Compile Data Set for Download or QSAR
maximum 50k data
Found 31 Enz. Inhib. hit(s) with all data for entry = 50003265
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Johannes Gutenberg-Universit£T Mainz

Curated by ChEMBL
LigandPNGBDBM50468724(CHEMBL4294334)
Affinity DataKi:  120nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesain using Z-Phe-Arg-AMC as substrate by fluorometric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Johannes Gutenberg-Universit£T Mainz

Curated by ChEMBL
LigandPNGBDBM50468723(CHEMBL4279824)
Affinity DataKi:  160nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesain using Z-Phe-Arg-AMC as substrate by fluorometric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFalcipain 2(Plasmodium falciparum)
Johannes Gutenberg-Universit£T Mainz

Curated by ChEMBL
LigandPNGBDBM50183767((2R,3R)-dibenzyl 1-((S)-1-((S)-2-(tert-butoxycarbo...)
Affinity DataKi:  400nMAssay Description:Inhibition of Plasmodium falciparum falcipain 2 using Z-Phe-Arg-AMC as substrate by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Johannes Gutenberg-Universit£T Mainz

Curated by ChEMBL
LigandPNGBDBM50183767((2R,3R)-dibenzyl 1-((S)-1-((S)-2-(tert-butoxycarbo...)
Affinity DataKi:  400nMAssay Description:Inhibition of human cathepsin-L using Z-Phe-Arg-AMC as substrate by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFalcipain 2(Plasmodium falciparum)
Johannes Gutenberg-Universit£T Mainz

Curated by ChEMBL
LigandPNGBDBM50468724(CHEMBL4294334)
Affinity DataKi:  450nMAssay Description:Inhibition of Plasmodium falciparum falcipain 2 using Z-Phe-Arg-AMC as substrate by fluorometric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Johannes Gutenberg-Universit£T Mainz

Curated by ChEMBL
LigandPNGBDBM50183767((2R,3R)-dibenzyl 1-((S)-1-((S)-2-(tert-butoxycarbo...)
Affinity DataKi:  500nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesain using Z-Phe-Arg-AMC as substrate by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCruzipain(Trypanosoma cruzi)
Johannes Gutenberg-Universit£T Mainz

Curated by ChEMBL
LigandPNGBDBM50468724(CHEMBL4294334)
Affinity DataKi:  710nMAssay Description:Inhibition of Trypanosoma cruzi cruzain using Z-Phe-Arg-AMC as substrate by fluorometric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCruzipain(Trypanosoma cruzi)
Johannes Gutenberg-Universit£T Mainz

Curated by ChEMBL
LigandPNGBDBM50183757((2S,3S)-dibenzyl 1-((S)-1-((R)-2-(tert-butoxycarbo...)
Affinity DataKi:  790nMAssay Description:Inhibition of Trypanosoma cruzi cruzain using Z-Phe-Arg-AMC as substrate by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCruzipain(Trypanosoma cruzi)
Johannes Gutenberg-Universit£T Mainz

Curated by ChEMBL
LigandPNGBDBM50183776((2S,3S)-dibenzyl 1-((R)-1-((S)-2-(tert-butoxycarbo...)
Affinity DataKi:  900nMAssay Description:Inhibition of Trypanosoma cruzi cruzain using Z-Phe-Arg-AMC as substrate by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Johannes Gutenberg-Universit£T Mainz

Curated by ChEMBL
LigandPNGBDBM50183757((2S,3S)-dibenzyl 1-((S)-1-((R)-2-(tert-butoxycarbo...)
Affinity DataKi:  1.10E+3nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesain using Z-Phe-Arg-AMC as substrate by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Johannes Gutenberg-Universit£T Mainz

Curated by ChEMBL
LigandPNGBDBM50183776((2S,3S)-dibenzyl 1-((R)-1-((S)-2-(tert-butoxycarbo...)
Affinity DataKi:  1.20E+3nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesain using Z-Phe-Arg-AMC as substrate by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFalcipain 2(Plasmodium falciparum)
Johannes Gutenberg-Universit£T Mainz

Curated by ChEMBL
LigandPNGBDBM50468723(CHEMBL4279824)
Affinity DataKi:  1.26E+3nMAssay Description:Inhibition of Plasmodium falciparum falcipain 2 using Z-Phe-Arg-AMC as substrate by fluorometric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Johannes Gutenberg-Universit£T Mainz

Curated by ChEMBL
LigandPNGBDBM50468729(CHEMBL4288606)
Affinity DataKi:  1.50E+3nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesain using Z-Phe-Arg-AMC as substrate by fluorometric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Johannes Gutenberg-Universit£T Mainz

Curated by ChEMBL
LigandPNGBDBM50468725(CHEMBL4279254)
Affinity DataKi:  1.70E+3nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesain using Z-Phe-Arg-AMC as substrate by fluorometric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCruzipain(Trypanosoma cruzi)
Johannes Gutenberg-Universit£T Mainz

Curated by ChEMBL
LigandPNGBDBM50468729(CHEMBL4288606)
Affinity DataKi:  1.80E+3nMAssay Description:Inhibition of Trypanosoma cruzi cruzain using Z-Phe-Arg-AMC as substrate by fluorometric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Johannes Gutenberg-Universit£T Mainz

Curated by ChEMBL
LigandPNGBDBM50183762((2S,3S)-dibenzyl 1-((S)-1-((S)-2-(tert-butoxycarbo...)
Affinity DataKi:  2.30E+3nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesain using Z-Phe-Arg-AMC as substrate by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Johannes Gutenberg-Universit£T Mainz

Curated by ChEMBL
LigandPNGBDBM50183747((2S,3S)-dibenzyl 1-((R)-1-((R)-2-(tert-butoxycarbo...)
Affinity DataKi:  2.80E+3nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesain using Z-Phe-Arg-AMC as substrate by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Johannes Gutenberg-Universit£T Mainz

Curated by ChEMBL
LigandPNGBDBM50183757((2S,3S)-dibenzyl 1-((S)-1-((R)-2-(tert-butoxycarbo...)
Affinity DataKi:  4.00E+3nMAssay Description:Inhibition of human cathepsin-L using Z-Phe-Arg-AMC as substrate by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCruzipain(Trypanosoma cruzi)
Johannes Gutenberg-Universit£T Mainz

Curated by ChEMBL
LigandPNGBDBM50468722(CHEMBL4292021)
Affinity DataKi:  5.50E+3nMAssay Description:Inhibition of Trypanosoma cruzi cruzain using Z-Phe-Arg-AMC as substrate by fluorometric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Johannes Gutenberg-Universit£T Mainz

Curated by ChEMBL
LigandPNGBDBM50183776((2S,3S)-dibenzyl 1-((R)-1-((S)-2-(tert-butoxycarbo...)
Affinity DataKi:  6.00E+3nMAssay Description:Inhibition of human cathepsin-L using Z-Phe-Arg-AMC as substrate by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Johannes Gutenberg-Universit£T Mainz

Curated by ChEMBL
LigandPNGBDBM50468724(CHEMBL4294334)
Affinity DataKi:  7.30E+3nMAssay Description:Inhibition of human cathepsin-L using Z-Phe-Arg-AMC as substrate by fluorometric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCruzipain(Trypanosoma cruzi)
Johannes Gutenberg-Universit£T Mainz

Curated by ChEMBL
LigandPNGBDBM50468726(CHEMBL4283566)
Affinity DataKi:  7.60E+3nMAssay Description:Inhibition of Trypanosoma cruzi cruzain using Z-Phe-Arg-AMC as substrate by fluorometric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCruzipain(Trypanosoma cruzi)
Johannes Gutenberg-Universit£T Mainz

Curated by ChEMBL
LigandPNGBDBM50468727(CHEMBL4286203)
Affinity DataKi:  7.70E+3nMAssay Description:Inhibition of Trypanosoma cruzi cruzain using Z-Phe-Arg-AMC as substrate by fluorometric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Johannes Gutenberg-Universit£T Mainz

Curated by ChEMBL
LigandPNGBDBM50468729(CHEMBL4288606)
Affinity DataKi:  1.20E+4nMAssay Description:Inhibition of human cathepsin-L using Z-Phe-Arg-AMC as substrate by fluorometric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Johannes Gutenberg-Universit£T Mainz

Curated by ChEMBL
LigandPNGBDBM50468721(CHEMBL4289948)
Affinity DataKi:  1.52E+4nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesain using Z-Phe-Arg-AMC as substrate by fluorometric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCathepsin B-like protease(Leishmania major)
Johannes Gutenberg-Universit£T Mainz

Curated by ChEMBL
LigandPNGBDBM50468725(CHEMBL4279254)
Affinity DataKi:  1.82E+4nMAssay Description:Inhibition of Leishmania major MHOM/IL/81/FE/BNI His6-tagged CPC expressed in Pichia pastoris using Cbz-Phe-Arg-AMC as substrate by fluorescence spec...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFalcipain 2(Plasmodium falciparum)
Johannes Gutenberg-Universit£T Mainz

Curated by ChEMBL
LigandPNGBDBM50183757((2S,3S)-dibenzyl 1-((S)-1-((R)-2-(tert-butoxycarbo...)
Affinity DataKi:  2.83E+4nMAssay Description:Inhibition of Plasmodium falciparum falcipain 2 using Z-Phe-Arg-AMC as substrate by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFalcipain 2(Plasmodium falciparum)
Johannes Gutenberg-Universit£T Mainz

Curated by ChEMBL
LigandPNGBDBM50468728(CHEMBL4290479)
Affinity DataKi:  2.86E+4nMAssay Description:Inhibition of Plasmodium falciparum falcipain 2 using Z-Phe-Arg-AMC as substrate by fluorometric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCruzipain(Trypanosoma cruzi)
Johannes Gutenberg-Universit£T Mainz

Curated by ChEMBL
LigandPNGBDBM50468721(CHEMBL4289948)
Affinity DataKi:  3.09E+4nMAssay Description:Inhibition of Trypanosoma cruzi cruzain using Z-Phe-Arg-AMC as substrate by fluorometric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFalcipain 2(Plasmodium falciparum)
Johannes Gutenberg-Universit£T Mainz

Curated by ChEMBL
LigandPNGBDBM50183776((2S,3S)-dibenzyl 1-((R)-1-((S)-2-(tert-butoxycarbo...)
Affinity DataKi:  4.39E+4nMAssay Description:Inhibition of Plasmodium falciparum falcipain 2 using Z-Phe-Arg-AMC as substrate by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
Johannes Gutenberg-Universit£T Mainz

Curated by ChEMBL
LigandPNGBDBM50183767((2R,3R)-dibenzyl 1-((S)-1-((S)-2-(tert-butoxycarbo...)
Affinity DataKi:  1.14E+5nMAssay Description:Inhibition of human cathepsin-B using Z-Phe-Arg-AMC as substrate by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed