Compile Data Set for Download or QSAR
maximum 50k data
Found 44 Enz. Inhib. hit(s) with all data for entry = 50035740
TargetAdenosine receptor A1(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)
Affinity DataKi:  0.800nMAssay Description:Displacement of [3H]PIA from adenosine A1 receptor of rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50118810((2R,3S,4R,5R)-2-(hydroxymethyl)-5-(6-((R)-1-phenyl...)
Affinity DataKi:  1.30nMAssay Description:Displacement of [3H]PIA from adenosine A1 receptor of rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50407524(CHEMBL2113390)
Affinity DataKi:  1.60nMAssay Description:Displacement of [3H]PIA from adenosine A1 receptor of rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50407529(CHEMBL2113389)
Affinity DataKi:  7.5nMAssay Description:Displacement of [3H]PIA from adenosine A1 receptor of rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50367681(CHEMBL606016)
Affinity DataKi:  7.70nMAssay Description:Inhibition of Adenylate cyclase activity in rat fat cell membrane at adenosine A1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM21220((2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-N-ethyl-3,...)
Affinity DataKi:  8.20nMAssay Description:Displacement of [3H]PIA from adenosine A1 receptor of rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50407525(CHEMBL2113387)
Affinity DataKi:  16nMAssay Description:Displacement of [3H]PIA from adenosine A1 receptor of rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50367680(CHEMBL605008)
Affinity DataKi:  18nMAssay Description:Displacement of [3H]PIA from adenosine A1 receptor of rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
Universit£

Curated by ChEMBL
LigandPNGBDBM21220((2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-N-ethyl-3,...)
Affinity DataKi:  22nMAssay Description:Displacement of [3H]NECA from A2-receptor of rat striatal membranesMore data for this Ligand-Target Pair
TargetAdenosine receptor A1(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50407526(CHEMBL2113391)
Affinity DataKi:  47nMAssay Description:Displacement of [3H]PIA from adenosine A1 receptor of rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50452519(CHEMBL2113396)
Affinity DataKi:  51nMAssay Description:Displacement of [3H]PIA from adenosine A1 receptor of rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50060165((2R,3R,4S,5R)-2-(7-Amino-imidazo[4,5-b]pyridin-3-y...)
Affinity DataKi:  115nMAssay Description:Displacement of [3H]PIA from adenosine A1 receptor of rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50452519(CHEMBL2113396)
Affinity DataKi:  580nMAssay Description:Displacement of [3H]NECA from A2-receptor of rat striatal membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50118810((2R,3S,4R,5R)-2-(hydroxymethyl)-5-(6-((R)-1-phenyl...)
Affinity DataKi:  730nMAssay Description:Displacement of [3H]NECA from A2-receptor of rat striatal membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
Universit£

Curated by ChEMBL
LigandPNGBDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)
Affinity DataKi:  2.00E+3nMAssay Description:Inhibition of Adenylate cyclase activity in rat fat cell membrane at adenosine A1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50060165((2R,3R,4S,5R)-2-(7-Amino-imidazo[4,5-b]pyridin-3-y...)
Affinity DataKi:  2.90E+3nMAssay Description:Displacement of [3H]NECA from A2-receptor of rat striatal membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50367680(CHEMBL605008)
Affinity DataKi:  3.70E+3nMAssay Description:Displacement of [3H]NECA from A2-receptor of rat striatal membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50367681(CHEMBL606016)
Affinity DataKi:  4.90E+3nMAssay Description:Displacement of [3H]PIA from adenosine A1 receptor of rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50407525(CHEMBL2113387)
Affinity DataKi:  6.80E+3nMAssay Description:Displacement of [3H]NECA from A2-receptor of rat striatal membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50407526(CHEMBL2113391)
Affinity DataKi:  8.20E+3nMAssay Description:Inhibition of Adenylate cyclase activity in rat fat cell membrane at adenosine A1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50407524(CHEMBL2113390)
Affinity DataKi:  1.32E+4nMAssay Description:Inhibition of Adenylate cyclase activity in rat fat cell membrane at adenosine A1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50407529(CHEMBL2113389)
Affinity DataKi:  1.76E+4nMAssay Description:Displacement of [3H]PIA from adenosine A1 receptor of rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50118810((2R,3S,4R,5R)-2-(hydroxymethyl)-5-(6-((R)-1-phenyl...)
Affinity DataIC50:  40nMAssay Description:Inhibition of Adenylate cyclase activity in rat fat cell membrane at adenosine A1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)
Affinity DataIC50:  58nMAssay Description:Inhibition of Adenylate cyclase activity in rat fat cell membrane at adenosine A1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM21220((2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-N-ethyl-3,...)
Affinity DataIC50:  200nMAssay Description:Inhibition of Adenylate cyclase activity in rat fat cell membrane at adenosine A1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50407524(CHEMBL2113390)
Affinity DataIC50:  360nMAssay Description:Inhibition of Adenylate cyclase activity in rat fat cell membrane at adenosine A1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50367681(CHEMBL606016)
Affinity DataIC50:  630nMAssay Description:Inhibition of Adenylate cyclase activity in rat fat cell membrane at adenosine A1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50367680(CHEMBL605008)
Affinity DataIC50:  960nMAssay Description:Inhibition of Adenylate cyclase activity in rat fat cell membrane at adenosine A1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50407529(CHEMBL2113389)
Affinity DataIC50:  970nMAssay Description:Inhibition of Adenylate cyclase activity in rat fat cell membrane at adenosine A1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50452519(CHEMBL2113396)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of Adenylate cyclase activity in rat fat cell membrane at adenosine A1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50407525(CHEMBL2113387)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of Adenylate cyclase activity in rat fat cell membrane at adenosine A1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50407526(CHEMBL2113391)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibition of Adenylate cyclase activity in rat fat cell membrane at adenosine A1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50060165((2R,3R,4S,5R)-2-(7-Amino-imidazo[4,5-b]pyridin-3-y...)
Affinity DataIC50:  6.70E+3nMAssay Description:Inhibition of Adenylate cyclase activity in rat fat cell membrane at adenosine A1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a/A2b(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50407526(CHEMBL2113391)
Affinity DataEC50:  4.80E+3nMAssay Description:Stimulation of adenylate cyclase activity in human platelet membrane at A2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a/A2b(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)
Affinity DataEC50:  2.20E+3nMAssay Description:Stimulation of adenylate cyclase activity in human platelet membrane at A2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a/A2b(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM21220((2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-N-ethyl-3,...)
Affinity DataEC50:  260nMAssay Description:Stimulation of adenylate cyclase activity in human platelet membrane at A2 receptorMore data for this Ligand-Target Pair
TargetAdenosine receptor A2a/A2b(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50367680(CHEMBL605008)
Affinity DataEC50:  3.50E+3nMAssay Description:Stimulation of adenylate cyclase activity in human platelet membrane at A2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a/A2b(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50367681(CHEMBL606016)
Affinity DataEC50:  6.60E+3nMAssay Description:Stimulation of adenylate cyclase activity in human platelet membrane at A2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a/A2b(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50060165((2R,3R,4S,5R)-2-(7-Amino-imidazo[4,5-b]pyridin-3-y...)
Affinity DataEC50:  1.80E+4nMAssay Description:Stimulation of adenylate cyclase activity in human platelet membrane at A2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a/A2b(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50407525(CHEMBL2113387)
Affinity DataEC50:  2.00E+4nMAssay Description:Inhibition of Adenylate cyclase activity in rat fat cell membrane at adenosine A1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a/A2b(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50118810((2R,3S,4R,5R)-2-(hydroxymethyl)-5-(6-((R)-1-phenyl...)
Affinity DataEC50:  950nMAssay Description:Inhibition of Adenylate cyclase activity in rat fat cell membrane at adenosine A1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a/A2b(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50407524(CHEMBL2113390)
Affinity DataEC50:  2.80E+4nMAssay Description:Stimulation of adenylate cyclase activity in human platelet membrane at A2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a/A2b(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50452519(CHEMBL2113396)
Affinity DataEC50:  2.80E+3nMAssay Description:Stimulation of adenylate cyclase activity in human platelet membrane at A2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a/A2b(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50407529(CHEMBL2113389)
Affinity DataEC50:  2.60E+4nMAssay Description:Stimulation of adenylate cyclase activity in human platelet membrane at A2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed