Compile Data Set for Download or QSAR
maximum 50k data
Found 90 Enz. Inhib. hit(s) with all data for entry = 587
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Pfizer

LigandPNGBDBM4078(6,7,13,14-tetrahydroxy-2,9-dioxatetracyclo[6.6.2.0...)
Affinity DataIC50:  300nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration, which inhibits 50% of pp60c-src activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Pfizer

LigandPNGBDBM4100(4-[(1,2,6,7-tetrahydroxy-9H-carbazol-9-yl)methyl]b...)
Affinity DataIC50:  400nMAssay Description:IC50 is the inhibitor concentration, which inhibits 50% of pp60c-src activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Pfizer

LigandPNGBDBM4117(3-phenyl-1-(1,2,6,7-tetrahydroxy-9H-carbazol-9-yl)...)
Affinity DataIC50:  400nMAssay Description:IC50 is the inhibitor concentration, which inhibits 50% of pp60c-src activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Pfizer

LigandPNGBDBM4115(9-[(4-methanesulfonylphenyl)carbonyl]-9H-carbazole...)
Affinity DataIC50:  400nMAssay Description:IC50 is the inhibitor concentration, which inhibits 50% of pp60c-src activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Pfizer

LigandPNGBDBM4109(9-(naphthalen-2-ylcarbonyl)-9H-carbazole-1,2,6,7-t...)
Affinity DataIC50:  500nMAssay Description:IC50 is the inhibitor concentration, which inhibits 50% of pp60c-src activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM4099(9-(3-phenylpropyl)-9H-carbazole-1,2,6,7-tetrol | C...)
Affinity DataIC50:  500nMAssay Description:IC50 is the inhibitor concentration, which inhibits 50% of PKA activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] label...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Pfizer

LigandPNGBDBM4099(9-(3-phenylpropyl)-9H-carbazole-1,2,6,7-tetrol | C...)
Affinity DataIC50:  500nMAssay Description:IC50 is the inhibitor concentration, which inhibits 50% of pp60c-src activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Pfizer

LigandPNGBDBM4110(9-[(3-nitrophenyl)carbonyl]-9H-carbazole-1,2,6,7-t...)
Affinity DataIC50:  600nMAssay Description:IC50 is the inhibitor concentration, which inhibits 50% of pp60c-src activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Pfizer

LigandPNGBDBM4108(9-[(4-phenylphenyl)carbonyl]-9H-carbazole-1,2,6,7-...)
Affinity DataIC50:  600nMAssay Description:IC50 is the inhibitor concentration, which inhibits 50% of pp60c-src activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Pfizer

LigandPNGBDBM4106(9-{[4-(benzenesulfonyl)phenyl]methyl}-9H-carbazole...)
Affinity DataIC50:  600nMAssay Description:IC50 is the inhibitor concentration, which inhibits 50% of pp60c-src activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Pfizer

LigandPNGBDBM4093(4-bromo-9H-carbazole-1,2,6,7-tetrol | Carbazole de...)
Affinity DataIC50:  600nMAssay Description:IC50 is the inhibitor concentration, which inhibits 50% of pp60c-src activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM4078(6,7,13,14-tetrahydroxy-2,9-dioxatetracyclo[6.6.2.0...)
Affinity DataIC50:  600nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration, which inhibits 50% of PKA activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] label...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Pfizer

LigandPNGBDBM4111(9-{[4-(trifluoromethyl)phenyl]carbonyl}-9H-carbazo...)
Affinity DataIC50:  700nMAssay Description:IC50 is the inhibitor concentration, which inhibits 50% of pp60c-src activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Pfizer

LigandPNGBDBM4113(9-[(4-tert-butylphenyl)carbonyl]-9H-carbazole-1,2,...)
Affinity DataIC50:  700nMAssay Description:IC50 is the inhibitor concentration, which inhibits 50% of pp60c-src activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Pfizer

LigandPNGBDBM4092(9H-carbazole-1,2,6,7-tetrol | Carbazole deriv. 9b)
Affinity DataIC50:  800nMAssay Description:IC50 is the inhibitor concentration, which inhibits 50% of pp60c-src activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Pfizer

LigandPNGBDBM4101(4-[(4-bromo-1,2,6,7-tetrahydroxy-9H-carbazol-9-yl)...)
Affinity DataIC50:  900nMAssay Description:IC50 is the inhibitor concentration, which inhibits 50% of pp60c-src activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Pfizer

LigandPNGBDBM4103(9-[(2,6-dichlorophenyl)methyl]-9H-carbazole-1,2,6,...)
Affinity DataIC50:  900nMAssay Description:IC50 is the inhibitor concentration, which inhibits 50% of pp60c-src activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Pfizer

LigandPNGBDBM4080(2,3,7,8-tetrahydroxy-5,6-dihydrophenanthridin-6-on...)
Affinity DataIC50:  900nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration, which inhibits 50% of pp60c-src activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Pfizer

LigandPNGBDBM4097(9-benzoyl-9H-carbazole-1,2,6,7-tetrol | Carbazole ...)
Affinity DataIC50:  900nMAssay Description:IC50 is the inhibitor concentration, which inhibits 50% of pp60c-src activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Pfizer

LigandPNGBDBM4085(2,3,8,9-tetrahydroxy-5-[(4-nitrophenyl)methyl]-5,6...)
Affinity DataIC50:  900nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration, which inhibits 50% of pp60c-src activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Pfizer

LigandPNGBDBM4079(2,3,8,9-tetrahydroxy-5,6-dihydrophenanthridin-6-on...)
Affinity DataIC50:  1.00E+3nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration, which inhibits 50% of pp60c-src activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM4109(9-(naphthalen-2-ylcarbonyl)-9H-carbazole-1,2,6,7-t...)
Affinity DataIC50:  1.00E+3nMAssay Description:IC50 is the inhibitor concentration, which inhibits 50% of PKA activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] label...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Pfizer

LigandPNGBDBM4087(5-[(3,4-dichlorophenyl)methyl]-2,3,8,9-tetrahydrox...)
Affinity DataIC50:  1.30E+3nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration, which inhibits 50% of pp60c-src activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Pfizer

LigandPNGBDBM4107(9-[(4-bromophenyl)carbonyl]-9H-carbazole-1,2,6,7-t...)
Affinity DataIC50:  1.40E+3nMAssay Description:IC50 is the inhibitor concentration, which inhibits 50% of pp60c-src activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Pfizer

LigandPNGBDBM4091(9H-carbazole-2,3,6,7-tetrol | Carbazole deriv. 9a)
Affinity DataIC50:  1.50E+3nMAssay Description:IC50 is the inhibitor concentration, which inhibits 50% of pp60c-src activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM4110(9-[(3-nitrophenyl)carbonyl]-9H-carbazole-1,2,6,7-t...)
Affinity DataIC50:  1.50E+3nMAssay Description:IC50 is the inhibitor concentration, which inhibits 50% of PKA activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] label...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Pfizer

LigandPNGBDBM4105(9-[(3-methylphenyl)methyl]-9H-carbazole-1,2,6,7-te...)
Affinity DataIC50:  1.70E+3nMAssay Description:IC50 is the inhibitor concentration, which inhibits 50% of pp60c-src activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Pfizer

LigandPNGBDBM4112(4-bromo-9-{[4-(trifluoromethyl)phenyl]carbonyl}-9H...)
Affinity DataIC50:  2.00E+3nMAssay Description:IC50 is the inhibitor concentration, which inhibits 50% of pp60c-src activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Pfizer

LigandPNGBDBM4089(5-{[4-(benzenesulfonyl)phenyl]methyl}-2,3,8,9-tetr...)
Affinity DataIC50:  2.00E+3nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration, which inhibits 50% of pp60c-src activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Pfizer

LigandPNGBDBM4095(9-benzyl-9H-carbazole-1,2,6,7-tetrol | Carbazole d...)
Affinity DataIC50:  2.00E+3nMAssay Description:IC50 is the inhibitor concentration, which inhibits 50% of pp60c-src activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM4117(3-phenyl-1-(1,2,6,7-tetrahydroxy-9H-carbazol-9-yl)...)
Affinity DataIC50:  2.30E+3nMAssay Description:IC50 is the inhibitor concentration, which inhibits 50% of PKA activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] label...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM4108(9-[(4-phenylphenyl)carbonyl]-9H-carbazole-1,2,6,7-...)
Affinity DataIC50:  3.20E+3nMAssay Description:IC50 is the inhibitor concentration, which inhibits 50% of PKA activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] label...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Pfizer

LigandPNGBDBM4104(9-[(4-bromophenyl)methyl]-9H-carbazole-1,2,6,7-tet...)
Affinity DataIC50:  3.40E+3nMAssay Description:IC50 is the inhibitor concentration, which inhibits 50% of pp60c-src activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Pfizer

LigandPNGBDBM4096(9-benzoyl-9H-carbazole-2,3,6,7-tetrol | Carbazole ...)
Affinity DataIC50:  4.00E+3nMAssay Description:IC50 is the inhibitor concentration, which inhibits 50% of pp60c-src activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM4116(4-bromo-9-[(4-methanesulfonylphenyl)carbonyl]-9H-c...)
Affinity DataIC50:  4.00E+3nMAssay Description:IC50 is the inhibitor concentration, which inhibits 50% of PKA activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] label...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Pfizer

LigandPNGBDBM4081(5-ethyl-2,3,8,9-tetrahydroxy-5,6-dihydrophenanthri...)
Affinity DataIC50:  4.10E+3nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration, which inhibits 50% of pp60c-src activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM4107(9-[(4-bromophenyl)carbonyl]-9H-carbazole-1,2,6,7-t...)
Affinity DataIC50:  4.20E+3nMAssay Description:IC50 is the inhibitor concentration, which inhibits 50% of PKA activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] label...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Pfizer

LigandPNGBDBM4083(5-(Phenylmethyl)-2,3,8,9-tetrahydroxy-6(5H)-phenan...)
Affinity DataIC50:  5.40E+3nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration, which inhibits 50% of pp60c-src activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM4101(4-[(4-bromo-1,2,6,7-tetrahydroxy-9H-carbazol-9-yl)...)
Affinity DataIC50:  6.60E+3nMAssay Description:IC50 is the inhibitor concentration, which inhibits 50% of PKA activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] label...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Pfizer

LigandPNGBDBM4094(9-benzyl-9H-carbazole-2,3,6,7-tetrol | Carbazole d...)
Affinity DataIC50:  7.00E+3nMAssay Description:IC50 is the inhibitor concentration, which inhibits 50% of pp60c-src activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM4112(4-bromo-9-{[4-(trifluoromethyl)phenyl]carbonyl}-9H...)
Affinity DataIC50:  7.00E+3nMAssay Description:IC50 is the inhibitor concentration, which inhibits 50% of PKA activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] label...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Pfizer

LigandPNGBDBM4090(5-{[4-(benzenesulfonyl)phenyl]methyl}-2,3,7,8-tetr...)
Affinity DataIC50:  7.20E+3nMAssay Description:IC50 is the inhibitor concentration, which inhibits 50% of pp60c-src activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Pfizer

LigandPNGBDBM4120(9-[(2,5-dichlorobenzene)sulfonyl]-9H-carbazole-1,2...)
Affinity DataIC50:  7.70E+3nMAssay Description:IC50 is the inhibitor concentration, which inhibits 50% of pp60c-src activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Pfizer

LigandPNGBDBM4098(9-(pyridin-3-ylmethyl)-9H-carbazole-2,3,6,7-tetrol...)
Affinity DataIC50:  8.00E+3nMAssay Description:IC50 is the inhibitor concentration, which inhibits 50% of pp60c-src activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM4085(2,3,8,9-tetrahydroxy-5-[(4-nitrophenyl)methyl]-5,6...)
Affinity DataIC50:  8.40E+3nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration, which inhibits 50% of PKA activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] label...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Pfizer

LigandPNGBDBM4102(9-{[4-(trifluoromethyl)phenyl]methyl}-9H-carbazole...)
Affinity DataIC50:  9.00E+3nMAssay Description:IC50 is the inhibitor concentration, which inhibits 50% of pp60c-src activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Pfizer

LigandPNGBDBM4116(4-bromo-9-[(4-methanesulfonylphenyl)carbonyl]-9H-c...)
Affinity DataIC50:  9.00E+3nMAssay Description:IC50 is the inhibitor concentration, which inhibits 50% of pp60c-src activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM4111(9-{[4-(trifluoromethyl)phenyl]carbonyl}-9H-carbazo...)
Affinity DataIC50:  1.00E+4nMAssay Description:IC50 is the inhibitor concentration, which inhibits 50% of PKA activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] label...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Pfizer

LigandPNGBDBM4082(5-ethyl-2,3,7,8-tetrahydroxy-5,6-dihydrophenanthri...)
Affinity DataIC50:  1.10E+4nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration, which inhibits 50% of pp60c-src activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Pfizer

LigandPNGBDBM4122(9-[(4-nitrobenzene)sulfonyl]-9H-carbazole-1,2,6,7-...)
Affinity DataIC50:  1.20E+4nMAssay Description:IC50 is the inhibitor concentration, which inhibits 50% of pp60c-src activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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