Compile Data Set for Download or QSAR
maximum 50k data
Found 5 Enz. Inhib. hit(s) with all data for entry = 50000106
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
University Of Porto

Curated by ChEMBL
LigandPNGBDBM50350110(CHEMBL1814068)
Affinity DataIC50:  2.90nMAssay Description:Inhibition of human MAO-B using p-tyramine as substrate by amplex red-based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
University Of Porto

Curated by ChEMBL
LigandPNGBDBM50240678(CHEMBL4077771)
Affinity DataIC50:  42nMAssay Description:Inhibition of human MAO-B using p-tyramine as substrate by amplex red-based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Porto

Curated by ChEMBL
LigandPNGBDBM50240677(CHEMBL4080202)
Affinity DataIC50:  270nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated with substrate for 15 mins followed by protein addition meas...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Porto

Curated by ChEMBL
LigandPNGBDBM50240676(CHEMBL4077452)
Affinity DataIC50:  960nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated with substrate for 15 mins followed by protein addition meas...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
University Of Porto

Curated by ChEMBL
LigandPNGBDBM50240681(CHEMBL4066788)
Affinity DataIC50:  6.84E+3nMAssay Description:Inhibition of recombinant human BACE-1 using rhodamine labelled EVNLDAEFK as substrate after 90 mins by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed