Compile Data Set for Download or QSAR
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Found 13 Enz. Inhib. hit(s) with all data for entry = 50004334
TargetDihydrofolate reductase(Mus musculus (Mouse))
TBA

Curated by ChEMBL
LigandPNGBDBM50028533(4-Carbamoyl-2-{4-[(2,4-diamino-pteridin-6-ylmethyl...)
Affinity DataKi:  0.00270nMAssay Description:Inhibition of Dihydrofolate reductase in mouse L1210 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Mus musculus (Mouse))
TBA

Curated by ChEMBL
LigandPNGBDBM50028539(2-{4-[(2,4-Diamino-pteridin-6-ylmethyl)-methyl-ami...)
Affinity DataKi:  0.00270nMAssay Description:Inhibition of Dihydrofolate reductase in mouse L1210 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Mus musculus (Mouse))
TBA

Curated by ChEMBL
LigandPNGBDBM50028542(CHEMBL293546 | derivative of methotrexate)
Affinity DataKi:  0.00280nMAssay Description:Inhibition of Dihydrofolate reductase in mouse L1210 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Mus musculus (Mouse))
TBA

Curated by ChEMBL
LigandPNGBDBM50028536(4-(Carboxymethyl-carbamoyl)-2-{4-[(2,4-diamino-pte...)
Affinity DataKi:  0.00290nMAssay Description:Inhibition of Dihydrofolate reductase in mouse L1210 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Mus musculus (Mouse))
TBA

Curated by ChEMBL
LigandPNGBDBM50028541(2-{4-[(2,4-Diamino-pteridin-6-ylmethyl)-methyl-ami...)
Affinity DataKi:  0.00350nMAssay Description:Inhibition of Dihydrofolate reductase in mouse L1210 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Mus musculus (Mouse))
TBA

Curated by ChEMBL
LigandPNGBDBM50028531(4-Benzylcarbamoyl-2-{4-[(2,4-diamino-pteridin-6-yl...)
Affinity DataKi:  0.00360nMAssay Description:Inhibition of Dihydrofolate reductase in mouse L1210 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Mus musculus (Mouse))
TBA

Curated by ChEMBL
LigandPNGBDBM50028538(CHEMBL293147 | derivative of methotrexate)
Affinity DataKi:  0.00370nMAssay Description:Inhibition of Dihydrofolate reductase in mouse L1210 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Mus musculus (Mouse))
TBA

Curated by ChEMBL
LigandPNGBDBM50028540(2-{4-[(2,4-Diamino-pteridin-6-ylmethyl)-methyl-ami...)
Affinity DataKi:  0.00390nMAssay Description:Inhibition of Dihydrofolate reductase in mouse L1210 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Mus musculus (Mouse))
TBA

Curated by ChEMBL
LigandPNGBDBM18050(2-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)a...)
Affinity DataKi:  0.00430nMAssay Description:Inhibition of Dihydrofolate reductase in mouse L1210 cellsMore data for this Ligand-Target Pair
TargetDihydrofolate reductase(Mus musculus (Mouse))
TBA

Curated by ChEMBL
LigandPNGBDBM50028534(CHEMBL298807 | derivative of methotrexate)
Affinity DataKi:  170nMAssay Description:Inhibition of Dihydrofolate reductase in mouse L1210 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Mus musculus (Mouse))
TBA

Curated by ChEMBL
LigandPNGBDBM50028537(4-(Carboxymethyl-carbamoyl)-4-{4-[(2,4-diamino-pte...)
Affinity DataKi:  208nMAssay Description:Inhibition of Dihydrofolate reductase in mouse L1210 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Mus musculus (Mouse))
TBA

Curated by ChEMBL
LigandPNGBDBM50028535(CHEMBL55797 | derivative of methotrexate)
Affinity DataKi:  208nMAssay Description:Inhibition of Dihydrofolate reductase in mouse L1210 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Mus musculus (Mouse))
TBA

Curated by ChEMBL
LigandPNGBDBM50028532(4-Carbamoyl-4-{4-[(2,4-diamino-pteridin-6-ylmethyl...)
Affinity DataKi:  460nMAssay Description:Inhibition of Dihydrofolate reductase in mouse L1210 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed