Compile Data Set for Download or QSAR
maximum 50k data
Found 13 Enz. Inhib. hit(s) with all data for entry = 50036244
TargetNociceptin receptor(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM21864((21R)-22-(cyclopropylmethyl)-14-oxa-11,22-diazahep...)
Affinity DataKi:  0.0300nMAssay Description:Binding affinity against delta-opioid receptor in guinea pig brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50038641(22-cyclopropylmethyl-(2R,13S)-14-oxa-4,22-diazahep...)
Affinity DataKi:  2.20nMAssay Description:Binding affinity against delta-opioid receptor in guinea pig brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM21864((21R)-22-(cyclopropylmethyl)-14-oxa-11,22-diazahep...)
Affinity DataKi:  3.80nMAssay Description:Binding affinity against mu-opioid receptor in guinea pig brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50038641(22-cyclopropylmethyl-(2R,13S)-14-oxa-4,22-diazahep...)
Affinity DataKi:  4.90nMAssay Description:Binding affinity against mu-opioid receptor in guinea pig brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50038641(22-cyclopropylmethyl-(2R,13S)-14-oxa-4,22-diazahep...)
Affinity DataKi:  33nMAssay Description:Binding affinity against kappa-opioid receptor in guinea pig brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM21864((21R)-22-(cyclopropylmethyl)-14-oxa-11,22-diazahep...)
Affinity DataKi:  332nMAssay Description:Binding affinity against kappa-opioid receptor in guinea pig brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50038642(22-methyl-(2R,13S)-14-oxa-4,22-diazaheptacyclo[13....)
Affinity DataIC50:  920nMAssay Description:Antagonist activity against mu-opioid receptor in guinea pig ileum in the presence of morphineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50038642(22-methyl-(2R,13S)-14-oxa-4,22-diazaheptacyclo[13....)
Affinity DataIC50:  990nMAssay Description:Antagonist activity against kappa-opioid receptor in guinea pig ileum in the presence of ethylketazocineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(MOUSE)
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50038642(22-methyl-(2R,13S)-14-oxa-4,22-diazaheptacyclo[13....)
Affinity DataIC50:  1.00E+3nMAssay Description:Antagonist activity against delta-opioid receptor in mouse vas deferens in the presence of DADLEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM21864((21R)-22-(cyclopropylmethyl)-14-oxa-11,22-diazahep...)
Affinity DataIC50:  2.00E+3nMAssay Description:Antagonist activity against kappa-opioid receptor in guinea pig ileum in the presence of ethylketazocineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(MOUSE)
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50038641(22-cyclopropylmethyl-(2R,13S)-14-oxa-4,22-diazahep...)
Affinity DataIC50:  8.20E+3nMAssay Description:Antagonist activity against delta-opioid receptor in mouse vas deferens in the presence of DADLEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM21864((21R)-22-(cyclopropylmethyl)-14-oxa-11,22-diazahep...)
Affinity DataIC50:  1.12E+4nMAssay Description:Antagonist activity against mu-opioid receptor in guinea pig ileum in the presence of morphineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(MOUSE)
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM21864((21R)-22-(cyclopropylmethyl)-14-oxa-11,22-diazahep...)
Affinity DataIC50:  4.59E+5nMAssay Description:Antagonist activity against delta-opioid receptor in mouse vas deferens in the presence of DADLEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed