Compile Data Set for Download or QSAR
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Found 25 Enz. Inhib. hit(s) with all data for entry = 50005132
TargetSqualene synthase(Rattus norvegicus)
Glaxo Research And Development

Curated by ChEMBL
LigandPNGBDBM50033185((1S,3R,4S,5R,6R,7R)-1-((4S,5R)-4-Acetyl-5-methyl-3...)
Affinity DataIC50:  4nMAssay Description:In vitro for inhibitory activity against Squalene synthase in ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Glaxo Research And Development

Curated by ChEMBL
LigandPNGBDBM50033196((1S,3S,4S,5R,6R,7R)-1-((4S,5R)-4-Acetyl-5-methyl-3...)
Affinity DataIC50:  7nMAssay Description:In vitro for inhibitory activity against Squalene synthase in ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Glaxo Research And Development

Curated by ChEMBL
LigandPNGBDBM50033184((1S,3S,4S,5R,6R,7R)-1-((4S,5R)-4-Acetyl-5-methyl-3...)
Affinity DataIC50:  10nMAssay Description:In vitro for inhibitory activity against Squalene synthase in ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Glaxo Research And Development

Curated by ChEMBL
LigandPNGBDBM50033199((1S,3S,4S,5R,6R,7R)-1-((4S,5R)-4-Acetyl-5-methyl-3...)
Affinity DataIC50:  12nMAssay Description:In vitro for inhibitory activity against Squalene synthase in ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Glaxo Research And Development

Curated by ChEMBL
LigandPNGBDBM50033187((1S,3R,4S,5R,6R,7R)-1-((4S,5R)-4-Acetyl-5-methyl-3...)
Affinity DataIC50:  25nMAssay Description:In vitro for inhibitory activity against Squalene synthase in ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Glaxo Research And Development

Curated by ChEMBL
LigandPNGBDBM50033181((1S,3S,4S,5R,6R,7R)-1-((4S,5R)-4-Acetyl-5-methyl-3...)
Affinity DataIC50:  26nMAssay Description:In vitro for inhibitory activity against Squalene synthase in ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Glaxo Research And Development

Curated by ChEMBL
LigandPNGBDBM50033192((1S,3R,4S,5R,6R,7R)-1-((4S,5R)-4-Acetyl-5-methyl-3...)
Affinity DataIC50:  43nMAssay Description:In vitro for inhibitory activity against Squalene synthase in ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Glaxo Research And Development

Curated by ChEMBL
LigandPNGBDBM50033205((1S,3R,4S,5R,6R,7R)-1-((4S,5R)-4-Acetyl-5-methyl-3...)
Affinity DataIC50:  57nMAssay Description:In vitro for inhibitory activity against Squalene synthase in ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Glaxo Research And Development

Curated by ChEMBL
LigandPNGBDBM50033186((1S,3R,4S,5R,6R,7R)-1-((4S,5R)-4-Acetyl-5-methyl-3...)
Affinity DataIC50:  63nMAssay Description:In vitro for inhibitory activity against Squalene synthase in ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Glaxo Research And Development

Curated by ChEMBL
LigandPNGBDBM50033200((1S,3S,4S,5R,6R,7R)-1-((4S,5R)-4-Acetyl-5-methyl-3...)
Affinity DataIC50:  72nMAssay Description:In vitro for inhibitory activity against Squalene synthase in ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Glaxo Research And Development

Curated by ChEMBL
LigandPNGBDBM50033190((1S,3R,4S,5R,6R,7R)-1-((4S,5R)-4-Acetyl-5-methyl-3...)
Affinity DataIC50:  92nMAssay Description:In vitro for inhibitory activity against Squalene synthase in ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Glaxo Research And Development

Curated by ChEMBL
LigandPNGBDBM50033183((1S,3R,4S,5R,6R,7R)-1-((4S,5R)-4-Acetyl-5-methyl-3...)
Affinity DataIC50:  146nMAssay Description:In vitro for inhibitory activity against Squalene synthase in ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Glaxo Research And Development

Curated by ChEMBL
LigandPNGBDBM50033193((1S,3S,4S,5R,6R,7R)-1-((4S,5R)-4-Acetyl-5-methyl-3...)
Affinity DataIC50:  147nMAssay Description:In vitro for inhibitory activity against Squalene synthase in ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Glaxo Research And Development

Curated by ChEMBL
LigandPNGBDBM50033195((1S,3R,4S,5R,6R,7R)-1-((4S,5R)-4-Acetyl-5-methyl-3...)
Affinity DataIC50:  156nMAssay Description:In vitro for inhibitory activity against Squalene synthase in ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Glaxo Research And Development

Curated by ChEMBL
LigandPNGBDBM50033182((1S,3R,4S,5R,6R,7R)-1-((4S,5R)-4-Acetyl-5-methyl-3...)
Affinity DataIC50:  172nMAssay Description:In vitro for inhibitory activity against Squalene synthase in ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Glaxo Research And Development

Curated by ChEMBL
LigandPNGBDBM50033197((1S,3S,4S,5R,6R,7R)-1-((4S,5R)-4-Acetyl-5-methyl-3...)
Affinity DataIC50:  220nMAssay Description:In vitro for inhibitory activity against Squalene synthase in ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Glaxo Research And Development

Curated by ChEMBL
LigandPNGBDBM50033194((1S,3S,4S,5R,6R,7R)-1-((4S,5R)-4-Acetyl-5-methyl-3...)
Affinity DataIC50:  310nMAssay Description:In vitro for inhibitory activity against Squalene synthase in ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Glaxo Research And Development

Curated by ChEMBL
LigandPNGBDBM50033198((1S,3R,4S,5R,6R,7R)-1-((4S,5R)-4-Acetyl-5-methyl-3...)
Affinity DataIC50:  312nMAssay Description:In vitro for inhibitory activity against Squalene synthase in ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Glaxo Research And Development

Curated by ChEMBL
LigandPNGBDBM50033204((1S,3R,4S,5R,6R,7R)-1-((4S,5R)-4-Acetyl-5-methyl-3...)
Affinity DataIC50:  357nMAssay Description:In vitro for inhibitory activity against Squalene synthase in ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Glaxo Research And Development

Curated by ChEMBL
LigandPNGBDBM50033191((1S,3R,4S,5R,6R,7R)-1-((4S,5R)-4-Acetyl-5-methyl-3...)
Affinity DataIC50:  442nMAssay Description:In vitro for inhibitory activity against Squalene synthase in ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Glaxo Research And Development

Curated by ChEMBL
LigandPNGBDBM50033203((1S,3R,4S,5R,6R,7R)-1-((4S,5R)-4-Acetyl-5-methyl-3...)
Affinity DataIC50:  505nMAssay Description:In vitro for inhibitory activity against Squalene synthase in ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Glaxo Research And Development

Curated by ChEMBL
LigandPNGBDBM50033202((1S,3R,4S,5R,6R,7R)-1-((4S,5R)-4-Acetyl-5-methyl-3...)
Affinity DataIC50:  785nMAssay Description:In vitro for inhibitory activity against Squalene synthase in ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Glaxo Research And Development

Curated by ChEMBL
LigandPNGBDBM50033188((1S,3R,4S,5R,6R,7R)-1-((4S,5R)-4-Acetyl-5-methyl-3...)
Affinity DataIC50:  1.18E+3nMAssay Description:In vitro for inhibitory activity against Squalene synthase in ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Glaxo Research And Development

Curated by ChEMBL
LigandPNGBDBM50033201((1S,3R,4S,5R,6R,7R)-1-((4S,5R)-4-Acetyl-5-methyl-3...)
Affinity DataIC50:  1.94E+3nMAssay Description:In vitro for inhibitory activity against Squalene synthase in ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Glaxo Research And Development

Curated by ChEMBL
LigandPNGBDBM50033189((1S,3R,4S,5R,6R,7R)-1-((4S,5R)-4-Acetyl-5-methyl-3...)
Affinity DataIC50:  2.88E+3nMAssay Description:In vitro for inhibitory activity against Squalene synthase in ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed