Compile Data Set for Download or QSAR
maximum 50k data
Found 22 Enz. Inhib. hit(s) with all data for entry = 50002568
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
University Of Sharjah

Curated by ChEMBL
LigandPNGBDBM50460035(CHEMBL4227505)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of CSF1R (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
University Of Sharjah

Curated by ChEMBL
LigandPNGBDBM276743(US10071991, Compound (P) | US10800764, Compound (P...)
Affinity DataIC50:  3.20nMAssay Description:Inhibition of CSF1R (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
University Of Sharjah

Curated by ChEMBL
LigandPNGBDBM50460036(CHEMBL4225509)
Affinity DataIC50:  5.5nMAssay Description:Inhibition of CSF1R (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
University Of Sharjah

Curated by ChEMBL
LigandPNGBDBM50177716(CHEMBL3813873 | US11679110, Compound Pexidartinib ...)
Affinity DataIC50:  13nMAssay Description:Inhibition of CSF1R (unknown origin)More data for this Ligand-Target Pair
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
University Of Sharjah

Curated by ChEMBL
LigandPNGBDBM50460038(CHEMBL4224714)
Affinity DataIC50:  16nMAssay Description:Inhibition of KIT (unknown origin) using biotinylated peptide substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
University Of Sharjah

Curated by ChEMBL
LigandPNGBDBM50460039(CHEMBL4229168)
Affinity DataIC50:  26nMAssay Description:Inhibition of CSF1-stimulated CSF1R (unknown origin) phosphorylation by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
University Of Sharjah

Curated by ChEMBL
LigandPNGBDBM50460038(CHEMBL4224714)
Affinity DataIC50:  28nMAssay Description:Inhibition of CSF1R (unknown origin) using biotinylated peptide substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
University Of Sharjah

Curated by ChEMBL
LigandPNGBDBM50460039(CHEMBL4229168)
Affinity DataIC50:  33nMAssay Description:Inhibition of IL34-stimulated CSF1R (unknown origin) phosphorylation by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
University Of Sharjah

Curated by ChEMBL
LigandPNGBDBM50460039(CHEMBL4229168)
Affinity DataIC50:  38nMAssay Description:Inhibition of CSF1R (unknown origin) assessed as inhibition of CSF1-stimulated cell growth by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
University Of Sharjah

Curated by ChEMBL
LigandPNGBDBM50460039(CHEMBL4229168)
Affinity DataIC50:  40nMAssay Description:Inhibition of CSF1R (unknown origin) assessed as inhibition of IL34-stimulated cell growth by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
University Of Sharjah

Curated by ChEMBL
LigandPNGBDBM50460037(CHEMBL4228766)
Affinity DataIC50:  46nMAssay Description:Inhibition of JAK2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
University Of Sharjah

Curated by ChEMBL
LigandPNGBDBM32362(5-[[3-methoxy-4-[(4-methoxyphenyl)methoxy]phenyl]m...)
Affinity DataIC50:  60nMAssay Description:Inhibition of CSF1R (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
University Of Sharjah

Curated by ChEMBL
LigandPNGBDBM50460040(CHEMBL4226338)
Affinity DataIC50:  62nMAssay Description:Inhibition of CSF1R (unknown origin) using biotinylated peptide substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
University Of Sharjah

Curated by ChEMBL
LigandPNGBDBM50460037(CHEMBL4228766)
Affinity DataIC50:  62nMAssay Description:Inhibition of FLT3 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
University Of Sharjah

Curated by ChEMBL
LigandPNGBDBM50460037(CHEMBL4228766)
Affinity DataIC50:  69nMAssay Description:Inhibition of CSF1R (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
University Of Sharjah

Curated by ChEMBL
LigandPNGBDBM50460039(CHEMBL4229168)
Affinity DataIC50:  88nMAssay Description:Inhibition of CSF1R in human monocytes assessed as inhibition of IL34-stimulated MCP releaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
University Of Sharjah

Curated by ChEMBL
LigandPNGBDBM50460039(CHEMBL4229168)
Affinity DataIC50:  93nMAssay Description:Inhibition of CSF1R in human monocytes assessed as inhibition of CSF1-stimulated MCP releaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
University Of Sharjah

Curated by ChEMBL
LigandPNGBDBM32362(5-[[3-methoxy-4-[(4-methoxyphenyl)methoxy]phenyl]m...)
Affinity DataIC50:  140nMAssay Description:Inhibition of CSF1R in human monocytes assessed as inhibition of IL34-stimulated MCP releaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
University Of Sharjah

Curated by ChEMBL
LigandPNGBDBM32362(5-[[3-methoxy-4-[(4-methoxyphenyl)methoxy]phenyl]m...)
Affinity DataIC50:  148nMAssay Description:Inhibition of CSF1R in human monocytes assessed as inhibition of CSF1-stimulated MCP releaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
University Of Sharjah

Curated by ChEMBL
LigandPNGBDBM50460037(CHEMBL4228766)
Affinity DataIC50:  230nMAssay Description:Inhibition of TYK2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
University Of Sharjah

Curated by ChEMBL
LigandPNGBDBM50460037(CHEMBL4228766)
Affinity DataIC50:  277nMAssay Description:Inhibition of CSF1R signaling in human PBMC assessed as reduction in M-CSF-induced differentiation after 7 days by immunostaining analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
University Of Sharjah

Curated by ChEMBL
LigandPNGBDBM50277584(CHEMBL482968 | N-(5-methyl-1H-pyrazol-3-yl)-6-(4-m...)
Affinity DataIC50:  600nMAssay Description:Inhibition of CSF-stimulated CSF1R phosphorylation in human MV4-11 cells by immunoblotting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed