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Found 35 Enz. Inhib. hit(s) with all data for entry = 50003074
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM80642(CHEMBL191491 | MG 624 | MLS002172460 | SMR00125409...)
Affinity DataKi:  104nMAssay Description:Displacement of [125I]-alpha-bungarotoxin from human alpha7 nAChR expressed in human SH-SY5Y cell membranes after 30 mins by gamma counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50466608(CHEMBL4285772)
Affinity DataKi:  164nMAssay Description:Displacement of [125I]-alpha-bungarotoxin from human alpha7 nAChR expressed in human SH-SY5Y cell membranes after 30 mins by gamma counting analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50466614(CHEMBL4291079)
Affinity DataKi:  186nMAssay Description:Displacement of [125I]-alpha-bungarotoxin from human alpha7 nAChR expressed in human SH-SY5Y cell membranes after 30 mins by gamma counting analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50466613(CHEMBL4287656)
Affinity DataKi:  189nMAssay Description:Displacement of [125I]-alpha-bungarotoxin from human alpha7 nAChR expressed in human SH-SY5Y cell membranes after 30 mins by gamma counting analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50466606(CHEMBL4280452)
Affinity DataKi:  305nMAssay Description:Displacement of [125I]-alpha-bungarotoxin from human alpha7 nAChR expressed in human SH-SY5Y cell membranes after 30 mins by gamma counting analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50466607(CHEMBL4293646)
Affinity DataKi:  465nMAssay Description:Displacement of [125I]-alpha-bungarotoxin from human alpha7 nAChR expressed in human SH-SY5Y cell membranes after 30 mins by gamma counting analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50466603(CHEMBL4277852)
Affinity DataKi:  559nMAssay Description:Displacement of [125I]-alpha-bungarotoxin from human alpha7 nAChR expressed in human SH-SY5Y cell membranes after 30 mins by gamma counting analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50466615(CHEMBL4291927)
Affinity DataKi:  617nMAssay Description:Displacement of [125I]-alpha-bungarotoxin from human alpha7 nAChR expressed in human SH-SY5Y cell membranes after 30 mins by gamma counting analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50466611(CHEMBL4281312)
Affinity DataKi:  909nMAssay Description:Displacement of [125I]-alpha-bungarotoxin from human alpha7 nAChR expressed in human SH-SY5Y cell membranes after 30 mins by gamma counting analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50466616(CHEMBL4288118)
Affinity DataKi:  984nMAssay Description:Displacement of [125I]-alpha-bungarotoxin from human alpha7 nAChR expressed in human SH-SY5Y cell membranes after 30 mins by gamma counting analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50466612(CHEMBL4290427)
Affinity DataKi:  1.29E+3nMAssay Description:Displacement of [125I]-alpha-bungarotoxin from human alpha7 nAChR expressed in human SH-SY5Y cell membranes after 30 mins by gamma counting analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50466609(CHEMBL4284717)
Affinity DataKi:  1.64E+3nMAssay Description:Displacement of [125I]-alpha-bungarotoxin from human alpha7 nAChR expressed in human SH-SY5Y cell membranes after 30 mins by gamma counting analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50466605(CHEMBL4276776)
Affinity DataKi:  1.83E+3nMAssay Description:Displacement of [125I]-alpha-bungarotoxin from human alpha7 nAChR expressed in human SH-SY5Y cell membranes after 30 mins by gamma counting analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50466604(CHEMBL4280206)
Affinity DataKi:  1.93E+3nMAssay Description:Displacement of [125I]-alpha-bungarotoxin from human alpha7 nAChR expressed in human SH-SY5Y cell membranes after 30 mins by gamma counting analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50466610(CHEMBL4288506)
Affinity DataKi:  2.80E+3nMAssay Description:Displacement of [125I]-alpha-bungarotoxin from human alpha7 nAChR expressed in human SH-SY5Y cell membranes after 30 mins by gamma counting analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50466614(CHEMBL4291079)
Affinity DataKi: >3.00E+3nMAssay Description:Displacement of (+/-)-[3H]-epibatidine from human alpha4beta2 nAChR expressed in HEK293 cell membranes after 30 mins by beta counting analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50466609(CHEMBL4284717)
Affinity DataKi: >3.00E+3nMAssay Description:Displacement of (+/-)-[3H]-epibatidine from human alpha4beta2 nAChR expressed in HEK293 cell membranes after 30 mins by beta counting analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50466607(CHEMBL4293646)
Affinity DataKi: >3.00E+3nMAssay Description:Displacement of (+/-)-[3H]-epibatidine from human alpha4beta2 nAChR expressed in HEK293 cell membranes after 30 mins by beta counting analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM80642(CHEMBL191491 | MG 624 | MLS002172460 | SMR00125409...)
Affinity DataKi: >3.00E+3nMAssay Description:Displacement of (+/-)-[3H]-epibatidine from human alpha4beta2 nAChR expressed in HEK293 cell membranes after 30 mins by beta counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50466608(CHEMBL4285772)
Affinity DataKi: >3.00E+3nMAssay Description:Displacement of (+/-)-[3H]-epibatidine from human alpha4beta2 nAChR expressed in HEK293 cell membranes after 30 mins by beta counting analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50466604(CHEMBL4280206)
Affinity DataKi: >3.00E+3nMAssay Description:Displacement of (+/-)-[3H]-epibatidine from human alpha4beta2 nAChR expressed in HEK293 cell membranes after 30 mins by beta counting analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50466607(CHEMBL4293646)
Affinity DataIC50:  4.80nMAssay Description:Antagonist activity at human alpha9alpha10 nACHR expressed in xenopous laevis oocyte assessed as inhibition of ACh-induced channel current after 5 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50466614(CHEMBL4291079)
Affinity DataIC50:  5nMAssay Description:Antagonist activity at human alpha9alpha10 nACHR expressed in xenopous laevis oocyte assessed as inhibition of ACh-induced channel current after 5 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50466614(CHEMBL4291079)
Affinity DataIC50:  6.5nMAssay Description:Antagonist activity at human alpha7 nACHR expressed in xenopous laevis oocyte assessed as inhibition of ACh-induced channel current after 5 mins at -...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50466608(CHEMBL4285772)
Affinity DataIC50:  6.60nMAssay Description:Antagonist activity at human alpha9alpha10 nACHR expressed in xenopous laevis oocyte assessed as inhibition of ACh-induced channel current after 5 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM80642(CHEMBL191491 | MG 624 | MLS002172460 | SMR00125409...)
Affinity DataIC50:  10nMAssay Description:Antagonist activity at human alpha9alpha10 nACHR expressed in xenopous laevis oocyte assessed as inhibition of ACh-induced channel current after 5 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50466606(CHEMBL4280452)
Affinity DataIC50:  12nMAssay Description:Antagonist activity at human alpha9alpha10 nACHR expressed in xenopous laevis oocyte assessed as inhibition of ACh-induced channel current after 5 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50466607(CHEMBL4293646)
Affinity DataIC50:  12nMAssay Description:Antagonist activity at human alpha7 nACHR expressed in xenopous laevis oocyte assessed as inhibition of ACh-induced channel current after 5 mins at -...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50466613(CHEMBL4287656)
Affinity DataIC50:  17nMAssay Description:Antagonist activity at human alpha9alpha10 nACHR expressed in xenopous laevis oocyte assessed as inhibition of ACh-induced channel current after 5 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50466606(CHEMBL4280452)
Affinity DataIC50:  24nMAssay Description:Antagonist activity at human alpha7 nACHR expressed in xenopous laevis oocyte assessed as inhibition of ACh-induced channel current after 5 mins at -...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM80642(CHEMBL191491 | MG 624 | MLS002172460 | SMR00125409...)
Affinity DataIC50:  41nMAssay Description:Antagonist activity at human alpha7 nACHR expressed in xenopous laevis oocyte assessed as inhibition of ACh-induced channel current after 5 mins at -...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50466613(CHEMBL4287656)
Affinity DataIC50:  47nMAssay Description:Antagonist activity at human alpha7 nACHR expressed in xenopous laevis oocyte assessed as inhibition of ACh-induced channel current after 5 mins at -...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50466608(CHEMBL4285772)
Affinity DataIC50:  92nMAssay Description:Antagonist activity at human alpha7 nACHR expressed in xenopous laevis oocyte assessed as inhibition of ACh-induced channel current after 5 mins at -...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50466605(CHEMBL4276776)
Affinity DataIC50: >1.00E+4nMAssay Description:Antagonist activity at human alpha9alpha10 nACHR expressed in xenopous laevis oocyte assessed as inhibition of ACh-induced channel current after 5 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50466605(CHEMBL4276776)
Affinity DataIC50: >1.00E+4nMAssay Description:Antagonist activity at human alpha7 nACHR expressed in xenopous laevis oocyte assessed as inhibition of ACh-induced channel current after 5 mins at -...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed