Compile Data Set for Download or QSAR
maximum 50k data
Found 48 Enz. Inhib. hit(s) with all data for entry = 8814
TargetReplicase polyprotein 1ab(2019-nCoV)
National Institutes Of Health

LigandPNGBDBM50438912(CHEMBL1096283 | CVD-0012826 | MAT-POS-1e0c1c67-1 |...)
Affinity DataIC50:  260nMAssay Description:The 3CLpro enzyme assay was developed in 384-well black, medium binding microplates (Greiner Bio-One, Monroe, NC, USA) with a total volume of 20 _...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
National Institutes Of Health

LigandPNGBDBM420306(DA-3003-1)
Affinity DataIC50:  2.63E+3nMAssay Description:The 3CLpro enzyme assay was developed in 384-well black, medium binding microplates (Greiner Bio-One, Monroe, NC, USA) with a total volume of 20 _...More data for this Ligand-Target Pair
Ligand InfoPurchasePDB
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
National Institutes Of Health

LigandPNGBDBM420299(Hydroxocobalamin)
Affinity DataIC50:  3.29E+3nMAssay Description:The 3CLpro enzyme assay was developed in 384-well black, medium binding microplates (Greiner Bio-One, Monroe, NC, USA) with a total volume of 20 _...More data for this Ligand-Target Pair
Ligand InfoPurchase
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
National Institutes Of Health

LigandPNGBDBM50000029(4-Methyl-8-{4-methyl-3-[3-(3-{3-[2-methyl-5-(4,6,8...)
Affinity DataIC50:  6.50E+3nMAssay Description:The 3CLpro enzyme assay was developed in 384-well black, medium binding microplates (Greiner Bio-One, Monroe, NC, USA) with a total volume of 20 _...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
National Institutes Of Health

LigandPNGBDBM228619(US9345789, Z-DEVD-FMK)
Affinity DataIC50:  6.81E+3nMAssay Description:The 3CLpro enzyme assay was developed in 384-well black, medium binding microplates (Greiner Bio-One, Monroe, NC, USA) with a total volume of 20 _...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
National Institutes Of Health

LigandPNGBDBM420307(CAY-10581)
Affinity DataIC50:  9.20E+3nMAssay Description:The 3CLpro enzyme assay was developed in 384-well black, medium binding microplates (Greiner Bio-One, Monroe, NC, USA) with a total volume of 20 _...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
National Institutes Of Health

LigandPNGBDBM420304(LLL-12)
Affinity DataIC50:  9.84E+3nMAssay Description:The 3CLpro enzyme assay was developed in 384-well black, medium binding microplates (Greiner Bio-One, Monroe, NC, USA) with a total volume of 20 _...More data for this Ligand-Target Pair
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In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
National Institutes Of Health

LigandPNGBDBM59087(CHEMBL258765 | Fasca-plysi | Fascaplysin)
Affinity DataIC50:  9.96E+3nMAssay Description:The 3CLpro enzyme assay was developed in 384-well black, medium binding microplates (Greiner Bio-One, Monroe, NC, USA) with a total volume of 20 _...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
National Institutes Of Health

LigandPNGBDBM50240436(2-Hydroxy-6-pentadecyl-benzoic acid | 2-hydroxy-6-...)
Affinity DataIC50:  1.10E+4nMAssay Description:The 3CLpro enzyme assay was developed in 384-well black, medium binding microplates (Greiner Bio-One, Monroe, NC, USA) with a total volume of 20 _...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
National Institutes Of Health

LigandPNGBDBM420305(Z-FA-FM | Z-FA-FMK)
Affinity DataIC50:  1.14E+4nMAssay Description:The 3CLpro enzyme assay was developed in 384-well black, medium binding microplates (Greiner Bio-One, Monroe, NC, USA) with a total volume of 20 _...More data for this Ligand-Target Pair
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In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
National Institutes Of Health

LigandPNGBDBM420309(MG-115)
Affinity DataIC50:  1.27E+4nMAssay Description:The 3CLpro enzyme assay was developed in 384-well black, medium binding microplates (Greiner Bio-One, Monroe, NC, USA) with a total volume of 20 _...More data for this Ligand-Target Pair
Ligand InfoPurchase
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
National Institutes Of Health

LigandPNGBDBM81348(β-Lapachone (A3) | Beta lapachone | R115 (Rea...)
Affinity DataIC50:  1.33E+4nMAssay Description:The 3CLpro enzyme assay was developed in 384-well black, medium binding microplates (Greiner Bio-One, Monroe, NC, USA) with a total volume of 20 _...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
National Institutes Of Health

LigandPNGBDBM420311(Sepantronium bromide)
Affinity DataIC50:  1.36E+4nMAssay Description:The 3CLpro enzyme assay was developed in 384-well black, medium binding microplates (Greiner Bio-One, Monroe, NC, USA) with a total volume of 20 _...More data for this Ligand-Target Pair
Ligand InfoPurchaseMCE
PDB
TargetReplicase polyprotein 1ab(2019-nCoV)
National Institutes Of Health

LigandPNGBDBM50208827(2,3-bis(2-hydroxyethylthio)naphthalene-1,4-dione |...)
Affinity DataIC50:  1.79E+4nMAssay Description:The 3CLpro enzyme assay was developed in 384-well black, medium binding microplates (Greiner Bio-One, Monroe, NC, USA) with a total volume of 20 _...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
National Institutes Of Health

LigandPNGBDBM420313(Vitamin B12)
Affinity DataIC50:  1.80E+4nMAssay Description:The 3CLpro enzyme assay was developed in 384-well black, medium binding microplates (Greiner Bio-One, Monroe, NC, USA) with a total volume of 20 _...More data for this Ligand-Target Pair
Ligand InfoPurchase
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
National Institutes Of Health

LigandPNGBDBM420314(4E1-RCat | 4E1RCat)
Affinity DataIC50:  1.83E+4nMAssay Description:The 3CLpro enzyme assay was developed in 384-well black, medium binding microplates (Greiner Bio-One, Monroe, NC, USA) with a total volume of 20 _...More data for this Ligand-Target Pair
Ligand InfoPurchase
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
National Institutes Of Health

LigandPNGBDBM420325(Adomeg-livan | Adomeglivant)
Affinity DataIC50:  1.92E+4nMAssay Description:The 3CLpro enzyme assay was developed in 384-well black, medium binding microplates (Greiner Bio-One, Monroe, NC, USA) with a total volume of 20 _...More data for this Ligand-Target Pair
Ligand InfoPurchase
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
National Institutes Of Health

LigandPNGBDBM420315(TBB)
Affinity DataIC50:  2.05E+4nMAssay Description:The 3CLpro enzyme assay was developed in 384-well black, medium binding microplates (Greiner Bio-One, Monroe, NC, USA) with a total volume of 20 _...More data for this Ligand-Target Pair
Ligand InfoPurchase
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
National Institutes Of Health

LigandPNGBDBM31712(HEXACHLOROPHENE | Hexach-lorophene | MLS000028433 ...)
Affinity DataIC50:  2.15E+4nMAssay Description:The 3CLpro enzyme assay was developed in 384-well black, medium binding microplates (Greiner Bio-One, Monroe, NC, USA) with a total volume of 20 _...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
National Institutes Of Health

LigandPNGBDBM50006805(3-(1-(4-chlorobenzyl)-3-(tert-butylthio)-5-isoprop...)
Affinity DataIC50:  2.15E+4nMAssay Description:The 3CLpro enzyme assay was developed in 384-well black, medium binding microplates (Greiner Bio-One, Monroe, NC, USA) with a total volume of 20 _...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
National Institutes Of Health

LigandPNGBDBM19992(2-[3-[3-[[2-chloro-3-(trifluoromethyl)phenyl]methy...)
Affinity DataIC50:  2.15E+4nMAssay Description:The 3CLpro enzyme assay was developed in 384-well black, medium binding microplates (Greiner Bio-One, Monroe, NC, USA) with a total volume of 20 _...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
National Institutes Of Health

LigandPNGBDBM50289149(GW305074X | GW5074 | US10570155, GW5074 | US113324...)
Affinity DataIC50:  2.15E+4nMAssay Description:The 3CLpro enzyme assay was developed in 384-well black, medium binding microplates (Greiner Bio-One, Monroe, NC, USA) with a total volume of 20 _...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
National Institutes Of Health

LigandPNGBDBM50248106(CHEMBL461101 | ELTROMBOPAG | Eltrombopag olamine)
Affinity DataIC50:  2.15E+4nMAssay Description:The 3CLpro enzyme assay was developed in 384-well black, medium binding microplates (Greiner Bio-One, Monroe, NC, USA) with a total volume of 20 _...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
National Institutes Of Health

LigandPNGBDBM50127222(CHEMBL38508 | GW-0742 | {4-[2-(3-Fluoro-4-trifluor...)
Affinity DataIC50:  2.23E+4nMAssay Description:The 3CLpro enzyme assay was developed in 384-well black, medium binding microplates (Greiner Bio-One, Monroe, NC, USA) with a total volume of 20 _...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
National Institutes Of Health

LigandPNGBDBM50285551(3-Carboxy-2-hexadecyl-3-hydroxy-pentanedioic acid ...)
Affinity DataIC50:  2.35E+4nMAssay Description:The 3CLpro enzyme assay was developed in 384-well black, medium binding microplates (Greiner Bio-One, Monroe, NC, USA) with a total volume of 20 _...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
National Institutes Of Health

LigandPNGBDBM420318(Oritavancin (diphosphate))
Affinity DataIC50:  2.42E+4nMAssay Description:The 3CLpro enzyme assay was developed in 384-well black, medium binding microplates (Greiner Bio-One, Monroe, NC, USA) with a total volume of 20 _...More data for this Ligand-Target Pair
Ligand InfoPurchase
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
National Institutes Of Health

LigandPNGBDBM420331(AMG-837)
Affinity DataIC50:  2.42E+4nMAssay Description:The 3CLpro enzyme assay was developed in 384-well black, medium binding microplates (Greiner Bio-One, Monroe, NC, USA) with a total volume of 20 _...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
National Institutes Of Health

LigandPNGBDBM50168081(CHEMBL3799802 | MK 0893)
Affinity DataIC50:  2.43E+4nMAssay Description:The 3CLpro enzyme assay was developed in 384-well black, medium binding microplates (Greiner Bio-One, Monroe, NC, USA) with a total volume of 20 _...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
National Institutes Of Health

LigandPNGBDBM420320(SU 16f)
Affinity DataIC50:  2.50E+4nMAssay Description:The 3CLpro enzyme assay was developed in 384-well black, medium binding microplates (Greiner Bio-One, Monroe, NC, USA) with a total volume of 20 _...More data for this Ligand-Target Pair
Ligand InfoPurchase
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
National Institutes Of Health

LigandPNGBDBM50360449(CHEMBL1215739 | MG-149)
Affinity DataIC50:  2.71E+4nMAssay Description:The 3CLpro enzyme assay was developed in 384-well black, medium binding microplates (Greiner Bio-One, Monroe, NC, USA) with a total volume of 20 _...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
National Institutes Of Health

LigandPNGBDBM420321(Penta-O-galloyl-beta-D-glucose hydrate)
Affinity DataIC50:  2.78E+4nMAssay Description:The 3CLpro enzyme assay was developed in 384-well black, medium binding microplates (Greiner Bio-One, Monroe, NC, USA) with a total volume of 20 _...More data for this Ligand-Target Pair
Ligand InfoPurchasePDB
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
National Institutes Of Health

LigandPNGBDBM50062648(2-Chloro-4-trifluoromethyl-pyrimidine-5-carboxylic...)
Affinity DataIC50:  2.89E+4nMAssay Description:The 3CLpro enzyme assay was developed in 384-well black, medium binding microplates (Greiner Bio-One, Monroe, NC, USA) with a total volume of 20 _...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
National Institutes Of Health

LigandPNGBDBM50168081(CHEMBL3799802 | MK 0893)
Affinity DataEC50:  3.16E+3nMAssay Description:SARS-CoV-2 CPE assay was conducted at Southern Research Institute (Birmingham, AL) as described in previous reports30, 31. In brief, high ACE2 expres...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
National Institutes Of Health

LigandPNGBDBM50248106(CHEMBL461101 | ELTROMBOPAG | Eltrombopag olamine)
Affinity DataEC50:  8.91E+3nMAssay Description:SARS-CoV-2 CPE assay was conducted at Southern Research Institute (Birmingham, AL) as described in previous reports30, 31. In brief, high ACE2 expres...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
National Institutes Of Health

LigandPNGBDBM420315(TBB)
Affinity DataEC50:  1.41E+4nMAssay Description:SARS-CoV-2 CPE assay was conducted at Southern Research Institute (Birmingham, AL) as described in previous reports30, 31. In brief, high ACE2 expres...More data for this Ligand-Target Pair
Ligand InfoPurchase
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
National Institutes Of Health

LigandPNGBDBM19992(2-[3-[3-[[2-chloro-3-(trifluoromethyl)phenyl]methy...)
Affinity DataEC50:  3.55E+3nMAssay Description:SARS-CoV-2 CPE assay was conducted at Southern Research Institute (Birmingham, AL) as described in previous reports30, 31. In brief, high ACE2 expres...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
National Institutes Of Health

LigandPNGBDBM420309(MG-115)
Affinity DataEC50:  23nMAssay Description:SARS-CoV-2 CPE assay was conducted at Southern Research Institute (Birmingham, AL) as described in previous reports30, 31. In brief, high ACE2 expres...More data for this Ligand-Target Pair
Ligand InfoPurchase
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
National Institutes Of Health

LigandPNGBDBM50289149(GW305074X | GW5074 | US10570155, GW5074 | US113324...)
Affinity DataEC50:  1.12E+4nMAssay Description:SARS-CoV-2 CPE assay was conducted at Southern Research Institute (Birmingham, AL) as described in previous reports30, 31. In brief, high ACE2 expres...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
National Institutes Of Health

LigandPNGBDBM420306(DA-3003-1)
Affinity DataEC50:  4.47E+3nMAssay Description:SARS-CoV-2 CPE assay was conducted at Southern Research Institute (Birmingham, AL) as described in previous reports30, 31. In brief, high ACE2 expres...More data for this Ligand-Target Pair
Ligand InfoPurchasePDB
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
National Institutes Of Health

LigandPNGBDBM31712(HEXACHLOROPHENE | Hexach-lorophene | MLS000028433 ...)
Affinity DataEC50:  790nMAssay Description:SARS-CoV-2 CPE assay was conducted at Southern Research Institute (Birmingham, AL) as described in previous reports30, 31. In brief, high ACE2 expres...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
National Institutes Of Health

LigandPNGBDBM420305(Z-FA-FM | Z-FA-FMK)
Affinity DataEC50:  130nMAssay Description:SARS-CoV-2 CPE assay was conducted at Southern Research Institute (Birmingham, AL) as described in previous reports30, 31. In brief, high ACE2 expres...More data for this Ligand-Target Pair
Ligand InfoPurchase
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
National Institutes Of Health

LigandPNGBDBM50006805(3-(1-(4-chlorobenzyl)-3-(tert-butylthio)-5-isoprop...)
Affinity DataEC50:  1.12E+4nMAssay Description:SARS-CoV-2 CPE assay was conducted at Southern Research Institute (Birmingham, AL) as described in previous reports30, 31. In brief, high ACE2 expres...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
National Institutes Of Health

LigandPNGBDBM50438912(CHEMBL1096283 | CVD-0012826 | MAT-POS-1e0c1c67-1 |...)
Affinity DataEC50:  3.55E+3nMAssay Description:SARS-CoV-2 CPE assay was conducted at Southern Research Institute (Birmingham, AL) as described in previous reports30, 31. In brief, high ACE2 expres...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
National Institutes Of Health

LigandPNGBDBM420331(AMG-837)
Affinity DataEC50:  1.12E+4nMAssay Description:SARS-CoV-2 CPE assay was conducted at Southern Research Institute (Birmingham, AL) as described in previous reports30, 31. In brief, high ACE2 expres...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
National Institutes Of Health

LigandPNGBDBM50360449(CHEMBL1215739 | MG-149)
Affinity DataEC50:  1.26E+4nMAssay Description:SARS-CoV-2 CPE assay was conducted at Southern Research Institute (Birmingham, AL) as described in previous reports30, 31. In brief, high ACE2 expres...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
National Institutes Of Health

LigandPNGBDBM420325(Adomeg-livan | Adomeglivant)
Affinity DataEC50:  3.16E+3nMAssay Description:SARS-CoV-2 CPE assay was conducted at Southern Research Institute (Birmingham, AL) as described in previous reports30, 31. In brief, high ACE2 expres...More data for this Ligand-Target Pair
Ligand InfoPurchase
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
National Institutes Of Health

LigandPNGBDBM420321(Penta-O-galloyl-beta-D-glucose hydrate)
Affinity DataEC50:  1.26E+4nMAssay Description:SARS-CoV-2 CPE assay was conducted at Southern Research Institute (Birmingham, AL) as described in previous reports30, 31. In brief, high ACE2 expres...More data for this Ligand-Target Pair
Ligand InfoPurchasePDB
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
National Institutes Of Health

LigandPNGBDBM50240436(2-Hydroxy-6-pentadecyl-benzoic acid | 2-hydroxy-6-...)
Affinity DataEC50:  3.98E+3nMAssay Description:SARS-CoV-2 CPE assay was conducted at Southern Research Institute (Birmingham, AL) as described in previous reports30, 31. In brief, high ACE2 expres...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed