Compile Data Set for Download or QSAR
maximum 50k data
Found 30 Enz. Inhib. hit(s) with all data for entry = 50006026
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Università

Curated by ChEMBL
LigandPNGBDBM50008735((+)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,...)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of binding of radioligand [3H]-spiroperidol to dopamine D2 receptor in rat striatal membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Università

Curated by ChEMBL
LigandPNGBDBM21393(7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-1-o...)
Affinity DataIC50:  1.10nMAssay Description:In vitro ability of the compound to inhibit binding of radioligand [3H]-8-OH-DPAT to 5-hydroxytryptamine 1A receptor in rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Università

Curated by ChEMBL
LigandPNGBDBM50043891(1-[3-(8-Methoxy-3,4-dihydro-naphthalen-1-yl)-propy...)
Affinity DataIC50:  1.40nMAssay Description:In vitro ability of the compound to inhibit binding of radioligand [3H]-8-OH-DPAT to 5-hydroxytryptamine 1A receptor in rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Università

Curated by ChEMBL
LigandPNGBDBM50043882(1-[3-(6-Methoxy-3,4-dihydro-naphthalen-1-yl)-propy...)
Affinity DataIC50:  2nMAssay Description:In vitro ability of the compound to inhibit binding of radioligand [3H]-8-OH-DPAT to 5-hydroxytryptamine 1A receptor in rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Università

Curated by ChEMBL
LigandPNGBDBM50043892(1-[3-(8-Methoxy-3,4-dihydro-naphthalen-1-yl)-propy...)
Affinity DataIC50:  8.80nMAssay Description:In vitro ability of the compound to inhibit binding of radioligand [3H]-8-OH-DPAT to 5-hydroxytryptamine 1A receptor in rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Università

Curated by ChEMBL
LigandPNGBDBM50001859((buspirone) 8-[4-(4-Pyrimidin-2-yl-piperazin-1-yl)...)
Affinity DataIC50:  12.8nMAssay Description:In vitro ability of the compound to inhibit binding of radioligand [3H]-8-OH-DPAT to 5-hydroxytryptamine 1A receptor in rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Università

Curated by ChEMBL
LigandPNGBDBM50043884(1-[3-(3,4-Dihydro-naphthalen-1-yl)-propyl]-4-(2-me...)
Affinity DataIC50:  14.7nMAssay Description:Inhibition of binding of radioligand [3H]-spiroperidol to dopamine D2 receptor in rat striatal membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Università

Curated by ChEMBL
LigandPNGBDBM50043884(1-[3-(3,4-Dihydro-naphthalen-1-yl)-propyl]-4-(2-me...)
Affinity DataIC50:  15.7nMAssay Description:In vitro ability of the compound to inhibit binding of radioligand [3H]-8-OH-DPAT to 5-hydroxytryptamine 1A receptor in rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Università

Curated by ChEMBL
LigandPNGBDBM50043892(1-[3-(8-Methoxy-3,4-dihydro-naphthalen-1-yl)-propy...)
Affinity DataIC50:  17.4nMAssay Description:Inhibition of binding of radioligand [3H]-spiroperidol to dopamine D2 receptor in rat striatal membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Università

Curated by ChEMBL
LigandPNGBDBM50043893(1-[3-(8-Methoxy-3,4-dihydro-naphthalen-1-yl)-propy...)
Affinity DataIC50:  18.3nMAssay Description:In vitro ability of the compound to inhibit binding of radioligand [3H]-8-OH-DPAT to 5-hydroxytryptamine 1A receptor in rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Università

Curated by ChEMBL
LigandPNGBDBM50043886(1-(3-Chloro-phenyl)-4-[3-(8-methoxy-3,4-dihydro-na...)
Affinity DataIC50:  31.4nMAssay Description:In vitro ability of the compound to inhibit binding of radioligand [3H]-8-OH-DPAT to 5-hydroxytryptamine 1A receptor in rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Università

Curated by ChEMBL
LigandPNGBDBM50043888(1-[3-(8-Methoxy-3,4-dihydro-naphthalen-1-yl)-propy...)
Affinity DataIC50:  55.9nMAssay Description:In vitro ability of the compound to inhibit binding of radioligand [3H]-8-OH-DPAT to 5-hydroxytryptamine 1A receptor in rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Università

Curated by ChEMBL
LigandPNGBDBM50043881(1-[3-(6-Methoxy-3,4-dihydro-naphthalen-1-yl)-propy...)
Affinity DataIC50:  63.6nMAssay Description:In vitro ability of the compound to inhibit binding of radioligand [3H]-8-OH-DPAT to 5-hydroxytryptamine 1A receptor in rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Università

Curated by ChEMBL
LigandPNGBDBM50043882(1-[3-(6-Methoxy-3,4-dihydro-naphthalen-1-yl)-propy...)
Affinity DataIC50:  90.6nMAssay Description:Inhibition of binding of radioligand [3H]-spiroperidol to dopamine D2 receptor in rat striatal membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Università

Curated by ChEMBL
LigandPNGBDBM50043891(1-[3-(8-Methoxy-3,4-dihydro-naphthalen-1-yl)-propy...)
Affinity DataIC50:  119nMAssay Description:Inhibition of binding of radioligand [3H]-spiroperidol to dopamine D2 receptor in rat striatal membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Università

Curated by ChEMBL
LigandPNGBDBM50043885(1-(3-Chloro-phenyl)-4-[3-(6-methoxy-3,4-dihydro-na...)
Affinity DataIC50:  131nMAssay Description:In vitro ability of the compound to inhibit binding of radioligand [3H]-8-OH-DPAT to 5-hydroxytryptamine 1A receptor in rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Università

Curated by ChEMBL
LigandPNGBDBM50043889(1-[3-(6-Methoxy-3,4-dihydro-naphthalen-1-yl)-propy...)
Affinity DataIC50:  138nMAssay Description:In vitro ability of the compound to inhibit binding of radioligand [3H]-8-OH-DPAT to 5-hydroxytryptamine 1A receptor in rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Università

Curated by ChEMBL
LigandPNGBDBM50043887(1-[3-(6-Methoxy-3,4-dihydro-naphthalen-1-yl)-propy...)
Affinity DataIC50:  147nMAssay Description:In vitro ability of the compound to inhibit binding of radioligand [3H]-8-OH-DPAT to 5-hydroxytryptamine 1A receptor in rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Università

Curated by ChEMBL
LigandPNGBDBM50043883(1-(2,5-Dimethoxy-phenyl)-4-[3-(6-methoxy-3,4-dihyd...)
Affinity DataIC50:  161nMAssay Description:In vitro ability of the compound to inhibit binding of radioligand [3H]-8-OH-DPAT to 5-hydroxytryptamine 1A receptor in rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Università

Curated by ChEMBL
LigandPNGBDBM50043883(1-(2,5-Dimethoxy-phenyl)-4-[3-(6-methoxy-3,4-dihyd...)
Affinity DataIC50:  201nMAssay Description:Inhibition of binding of radioligand [3H]-spiroperidol to dopamine D2 receptor in rat striatal membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Università

Curated by ChEMBL
LigandPNGBDBM50001859((buspirone) 8-[4-(4-Pyrimidin-2-yl-piperazin-1-yl)...)
Affinity DataIC50:  222nMAssay Description:Inhibition of binding of radioligand [3H]-spiroperidol to dopamine D2 receptor in rat striatal membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Università

Curated by ChEMBL
LigandPNGBDBM50043893(1-[3-(8-Methoxy-3,4-dihydro-naphthalen-1-yl)-propy...)
Affinity DataIC50:  303nMAssay Description:Inhibition of binding of radioligand [3H]-spiroperidol to dopamine D2 receptor in rat striatal membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Università

Curated by ChEMBL
LigandPNGBDBM50043886(1-(3-Chloro-phenyl)-4-[3-(8-methoxy-3,4-dihydro-na...)
Affinity DataIC50:  484nMAssay Description:Inhibition of binding of radioligand [3H]-spiroperidol to dopamine D2 receptor in rat striatal membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Università

Curated by ChEMBL
LigandPNGBDBM50043888(1-[3-(8-Methoxy-3,4-dihydro-naphthalen-1-yl)-propy...)
Affinity DataIC50:  644nMAssay Description:Inhibition of binding of radioligand [3H]-spiroperidol to dopamine D2 receptor in rat striatal membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Università

Curated by ChEMBL
LigandPNGBDBM50043885(1-(3-Chloro-phenyl)-4-[3-(6-methoxy-3,4-dihydro-na...)
Affinity DataIC50:  768nMAssay Description:Inhibition of binding of radioligand [3H]-spiroperidol to dopamine D2 receptor in rat striatal membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Università

Curated by ChEMBL
LigandPNGBDBM50043887(1-[3-(6-Methoxy-3,4-dihydro-naphthalen-1-yl)-propy...)
Affinity DataIC50:  777nMAssay Description:Inhibition of binding of radioligand [3H]-spiroperidol to dopamine D2 receptor in rat striatal membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Università

Curated by ChEMBL
LigandPNGBDBM50043881(1-[3-(6-Methoxy-3,4-dihydro-naphthalen-1-yl)-propy...)
Affinity DataIC50:  778nMAssay Description:Inhibition of binding of radioligand [3H]-spiroperidol to dopamine D2 receptor in rat striatal membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Università

Curated by ChEMBL
LigandPNGBDBM50043889(1-[3-(6-Methoxy-3,4-dihydro-naphthalen-1-yl)-propy...)
Affinity DataIC50:  1.29E+3nMAssay Description:Inhibition of binding of radioligand [3H]-spiroperidol to dopamine D2 receptor in rat striatal membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Università

Curated by ChEMBL
LigandPNGBDBM50043890(1-[3-(6-Methoxy-3,4-dihydro-naphthalen-1-yl)-propy...)
Affinity DataIC50: >1.00E+4nMAssay Description:In vitro ability of the compound to inhibit binding of radioligand [3H]-8-OH-DPAT to 5-hydroxytryptamine 1A receptor in rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Università

Curated by ChEMBL
LigandPNGBDBM50043890(1-[3-(6-Methoxy-3,4-dihydro-naphthalen-1-yl)-propy...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of binding of radioligand [3H]-spiroperidol to dopamine D2 receptor in rat striatal membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed