Compile Data Set for Download or QSAR
maximum 50k data
Found 20 Enz. Inhib. hit(s) with all data for entry = 50036301
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
University Of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM82517(2-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-...)
Affinity DataKi:  0.600nMAssay Description:In vitro binding affinity to 5-hydroxytryptamine 1A receptor using [125I](R)-(+)-trans-8-OH-PIPAT as radioligand in rat hippocampal homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
University Of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50035512(CHEMBL140697 | N-{2-[4-(2-Methoxy-phenyl)-piperazi...)
Affinity DataKi:  2.20nMAssay Description:In vitro binding affinity to 5-hydroxytryptamine 1A receptor in rat hippocampal homogenate by [125I](R)-(+)-trans-8-OH-PIPAT displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
University Of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50035515(CHEMBL410521 | N-{2-[4-(2-Methoxy-phenyl)-piperazi...)
Affinity DataKi:  2.5nMAssay Description:In vitro binding affinity to 5-hydroxytryptamine 1A receptor in rat hippocampal homogenate by [125I](R)-(+)-trans-8-OH-PIPAT displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
University Of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50035508(4-Iodo-N-{2-[4-(2-methoxy-phenyl)-piperazin-1-yl]-...)
Affinity DataKi:  2.60nMAssay Description:In vitro binding affinity to 5-hydroxytryptamine 1A receptor in rat hippocampal homogenate by [125I](R)-(+)-trans-8-OH-PIPAT displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
University Of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50035513(4-Fluoro-N-{2-[4-(2-methoxy-phenyl)-piperazin-1-yl...)
Affinity DataKi:  3.20nMAssay Description:In vitro binding affinity to 5-hydroxytryptamine 1A receptor in rat hippocampal homogenate by [125I](R)-(+)-trans-8-OH-PIPAT displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
University Of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50035510(4-Chloromethyl-N-{2-[4-(2-methoxy-phenyl)-piperazi...)
Affinity DataKi:  3.5nMAssay Description:In vitro binding affinity to 5-hydroxytryptamine 1A receptor in rat hippocampal homogenate by [125I](R)-(+)-trans-8-OH-PIPAT displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
University Of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50035518(4-Ethyl-N-{2-[4-(2-methoxy-phenyl)-piperazin-1-yl]...)
Affinity DataKi:  9.30nMAssay Description:In vitro binding affinity to 5-hydroxytryptamine 1A receptor in rat hippocampal homogenate by [125I](R)-(+)-trans-8-OH-PIPAT displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
University Of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50035514(CHEMBL142082 | N-{2-[4-(2-Methoxy-phenyl)-piperazi...)
Affinity DataKi:  10nMAssay Description:In vitro binding affinity to 5-hydroxytryptamine 1A receptor in rat hippocampal homogenate by [125I](R)-(+)-trans-8-OH-PIPAT displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
University Of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50035525(4-Amino-N-{2-[4-(2-methoxy-phenyl)-piperazin-1-yl]...)
Affinity DataKi:  10nMAssay Description:In vitro binding affinity to 5-hydroxytryptamine 1A receptor in rat hippocampal homogenate by [125I](R)-(+)-trans-8-OH-PIPAT displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
University Of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50035524(4-Butyl-N-{2-[4-(2-methoxy-phenyl)-piperazin-1-yl]...)
Affinity DataKi:  13nMAssay Description:In vitro binding affinity to 5-hydroxytryptamine 1A receptor in rat hippocampal homogenate by [125I](R)-(+)-trans-8-OH-PIPAT displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
University Of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50035511(CHEMBL139869 | N-{2-[4-(2-Methoxy-phenyl)-piperazi...)
Affinity DataKi:  16nMAssay Description:In vitro binding affinity to 5-hydroxytryptamine 1A receptor in rat hippocampal homogenate by [125I](R)-(+)-trans-8-OH-PIPAT displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
University Of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50035516(4-Amino-3-iodo-N-{2-[4-(2-methoxy-phenyl)-piperazi...)
Affinity DataKi:  18nMAssay Description:In vitro binding affinity to 5-hydroxytryptamine 1A receptor in rat hippocampal homogenate by [125I](R)-(+)-trans-8-OH-PIPAT displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
University Of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50035521(4-(2-Chloro-acetylamino)-N-{2-[4-(2-methoxy-phenyl...)
Affinity DataKi:  22nMAssay Description:In vitro binding affinity to 5-hydroxytryptamine 1A receptor in rat hippocampal homogenate by [125I](R)-(+)-trans-8-OH-PIPAT displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
University Of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50035517(4-Azido-3-iodo-N-{2-[4-(2-methoxy-phenyl)-piperazi...)
Affinity DataKi:  25nMAssay Description:In vitro binding affinity to 5-hydroxytryptamine 1A receptor in rat hippocampal homogenate by [125I](R)-(+)-trans-8-OH-PIPAT displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
University Of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50035519(4-tert-Butyl-N-{2-[4-(2-methoxy-phenyl)-piperazin-...)
Affinity DataKi:  27nMAssay Description:In vitro binding affinity to 5-hydroxytryptamine 1A receptor in rat hippocampal homogenate by [125I](R)-(+)-trans-8-OH-PIPAT displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
University Of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50035523(4-Hexyl-N-{2-[4-(2-methoxy-phenyl)-piperazin-1-yl]...)
Affinity DataKi:  58nMAssay Description:In vitro binding affinity to 5-hydroxytryptamine 1A receptor in rat hippocampal homogenate by [125I](R)-(+)-trans-8-OH-PIPAT displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
University Of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50035520(CHEMBL141071 | N-{2-[4-(2-Methoxy-phenyl)-piperazi...)
Affinity DataKi:  75nMAssay Description:In vitro binding affinity to 5-hydroxytryptamine 1A receptor in rat hippocampal homogenate by [125I](R)-(+)-trans-8-OH-PIPAT displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
University Of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50035509(4-Heptyl-N-{2-[4-(2-methoxy-phenyl)-piperazin-1-yl...)
Affinity DataKi:  82nMAssay Description:In vitro binding affinity to 5-hydroxytryptamine 1A receptor in rat hippocampal homogenate by [125I](R)-(+)-trans-8-OH-PIPAT displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
University Of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM86708(CAS_146714-97-8 | CHEMBL31354 | CHEMBL514874 | CHE...)
Affinity DataIC50:  2.20nMAssay Description:In vitro binding affinity to 5-hydroxytryptamine 1A receptor using [125I](R)-(+)-trans-8-OH-PIPAT as radioligand in rat hippocampal homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
University Of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50047471((S)-N-tert-butyl-3-(4-(2-methoxyphenyl)piperazin-1...)
Affinity DataIC50:  15nMAssay Description:In vitro binding affinity to 5-hydroxytryptamine 1A receptor using [125I](R)-(+)-trans-8-OH-PIPAT as radioligand in rat hippocampal homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed