(CHEMBL4072637)
Affinity DataIC50:  1.60E+4nMAssay Description:Inhibition of VPS35 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphoinositide 3-kinase regulatory subunit 4(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50253251(CHEMBL4072637)
Affinity DataIC50:  1.60E+4nMAssay Description:Inhibition of VPS15 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50253248(CHEMBL4102957)
Affinity DataIC50:  2.10E+4nMAssay Description:Inhibition of PI3Kbeta in PTEN-deficient human MDA-MB-468 cells assessed as reduction in AKT phosphorylation at Ser473More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50253251(CHEMBL4072637)
Affinity DataIC50:  2.90E+4nMAssay Description:Inhibition of m-TOR (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 5-phosphate 4-kinase type-2 alpha(Homo sapiens)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50253251(CHEMBL4072637)
Affinity DataIC50:  3.80E+4nMAssay Description:Agonist activity at human delta opioid receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation after 30 mins by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed