Compile Data Set for Download or QSAR
maximum 50k data
Found 22 Enz. Inhib. hit(s) with all data for entry = 50034842
TargetAngiotensin-converting enzyme(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50287432((S)-2-[(1-{Hydroxy-[(R)-1-(4-nitro-benzoylamino)-2...)
Affinity DataIC50:  1.5nMAssay Description:Compound was measured for the inhibition of Angiotensin I converting enzymeMore data for this Ligand-Target Pair
In DepthDetails Article
TargetAngiotensin-converting enzyme(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50287430((S)-2-[(1-{[(R)-1-((S)-6-Amino-2-methanesulfonylam...)
Affinity DataIC50:  2.5nMAssay Description:Compound was measured for the inhibition of Angiotensin I converting enzymeMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287432((S)-2-[(1-{Hydroxy-[(R)-1-(4-nitro-benzoylamino)-2...)
Affinity DataIC50:  50nMAssay Description:In vitro inhibition of phosphoramidon-sensitive membrane bound zinc metalloprotease Endothelin-converting enzyme from partially purified guinea pig l...More data for this Ligand-Target Pair
In DepthDetails Article
TargetNeprilysin(Rattus norvegicus (Rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50287432((S)-2-[(1-{Hydroxy-[(R)-1-(4-nitro-benzoylamino)-2...)
Affinity DataIC50:  55nMAssay Description:Compound was measured for the inhibition of neutral endopeptidase 24.11(NEP).More data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287440((S)-2-[(1-{[(R)-1-((S)-6-Benzyloxycarbonylamino-2-...)
Affinity DataIC50:  60nMAssay Description:In vitro inhibition of phosphoramidon-sensitive membrane bound zinc metalloprotease Endothelin-converting enzyme from partially purified guinea pig l...More data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287430((S)-2-[(1-{[(R)-1-((S)-6-Amino-2-methanesulfonylam...)
Affinity DataIC50:  70nMAssay Description:In vitro inhibition of phosphoramidon-sensitive membrane bound zinc metalloprotease Endothelin-converting enzyme from partially purified guinea pig l...More data for this Ligand-Target Pair
In DepthDetails Article
TargetNeprilysin(Rattus norvegicus (Rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50287430((S)-2-[(1-{[(R)-1-((S)-6-Amino-2-methanesulfonylam...)
Affinity DataIC50:  90nMAssay Description:Compound was measured for the inhibition of neutral endopeptidase 24.11(NEP).More data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287438((S)-2-[(1-{[(R)-1-(4-Aminomethyl-benzoylamino)-2-p...)
Affinity DataIC50:  90nMAssay Description:In vitro inhibition of phosphoramidon-sensitive membrane bound zinc metalloprotease Endothelin-converting enzyme from partially purified guinea pig l...More data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287431((S)-2-({1-[((R)-1-Benzyloxycarbonylamino-2-phenyl-...)
Affinity DataIC50:  120nMAssay Description:In vitro inhibition of phosphoramidon-sensitive membrane bound zinc metalloprotease Endothelin-converting enzyme from partially purified guinea pig l...More data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287437((S)-2-[(1-{Hydroxy-[(R)-1-(4-methoxy-benzoylamino)...)
Affinity DataIC50:  160nMAssay Description:In vitro inhibition of phosphoramidon-sensitive membrane bound zinc metalloprotease Endothelin-converting enzyme from partially purified guinea pig l...More data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287444((S)-2-({1-[((R)-1-Benzyloxycarbonylamino-2-phenyl-...)
Affinity DataIC50:  190nMAssay Description:In vitro inhibition of phosphoramidon-sensitive membrane bound zinc metalloprotease Endothelin-converting enzyme from partially purified guinea pig l...More data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287434((S)-2-({1-[((R)-1-Benzoylamino-2-phenyl-ethyl)-hyd...)
Affinity DataIC50:  250nMAssay Description:In vitro inhibition of phosphoramidon-sensitive membrane bound zinc metalloprotease Endothelin-converting enzyme from partially purified guinea pig l...More data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287445((S)-2-({1-[(Benzyloxycarbonylamino-methyl)-hydroxy...)
Affinity DataIC50:  420nMAssay Description:In vitro inhibition of phosphoramidon-sensitive membrane bound zinc metalloprotease Endothelin-converting enzyme from partially purified guinea pig l...More data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50251742((3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyl-tetrahydro...)
Affinity DataIC50:  500nMAssay Description:In vitro inhibition of phosphoramidon-sensitive membrane bound zinc metalloprotease Endothelin-converting enzyme from partially purified guinea pig l...More data for this Ligand-Target Pair
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287442((S)-2-[(1-{[(R)-1-(2,2-Dimethyl-propionylamino)-2-...)
Affinity DataIC50:  550nMAssay Description:In vitro inhibition of phosphoramidon-sensitive membrane bound zinc metalloprotease Endothelin-converting enzyme from partially purified guinea pig l...More data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287439((S)-2-({1-[((R)-1-Acetylamino-2-phenyl-ethyl)-hydr...)
Affinity DataIC50:  600nMAssay Description:In vitro inhibition of phosphoramidon-sensitive membrane bound zinc metalloprotease Endothelin-converting enzyme from partially purified guinea pig l...More data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287443((S)-2-({1-[((R)-1-Benzyloxycarbonylamino-2-phenyl-...)
Affinity DataIC50: >1.00E+3nMAssay Description:In vitro inhibition of phosphoramidon-sensitive membrane bound zinc metalloprotease Endothelin-converting enzyme from partially purified guinea pig l...More data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50085452((S)-2-[((S)-6-Amino-2-methanesulfonylamino-hexanoy...)
Affinity DataIC50:  1.50E+3nMAssay Description:In vitro inhibition of phosphoramidon-sensitive membrane bound zinc metalloprotease Endothelin-converting enzyme from partially purified guinea pig l...More data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287436((S)-3-(1H-Indol-3-yl)-2-((S)-4-methyl-2-phosphonoa...)
Affinity DataIC50:  1.50E+3nMAssay Description:In vitro inhibition of phosphoramidon-sensitive membrane bound zinc metalloprotease Endothelin-converting enzyme from partially purified guinea pig l...More data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287435((S)-2-[(1-{[(S)-1-((S)-6-Benzyloxycarbonylamino-2-...)
Affinity DataIC50: >1.00E+4nMAssay Description:In vitro inhibition of phosphoramidon-sensitive membrane bound zinc metalloprotease Endothelin-converting enzyme from partially purified guinea pig l...More data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287441((S)-2-({1-[((S)-1-Benzyloxycarbonylamino-2-phenyl-...)
Affinity DataIC50: >1.00E+4nMAssay Description:In vitro inhibition of phosphoramidon-sensitive membrane bound zinc metalloprotease Endothelin-converting enzyme from partially purified guinea pig l...More data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287433((S)-2-[(1-{[(S)-1-((S)-6-Amino-2-methanesulfonylam...)
Affinity DataIC50: >1.00E+4nMAssay Description:In vitro inhibition of phosphoramidon-sensitive membrane bound zinc metalloprotease Endothelin-converting enzyme from partially purified guinea pig l...More data for this Ligand-Target Pair
In DepthDetails Article